Department of Laboratory Medicine
Niigata University School of Medicine

Publications in English(1976-Present) 

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2015

  1. Sugru Yamamoto, Junichiro J. Kazama, Kentaro Omori, Koji Matsuo, Yoshimitsu Takahashi, Kazuko Kawamura, Takayuki Matsuto, Hiroshi Watanabe, Toru Maruyama, Ichiei Narita: Continuous Reduction of Protein-Bound Uraemic Toxins with Improved Oxidative Stress by Using the Oral Charcoal Adsorbent AST-120 in Haemodialysis Patients. SCIENTIFIC REPORTS (5): 2015.

2014

  1. Ami Aoki, Hiroshi Moro, Tkayuki Watanabe, Katsuki Asakawa, Satoru Miura, Masato Moriyama, Yoshinari Tanabe, Hiroshi Kagami, Ichiei Narita: A case of severe thrombocytopaenia associated with acute HIV-1 infection. Int J STD AIDS 26(3): 209-11, 2014.doi: 10.1177/0956462414531937. Epub 2014.
  2. Yuka Koike, Tomohiko Ishihara, Tetsutaro Ozawa, Naomi Mezaki, Hiroshi Moro, Takayoshi Shimohata Masatoyo Nishizawa: Cryptococcal meningitis successfully treated with voriconazole and low-dose amphotericin B. Neurology Clinical Neuroscience 5(2):166-168, 2014.
  3. Kenjiro Shima, Takuro Sakagami, Yoshinari Tanabe, Nobumasa Aoki, Hiroshi Moro, Toshiyuki Koya, Hiroshi Kagamu, Tkashi Hasegawa, Ei-ichi Suzuki, Ichiei Narita: Novel assay to detect increased level of neutralizing anti-interferon gamma autoantibodies in non-tuberculous mycobacterial patients. J Infect Chemother 20(1):52-6, 2014.doi: 10.1016/j.jiac.2013.08.003. Epub 2013 Dec 11.

2012

  1. Toshinari Aoki, Tsueko Abe, Eiji Yamada, Takayuki Matsuto, Masahiko Okada: Increased LDL susceptibility to oxidation accelerates future carotid artery atherosclerosis. Lipids in Health and Disease, 11: 1-7, 2012.

2011.

  1. Richiro Ishida, Masahiko Okada: Association of Trait Anxiety and Social Desirability with White Blood Cell counts. The Open Psychiatry Journal 5: 1-4, 2011.
  2. Riichiro Ishida, Masahiko Okada: Factors influencing the development of “Purpose in Life” and its relationship to coping with mental stress. Psycology 2(1): 29-34, 2011.
  3. Riichiro Ishida, Tsueko Abe, Masahiko Okada: Firmness of purpose in life significantly influences emotional state and automatic nervous activity. Health 3(8): 507-511, 2011.
  4. Tsueko Abe, Toshinari Aoki Syogo Yata, Masahiko Okada: Sleep duration is significantly associated with carotid artery atherosclerosis incidence in a Japanese population. Atherosclerosis 217: 509-513, 2011.
  5. Michael A. Grandner, Shawn D. Youngstedt: Sleep duration and cardiometabolic risk Commentary on Abe et al., “Sleep duration is significantly associated with carotid artery atherosclerosis incidence in a Japanese population” Atherosclerosis 217: 324-325, 2011.
  6. Hirokazu Kawai, Minoru Nomoto, Takeshi Suda, Kenya Kamimura Atsunori Tsuchiya, Yasushi Tamura, Masahiko Yano, Masaki Takamura, Masato Igarashi, Toshifumi Wakai, Satoshi Yamagiwa, Yasunobu Matsuda, Shogo Ohkoshi, Isao Kurosaki, Yoshio Shirai, Masahiko Okada, Yutaka Aoyagi: Multicentric occurrence of hepatocellular carcinoma with nonalcoholic steatohepatitis. World J Gastroenterol 3(1): 15-23, 2011.

2010.

  1. Riichiro Ishida, Masahiko Okada: Association of trait anxiety and social deirability with white blood cell counts. Open Psych J 4: 27-30, 2010.
  2. Tsueko Abe, Akiko Tsuda, Syogo Yata, Tkayuki Matsuto, Masahiko Okada: Hypertension is a major risk factor for future atherosclerotic changes in the lapanese population. Ann Clin Biochem 47: 118-124, 2010.
  3. Yasushi Tamura, Masato Igarashi, Hirokazu Kawai, Takeshi Suda, shinnji Satomura, Yutaka Aoyagi: Clinical Advantage of Highly Sensitive On-Chip Immunoassay for Fucosylated Fraction of Alpha-Fetoprotein in Patients with Hepatocellular Carcinoma. Dig Dis sci Published online: 21 April 2010
  4. Akira Osaki, Tomoyuki Kubota, Takeshi Suda, Masato Igarashi, Keisuke Nagasaki, Atsunori Tsuchiya, Masahiko Yano, Yasushi Tamura, Masaki Takamura, Hirokazu Kawai, Satoshi Yamagiwa, Toru Kikuchi, Minoru Nomoto, Yutaka Aoyagi: Shear wave velocity is a useful marker for managing nonalcoholic steatohepatitis. World J Gastroenterol 16(23): 2918-25, 2010.
  5. Chiba N, Morozumi M, Sunaoshi K, Takahashi S, Takano M, Komori T, Sunakawa K, Ubukata K; IPD Surveillance Study Group. Serotype and antibiotic resistance of isolates from patients with invasive pneumococcal disease in Japan. Epidemiol Infect. 2010 Jan;138(1):61-8.

2009

  1. Masayoshi Masuko, Tatsuo Furukawa, Takashi Abe, Reiko Wada, Soichi Maruyama, Toshiki Kitajima Yasuhiko Shibasaki Ken Toba, Masahiko Okada, Yoshifusa Aizawa: A chronic myeloid leukemia patient with atypical karyotype and BCR-ABL e13a3 transcript caused by complex chromosome rearrangement. Int J Hematol 90: 230-234, 2009.
  2. Takuya Watanabe, Kenji Soga, Haruka Hirono, Katsuhiko Hasegawa, Koichi Shibasaki, Hirokazu Kawai, Yutaka Aoyagi: Features of hepatocellular carcinoma in cases with autoimmune hepatitis and primary biliary cirrhosis.: World J Gastroenterol 15(2):231-239, 2009.
  3. Takeshi Suda, Kenya Kamimura, Tomoyuki Kubota, Yasushi Tamura, Masato Igarashi, Hirokazu Kawai, Yutaka Aoyagi, Dexi Liu: Progress toward liver-based gene therapy. Hepatol Res. 39(4):325-340, 2009.

2008

  1. Elfi Wardaningsih, Takashi Miida, Utako Seino, Yuriko Fueki, Masayuki Ito, Keisuke Nagasaki, Toru Kikuchi, Makoto Uchiyama, Satoshi Hirayama, Osamu Hanyu, Kazunori Miyake, Masahiko Okada: Low adiponectin state is associated with metabolic abnormalities in obese children, particularly depending on apolipoprotein E phenotype. Ann Clin Biochem 45(5): 496-503, 2008.
  2. Shin-ichi Toyabe, Takayuki Matsuto, Tatsuo Ushiki and Kohei Akazawa: Image database and image analysis of chromosome information. Chromosome Nanoscience and Technology, CRC Press, FL, USA, pp.245-257, 2008..
  3. Takashi Miida, Utako Seino, Osamu Miyazaki, Osamu Hanyu, Satoshi Hirayama, Toshikazu Saito, Yuichi Ishikawa, Suguru Akamatsu, Toshimitu Nakano, Katsuyuki Nakajima, Mitsuyo Okazaki, Masahiko Okada: Probucol markedly reduces HDL phospholipids and elevated preβ1-HDL without delayed conversion into α-migrating HDL: Putative role of angiopoietin-like protein 3 in probucol-induced HDL remodeling. Atherosclerosis 200(2): 329-335, 2008.
  4. Hironori Nagasaka, Takashi Miida Kenichi Hirano, Akemi Ota, Tohru Yorifuji, Tomozumi Takatani, Hirokazu Tsukahara, Masaki Takayanagi, Shu-Ping Hui, Kunihiko Kobayashi, and Hitoshi Chiba: Reduced apolipoprotein E-rich high-density lipoprotein level at birth is restored to the normal range in patients with familial hypercholesterolemia in the first year of life. J Clin Endocrinol Metab 93(3): 779-783, 2008.
  5. Riichiro Ishida: Correlations between purpose in life(ikigai) and state anxiety in schizoid temperament with considerations of early life, youth, and adulthood experiences. Acta Med Biol 56(1): 27-32, 2008
  6. Ritsuko Satoh, Hiroki Tsukada, Yoshinari Tanabe, Yukiko Tamura, Tatsuo Yamamoto, Misao Takano, Kyoko Ozaki, Takashi Tamura, Fumitake Gejyo: An autbreak and isolation of drug-resistant Pseudomonas aeruginosa at Niigata University Hospital, Japan. J infect Chmother 14(8): 325-329, 2008.

2007

  1. Takashi Miida, Akihiro Takahashi, Takeshi Ikeuchi: Prevention of stroke and dementia by statin therapy: Experimental and clinical evidence of their pleiotropic effects, Pharmacology & amp. Therapeutics 113(2): 378-393, 2007.
  2. Hironori Nagasaka, Ken-ichi Hirano, Akira Ohtake, Takashi Miida, Tomozumi Takatani, Kei Murayama, Tohru Yorifuji, Kunihiko Kobayashi, Masaki Kanazawa, Atsushi Ogawa, Masaki Takayanagi: Improvements of hypertriglyceridemia and hyperlacticemia in Japanese children with glycogen storage disease type Ia by medium-chain triglyceride milk. European Journal of Pediatrics 166(10): 1009-1016, 2007.
  3. Hironori Nagasaka, Hitoshi Chiba, Shu-Ping Hui, Hazime Takikawa, Takashi Miida, Masaki Takayanagi, Tohru Yorifuji, Makoto Hasegawa, Akemi Ota, Ken-ichi Hirano, Hideaki Kikuchi, Hirokazu Tsukahara, Kunihiko Kobayashi: Depletion of high-density lipoprotein and appearance of triglyceride-rich low-density lipoprotein in a Japanese patient with FIC1 deficiency manifesting benign recurrent intrahepatic cholestasis. Journal of Pediatric Gastroenterology and Nutrition 45(1): 96-105, 2007.
  4. Satoshi Hirayama, Takashi Miida, Osamu Miyazaki, Yoshifusa Aizawa: Preβ1-HDL concentration is a predictor of carotid atherosclerosis in type 2 diabetic patients. Diabetes Care 30(5): 1289-1291, 2007.
  5. Yuriko Fueki, Takashi Miida, Elfi Wardaningsih, Masayuki Ito, Akira Nakamura, Akihiro Takahashi, Osamu Hanyu,Akiko Tsuda, Hisashi Saito, Hitoshi Hama, Masahiko Okada: Regular alcohol consumption improvesinsulin resistance in healthy Japanese men independent of obesity. Clin Chim Acta 382(1-2): 71-76, 2007.
  6. Hiroe Sato, Takashi Miida, Yoko Wada, Mitsuya Mruyama, Shuichi Murakami, Hisashi Hasegawa, Takeshi Kuroda, Ichiei Narita, Fumitake Gejyo: Atherosclerosis is accelerated in well-controlled Systemic Lupus Erythematosus (SLE) even in the premenopausal state, and further exaggerated in the postmenopausal state. Clin Chim Acta. 385(1-2): 35-42, 2007.
  7. Hiroyuki Ebinuma, Takashi Miida, Toshimasa Yamauchi, Yusuke Hada, Kazuo Hara, Naoto Kubota, Takashi Kadowaki: Improved ELISA assay for selective measurements of adiponectin multimers, and identification of adiponectin in human cerebrospinal fluid. Clin Chem 53(8): 1541-1544, 2007.
  8. Osamu Hanyu, Takashi Miida, Keiichiro Kosuge, Takako Ito, Satoshi Soda, Satoshi Hirayama, Elfi Wardaningsih, Yuriko Fueki, Konen Obayashi, Yoshifusa Aizawa: Preheparin lipoprotein lipase mass is a practical marker of insulin resistance in ambulatory type 2 diabetic patients treated with oral hypoglycemic agents. Clin Chim Acta 384(1-2): 118-123, 2007

2006

  1. Richiro Ishida, Masahiko Okada: Effects of a firm purpose in life on anxiety and sympathetic nervous activity caused by emotional stress: assessment by psycho-physiological method. Stress and Health 22: 275-281, 2006.
  2. P. Cao, S. Toyabe, S. Kurashima, M. Okada, K. Akazawa: A modified method of activity-based costing for objectively reducing cost drivers in hospitals. Methods Inf Med 45: 462-469, 2006.
  3. Takashi Miida. The rationale for statin therapy in Alzheimer’s dementia:what we know and what we do not. commentary on the topics of atherosclerosis, International Atherosclerosis Society(http://www.athero.org/comm-index.asp), 2006.
  4. Takashi Miida, Toshiyuki Yamada, Utako Seino, Masayuki Ito, Yuriko Fueki,Akihiro Takahashi, Keiichiro Kosuge, Satoshi Soda, Osamu Hanyu, Konen Obayashi, Osamu Miyazaki, Masahiko Okada: Serum amyloid A (SAA)-induced remodeling of CSF-HDL. Biochim Biophys Acta 1761(4): 424-433, 2006.
  5. Keiichiro Kosuge, Tkashi Miida, Akihiro Takahashi, Konen Obayashi, Masayuki Ito, Takako Ito, Satoshi Soda, KazuyukiOzaki, Satoshi Hirayama, Osamu Hanyu, Yoshifusa Aizawa, Yuichi Nakamura: Estimating the fasting triglyceride concentration from the postprandial HDL cholesterol and apolipoprotein CIII concentrations. Atherosclerosis 184(2): 413-419, 2006.
  6. Kozo Ninomiya, Akihiro Takahashi, Yoshio Fujioka, Yuichi Ishikawa, Mitsuhiro Yokoyama: Transforming growth factor-beta signaling enhances transdifferentiation of macrophages into smooth muscle-like cells. Hypertens Res 29:269-276, 2006.
  7. Hiroshi Okamoto, Yoshio Fujioka, Akihiro Takahashi, Tomosaburo Takahashi, Takahiro Taniguchi, Yuichi Ishikawa, Mitsuhiro Yokoyama: Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). J Atheroscler Thromb 13:183-191, 2006.
  8. Kohei Kamemura, Yoshio Fujioka, Hiroshi Takaishi, Akihiro Takahashi, Takahiro Taniguchi, Yuichi Ishikawa, Mitsuhiro Yokoyama: Chylomicron remnants upregulate CD40 expression via the ERK pathway and a redox-sensitive mechanism in THP-1 cells. Atherosclerosis 187: 257-264, 2006.
  9. Ying Zhu, Jian Yao, Yiman Meng, Ayumi Kasai, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Takashi Miida, Masayuki Takeda, Masahiko Okada, Masanori Kitamura. Profiling of functional phosphodiesterase in mesangial cells using a CRE-SEAP-based reporting system. Br J Pharmacol 148(6): 833-844, 2006.

2005

  1. Masahiko Okada, Tomohiro Saito, Hajime Yoshimura, Yasuhiko Noguchi, Taeko Ito, Hiroko Sasaki, Hitoshi Hama: Surfactant-based homogeneous assay for the Measurement of triglyceride concentrations in VLDL and intermediate-density lipoprotein. Clin Chem 51(10): 1804-1810, 2005.
  2. Ying Zhu, Masahiko Okada, Takayuki Matsuto, Takashi Miida: Prediction of the three-dimensional structure of proteins in the Lipid monolayer on the basis of α-helix bunding the apolipoprotein B-100 structure. Acta Med Biol 53(2): 51-60, 2005.
  3. Takashi Miida, Akihiro Takahashi, Naohito Tanabe, Takeshi Ikeuchi. Can statins really reduce the risk of Alzheimer’s disease and slow its progression? Curr Opin Lipidol 16(6): 619-623, 2005.
  4. Daisuke Saga, Minoru Sakatsume, Asa Ogawa, Yutaka Tsubata, Yoshikatsu Kaneko, Takeshi Kuroda, Fuminori Sato, Junya Ajiro, Daisuke Kondo, Takashi Miida, Ichiei Narita, Fumitake Gejyo: Bezafibrate suppresses rat anti-glomerular basement membrane crescentic glomerulonephritis. Kidney International 67(5): 1821-1829, 2005.
  5. Satoshi Hirayama, Takashi Miida, Konen Obayashi, Fusako Yamazaki, Miho Yamazaki-Sakurai, Masayuki Ito, Yuji Saito, Osamu Hanyu, Katsunori Suzuki, Yoshifusa Aizawa: Effect of apolipoprotein E (apoE) phonotypes on apoE content of CSF-HDL in children. Clin Chim Acta 356(1-2): 110-116, 2005.
  6. Yuuko Takahashi, Yoshio Fujioka, Tomosaburo Takahashi, Kojo Domoto, Akihiro Takahashi, Takahiro Taniguchi, Yuichi Ishikawa, Mitsuhiro Yokoyama: Chylomicron remnants regulate early growth response factor-1 in vascular smooth muscle cells. Life Sci 77: 670-682, 2005
  7. Konen Obayashi, Osamu Hanyu, Takashi Miida, Yukio Ando, Masaaki Nakamura, Ying Zhu, and Masahiko Okada: Circadian rhythm of protein Clin human plasma: Useful marker of autonomic function in liver. Clin Auton Res 15: 57-58, 2005.
  8. Taro Yamashita, Yukio Ando, Shoichi Katsuragi, Masaaki Nakamura, Konen Obayashi, Katsuki Haraoka, Mitsuharu Ueda, Sun Xuguo, Sadahisa Okamoto, and Makoto Uchino: Muscular Amyloid Angiopathy with Amyloidgenic Transthyretin Ser50Ile and Tyr114Cys. Muscle Nerve 31: 41-45, 2005.

2004

  1. Masahiko Okada, Takayuki Matsuto, Takashi Miida, Konen Obayashi, Ying Zhu, and Yuriko Fueki: Lipid analyses for the management of vascular diseases. J Atheroscler Thromb 11(4): 190-199, 2004.
  2. Osamu Sugita, Nobuhito Ishizawa, Takayuki Matsuto, Masahiko Okada, Norihiko Kayahara: A new method of measuring the antioxidant  activity of polyphenols using cumene hydroperoxide. Ann Clin Biochem 41: 72-77, 2004. 
  3. Takashi Miida, Bo Zhang, Konen Obayashi, Utako Seino, Ying Zhu, Takako Ito, Yuichi Nakamura, Masahiko Okada, Keijiro Saku: T13M mutation of lecithin-cholesterol acyltransferase gene causes fish-eye disease. Clin Chim Acta 343(1-2): 201-208, 2004.
  4. Takashi Miida, Konen Obayashi, Utako Seino, Ying Zhu, Takako Ito, Keiichiro Kosuge, Satoshi Hirayama, Osamu Hanyu, Yuichi Nakamura, Toshio Yamaguchi, Takashi Tsuda, Yuji Saito, Osamu Miyazaki, Yasushi Nakamura, Masahiko Okada: LCAT-dependent conversion rate is a determinant of plasma preß1-HDL concentration in healthy Japanese. Clin Chim Acta 350: 107-114, 2004.
  5. Takashi Miida, Satoshi Hirayama, Yuichi Nakamura: Cholesterol-independent effects of statins and its new therapeutic targets: ischemic stroke and dementia. J Atheroscler Thromb 11( 5): 253-264, 2004.
  6. Osamu Hanyu, Takashi Miida, Konen Obayashi, Tomoo Ikarashi T, Satoshi Soda, Susumu Kaneko, Satoshi Hirayama, Katsunori Suzuki, Yuichi Nakamura , Keiichi Yamatani, Yoshifusa Aizawa: Lipoprotein Lipase (LPL) mass in pre-heparin serum reflects insulin sensitivity. Atherosclerosis 174(2): 385-390, 2004.
  7. Konen Obayashi, Yukio Ando, Masaaki Nakamura, Taro Yamashita, Mitsuharu Ueda, Katsuki Haraoka, Hisayasu Terazaki, Makoto Uchino: Near-infrared spectrophotoscopy in assessment of autonomic dysfunction. Neurology 63: 164-166, 2004.
  8. Konen Obayashi, Yukio Ando, Takashi Miida, Masaaki Nakamura, Taro Yamashita, Mitsuharu Ueda, Katsuki Haraoka, Hisayasu Terazaki, Masahiko Okada: Macroscopic assesment of skin venules in patients with familial amyloidotic polyneuropathy (FAP) using near-infrared spectrophotoscopy as a markerof autonomic dysfunction. Amyloid and Amyloidosis. (Gilles G editor), CRC Press 334-336, 2004.
  9. Taro Yamashita, Yukio Ando, Masaaki Nakamura, Konen Obayashi, HisayasuTerazaki, Katsuki Haraoka, Xuguo Sun, Mitsuharu Ueda, Makoto Uchino: Inhibitory effect of α-tocopherol on methylmercury-induced oxidativestress. Environ Health Prev Med 9: 111-117, 2004.

2003

  1. .Pengyu Cao, Masao Hashiba, Kouhei Akazawa, Tomoko Yamakawa, Takayuki Matsuto.: An integrated medical image database and retrieval system using a web application server. Int J Med Inform, 71: 51-55, 2003.
  2. Takashi Miida, Osamu Miyazaki, Osamu Hanyu, Yuichi Nakamura, Satoshi Hirayama, Ichiei Narita, Fumitake Gejyo, Isei Ei, Kazuyuki Tasaki, Yutaka Kohda, Takashi Ohta, Syogo Yata, Isamu Fukamachi Masahiko Okada: LCAT-Dependent Conversion of Preβ1-HDL into α-Migrating HDL is Severely Delayed in Hemodialysis Patients.J Am Soc Nephrol 14: 732-738, 2003.
  3. Takashi Miida, Osamu Miyazaki, Yasushi Nakamura, Satoshi Hirayama, Osamu Hanyu, Isamu Fukamachi, Masahiko Okada: Analytical performance of a sandwich enzyme immunoassay for preβ1-HDL in stabilized plasma. Journal of Lipid Research 44: 645-650, 2003.
  4. Seitaro Maruyama, Kiminori Kato, Makoto Kodama, Yuji Okura, Satoru Hirono, Koichi Fuse, Haruo Hanawa, Osamu Nakagawa, Mikio Nakazawa, Takashi Miida, Eisin Yaoita, Tadashi Yamamoto, Ikuo Inoue, Yoshifusa Aizawa. FR167653 suppresses the progression of experimental autoimmune myocarditis. Mol Cell Biochem 246(1-2): 39-44, 2003. 
  5. Taku Matsubara, Takaharu Ishibashi, Tomoyuki Hori, Kazuyuki Ozaki, Tohru Mezaki, Keiichi Tsuchida, Akimitsu Nasuno, Kaname Kubota, Takayuki Tanaka, Takashi Miida, Yoshifusa Aizawa, Matomo Nishio: Association between coronary endothelial dysfunction and local inflammation of atherosclerotic coronary arteries. Mol Cell Biochem 249(1-2): 67-73, 2003.
  6. Tohru Mezaki, Taku Matsubara, Tomoyuki Hori, Kohtarou Higuchi, Akira Nakamura, Iwao Nakagawa, Shunsuke Imai, Kazuyuki Ozaki, Keiichi Tuchida, Akimitsu Nasuno, Takayuki Tanaka, Kaname Kubota, Masahiko Nakano, Takashi Miida, Yoshifusa Aizawa: Plasma levels of soluble thrombomodulin, C-reactive protein and serum amyloid A protein in the atherosclerotic coronary circulation. Jpn Heart J 44(5): 601-612, 2003.

 

2002

  1. Tomoo Ando, Akira Tanaka, Sadahumi Fukasaku, Ristuko Takada, Masahiko Okada, Kazuhiko Ukai, Kazuhiko Shizuka, Hiroshi Oyamada, Haruo Toda, Tomokazu Taniyama, Tomoaki Usui Makoto Yoshizawa, Tooru Kiryu, Mineo Takagi, Shinya Saida, Takehiko Bando: Pupillary and cardiovascular responses to a video movie in senior human subjects. Auton Neurosc 97: 129-135, 2002.
  2. Takashi Miida, Yuichi. Nakamura, Toru Mezaki, Osamu Hanyu, Seitaro Maruyama, Yoshinori Horikawa, Sachiko Izawa, Yukio Yamada, Hiroshi Matsui and Masahiko Okada: LDL-cholesterol and HDL-cholesterol decrease during the day. Ann Clin Biochem 39:241-249, 2002.
  3. Seitaro Maruyama, Kiminori Kato, Makoto Kodama, Satoru Hirono, Koichi Fuse, Osamu Nakagawa, Mikio Nakazawa, Takashi Miida, Kenichi Watanabe, Tadashi Yamamoto, Yoshifusa Aizawa: Fenofibrate, a peroxisome proliferator-activated receptor α activator, suppresses experimental autoimmune myocarditis by stimulating the interleukin-10 pathway in rats. J Atheroscler Thromb 9(2): 87-92, 2002.
  4. Takahiro Murai, Toshiyuki Ymada, TakashiMida,Katsumitsu Arai, Naoto Endo Tadamasa Hanyu: Fenofibrate inhibits reactive amyloidosis in mice. Arthritis & Rheumatism 46(6): 1683-1688, 2002.

 

2001

  1. Masahiko Okada, Hiroshi Matsui, Yasuki Ito, Akira Fujiwara: Direct measurement of HDL cholesterol: Method Eliminating apolipoprotein E-rich Particles. J Clin Lab Ana 15: 223-229, 2001.
  2. Masahiko Okada, Riichiro Ishida: Direct Measurement of Low-Density-Lipoprotein Cholesterol Is More Effective Than Total Cholesterol for the Purpose of Lipoprotein Screening. Prev Med 32: 224-229, 2001.
  3. Riichiro Ishida, Masahiko Okada: Endurance training in young subjects: Effects on the autonomic nervous system. Acta Medica et Biologica 49(2): 53-60, 2001.
  4. Motohiko Kimura, Yoshihiko Tomita, Tomoyuki Imai, Toshihiro Saito, Akiyoshi Katagiri, Yukie O-hara-Mikami, Takayuki Matsuto, Kota Takahashi: Significance of serum amyloid A on the prognosis in patients with renal cell carcinoma. Cancer 92(8): 2072-2075, 2001.
  5. Minoru Sakatsume, Moritoshi Kadomura, Iku Sakata, Naofumi Imai, Daisuke Kondo, Yutaka Osawa, Hisaki Shimada, Mitsuhiro Ueno, Takashi Miida, Shinichi Nishi, Masaki Akazawa, Fumitake Gejyo: Novel glomerular lipoprotein deposits associated with apolipoprotein E2 homozygosity. Kidney International 59(5): 1911-1918, 2001.
  6. Kouiti Taira, Hideki Bujo, Satoshi Hirayama, Hiroyuki Yamazaki, Tatsuro Kanaki, Kazuo Takahashi, I. Ishii, Takashi Miida, Wolfgang Johann Schneider, Yasushi Saito: LR11, A Mosaic LDL receptor family member, mediates the uptake of apo E-rich lipoproteins in vitro. Arterioscler Thromb Vasc Biol 21(9): 1501-1506, 2001.
  7. Kuniko Okumura-Noji, Kanna Sasai, Renli Zhan, Hitoshi Kawaguchi, Haruhiko Maruyama, Toyohiro Tada, Hikaru Takahashi, Mitsuyo Okazaki, Takashi Miida, N. Sakuma, Genjiro Kimura, Nobuo Ohta, Shinji Yokoyama: Cholesteryl ester transfer protein-deficiency causes slow egg embryonation of Shistosoma japonicum. Biochem Biophys Res Commun 286(2): 305-310, 2001.
  8. H. Takahashi, T. Furukawa, S. Hashimoto, N. Suzuki, T. Kuroha, F. Yamazaki, K. Inano, M. Takahashi, Y. Aizawa, T. Koike: Contribution of TNF-alpha and IL-10 gene polymorphisms to graft-versus-host disease following allo-hematopoietic stem cell transplantation. Bone Marrow Transplant 26: 1317-1323, 2001.
  9. Tatsuo Furukawa, Shigeo Hashimoto, Koichi Inano, Fusako Yamazaki, Hiroko Takeda, Toshio Kakihara, Toshio Yano, Takashi Abe, Wataru Higuchi, Ken Toba, Masuhiro Takahashi, Tadashi Koike, Yoshifusa Aizawa: Analysis of chimerism in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation. Rinsho Ketsueki 42: 488-495, 2001.
  10. Osamu. Miyazaki, Junji. Kobayashi, Isamu. Fukamachi, Takashi. Miida, Hideki. Bujo, Yasushi. Saito: A new sandwich enzyme immunoassay for measurement of plasma pre-β1-HDL levels. J Lipid Res 41(12): 2083-2088, 2001.

2000

  1. Masahiko Okada, Takashi Miida, Hitoshi Hama, Shogo Yata, Takao Sunaga, Akiko Tsuda, Hisashi Saito: Possible risk factors of carotid artery atherosclerosis in the Japanese population: A primary prevention study in non-diabetic subjects. Int Med 39(5): 362-368, 2000.
  2. Masahiko Okada, Takashi Miida, Akira Fujiwara, Noriyoshi Inomata: Autoantibodies against oxidized low-density lipoprotein correlate with Achilles tendon xanthoma. Clin Chem Lab Med 38(6): 501-506, 2000.
  3. Takumi Kurabayashi, Masahiko Okada, Kenichi Tanaka: Eicosapentaenoic acid effect on hyperlipidemia in menopausal Japanese women. Obst Gyne 96(4): 521-528, 2000.
  4. Masao Hashida, Takayuki Matsuto, Futoshi Arai, Tomoko Yamakawa, Kouhei Akazawa: Accessing endoscopic images for remote conference and diagnosis using WWW server with a secure socket layer. Journal of Medical Systems 24(6): 333-338, 2000.
  5. Masao Hashiba, K. Inagawa, Takayuki Matsuto, A. Motonaga, Tomoko Yamakawa, Kouhei Akazawa: Application of the RealAudio package to computerized medical lectures. Med Inform 25(4): 239-245, 2000.
  6. Takashi Miida, Kazuyuki Ozaki, Toru Murakami, Takayuki Kashiwa, Toru Yamadera, Takashi Tsuda, Koichi Inano, Masahiko Okada: Preβ1- high-density lipoprotein (preβ1-HDL) concentration can change with low-density lipoprotein-cholesterol (LDL-C) concentration independent of cholesteryl ester transfer protein (CETP). Clin Chim Acta 292: 69-80, 2000.
  7. Takashi Miida, Katsuyuki Sakai, Kazuyuki Ozaki, Yuichi Nakamura, Toshio Yamaguchi, Takashi Tsuda, Takayuki Kashiwa, Toru Murakami, Koichi Inano, Masahiko Okada: Bezafibrate increases pre β1-HDL at the expense of HDL2 in hypertriglyceriemia. Arterioscler. Thromb Vasc Biol 20(11): 2428-2433, 2000. 
  8. Osamu Miyazaki, Junji Kobayashi, Isamu Fukamachi, Takashi Miida, Hideaki Bujo, Yasushi Saito: A new sandwich enzyme immunoassay for measurement of plasma pre-1-HDL levels. J Lipid Res 41(12): 2083-2088, 2000.
  9. Kouchi Inano, Isao Suetake, Takayuki Ueda, Yasuko Miyake, Masahiko Nakamura, Masahiko Okada, Shoji Tajima: Maintenance-type DNA methyltransferase is highly expressed in post-mitotic neurons and localized in the cytoplasmic compartment. J Biochem 128(2): 315-321, 2000.
  10. Kouchi Inano, Shizuo Tezuka, Takashi Miida, Masahiko Okada: Capillary isotachophoretic analysis of serum lipoproteins using a carrier ampholyte as spacer ion. Ann Clin Biochem 37: 708-716, 2000.
  11. Masahiro Ito, Hidenobu Takahashi, Koichi Fuse, Satoru Hirono, Takashi Washizuka, Kiminori Kato, Fusako Yamazaki, Koichi Inano, Tatsuo Fukukawa, Makoto Komada, Yoshifusa Aizawa: Polymorohisms of tumor necrosis factor-α and interleukin-10genes  in Japanese patients with idiopathic dilated cardiomyopathy. Jap Heart J 41(2): 183-191, 2000.

1999

  1. Masahiko Okada: Conference report: 12th Fall Conference of the Japanese Society of Medical Electronics and Biological Engineering(JSMBE). IFMBE News 36: 6-7, 1999.
  2. Takashi Miida, Fusako Yamazaki, Miho Sakurai, Reiko Wada, Tohru Yamadera, Katsuhisa Asami, Mari Hoshiyama, Atsushi Tanaka, Koichi Inano, Masahiko Okada: The apolipoprotein E content of HDL in cerebrospinal fluid is higher in children than in adults. Clin Chem 45(8): 1294-1296, 1999.
  3. Takashi Miida, Toshiyuki Yamada, Toru Yamadera, Kazuyuki Ozaki, Koichi Inano, Masahiko Okada: Serum amyloid A protein generates pre ß1 high-density lipoprotein from α-migrating high-density lipoprotein. Biochemistry 38(51): 16958-16962, 1999.

1998

  1. Masahiko Okada, Hiroshi Matsui, Yasuki Itoh, Akira Fujiwara, Koichi Inano: Low-density lipoprotein cholesterol can be chemically measured: a new superior method. J Lab Clin Med 132(3): 195-201, 1998.
  2. Masahiko Okada, Marino Hoshiyama: Authors' reply to Letter to the Editor, Oxidation of LDL cholesterol. Ann Clin Biochem 34: 1-2, 1998.
  3. Riichiro Ishida, Masahiko Okada: Effects of physical training on heart rate variability and blood cell counts in healthy adults. Acta Med Biol 46: 139-146, 1998.
  4. Mihoko Okada, Minoru Takaba, Shigekoto Kaihara, Masahiko Okada: Formal representation of summary tables for health care statistical database management. Comput Biomed Res 31: 426-450, 1998.
  5. Takashi Miida, Hideaki Otsuka, Atsushi Tsuchiya, Masahiko Okada: Plasma lipoprotein profiles change significantly during cardiac catheterization. Clin Chem 44(3): 517-521, 1998.
  6. Takashi Miida, Toshio Yamaguchi, Takashi Tsuda, Masahiko Okada: High preβ1-HDL levels in hypercholesterolemia are maintained by probucol but reduced by a low-cholesterol diet. Atherosclerosis 138: 129-134, 1998.
  7. Takashi Ohyama, Hiromi Tsujibayashi, Hideki Tagashira, Koichi Inano, Takayuki Ueda, Yoshiko Hirota, Koichiro Hashimoto: Suppression of electrophoretic anomaly of bent DNA segments by the structural property that causes rapid migration. Nuc Acids Res 26(21): 4811-4817, 1998.

1997

  1. Masahiko Okada, Takayuki Matsuto, Takashi Miida, Koichi Inano: Differences in the effects of cytokines on the expression of adhesion molecules in endothelial cells. Ann Med Int 148(2): 125-129, 1997.
  2. Masahiko Okada, Yasuki Itoh, Koichi Inano, Takashi Miida, Takayuki Matsuto: Structural changes in oxidative modification of low density lipoprotein: investigation by lipid peroxidation products, surface charge, and spetcrophotometric patterns. Ann Clin Biochem 34: 173-178, 1997.
  3. Takashi Miida, Koichi Inano, Toshio Yamaguchi, Takashi Tsuda, Masahiko Okada: Lpa-l levels do not reflect preβ1-HDL levels in human plasma. Atherosclerosis 133: 221-226, 1997.
  4. Toshiyuki Yamada, Takashi Miida: Serum amyloid A remains physiological concentrations in coronary atherosclerosis. Clin.Chem. 43(1): 193, 1997.
  5. T. Asami, K. Inano, T. Miida, T. Kikuchi, M. Uchiyama: Two families of low occulocerebrorenal syndrome with elevated serum HDL levels and CETP gene mutation. Acta Ped 86: 41-46, 1997.
  6. Toshiyuki Yamada, Takashi Miida, Tetsuji Yamaguchi, Yoshihisa Itoh: Effect of serum amyloid A on cellular affinity of low density lipoprotein. Eur J Clin Chem Clin Biochem 35(6): 421-426, 1997.

1996

  1. Masahiko Okada, Takayuki Matsuto, Shuuichi Satoh, Shuuichi Igarashi, Miyako Baba, Osamu Sugita, Mihoko Okada: Role of pulse wave velocity for assessing autonomic nervous system activities in reference to heart rate variability. Med Inf 21(1): 81-90, 1996.
  2. Masahiko Okada: Internet revolutions: present and future of laboratory data communication within and between hospitals, Proceedings of the 7th Asian-Pacific Congress of Clinical Biochemistry: 61-63, 1996.
  3. Masahiko Okada, Osamu Sugita, Takayuki Matsuto, Takashi Miida, Koichi Inano: Endothelial cell damage: the effects of mechanical forces produced by flow division. Cell Eng. 1(4): 183-187, 1996.
  4. Minoru Fukuda, Tetsuya Moroda, Shinichi Toyabe, Tsuneo Iiai, Yasuyuki Kawachi, Hiromi Takahashi-Iwanaga, Toshihiko Iwanaga, Masahiko Okada, Toru Abo: Granulocytosis induced by increasing sympathetic nerve activity contributes to the incidence of acute appendicitis. Biomed Res 17(2): 171-181, 1996.
  5. Takashi Miida, Yuichi Nakamura, Masahiko Okada: Development of coronary atherosclerosis in asymptomatic heterozygous patients with familial hypercholestrolemia. J Cardiol 28(2): 71-77, 1996.
  6. Takashi Miida, Yuichi Nakamura, Koichi Inano, Takayuki Matsuto, Toshio Yamaguchi, Takashi Tsuda, Masahiko Okada: Pre β1-high-density lipoprotein increases in coronary artery disease. Clin Chem 42(12): 1992-1995, 1996.
  7. Toshiyuki Yamada, Takashi Miida, Yoshihisa Itoh, Tadashi Kawai, Merrill D Benson: Characterization of serum amyloid A4 as a plasma apolipoprotein. Clin Chim Acta 251: 105-112, 1996.

1995

  1. Masahiko Okada, Osamu Sugita, Takashi Miida, Takayuki Matsuto, Koichi Inano: Effects of modified low density lipoprotein and hypoxia on the expression of endothelial leukocyte adhesion molecule-1. Eur J Med (La Presse Medicale), 24(10): 483-488, 1995.
  2. Satoshi Kimura, Osamu Sugita, Takayuki Matsuto, Masahiko Okada, Yasuyuki Igarashi: HPLC application for phosphoinositides analyses of A431 cells and human platelets. Acta Med Biol 43(1): 59-62, 1995.
  3. Osamu Sugita, Yae Tomiyama, Takayuki Matsuto, Masahiko Okada, Fumitake Gejo, Masaaki Arakawa, S.Takahashi, Y.Watazu, N.Kaneda: A new enzymatic method for the determination of inulin. Ann Clin Biochem 32: 561 -565, 1995.
  4. Takayuki Nemoto, Tomonori Matsuzaka, Minoru Ota, Yuko Ohara-Nemoto, Masaru Kaneko, Tsuneyoshi Horigome Koichi Inano: Kinship between self -oligomerizing and the estrogen receptor interacting activities of the 90- kDa heat shock protein. Steroid Biochem (Life Sci. Ady. ): 59-67, 1995.

1994

  1. Masahiko Okada, Takayuki Matsuto, Osamu Sugita, Satoshi Kimura, Hideaki Matsumoto, Tokuhiro Okada: A simple method to measure red blood cell deformability by centrifugation. Eur J Med (La Presse Medicale) 23(5): 1613-1615, 1994.
  2. Masahiko Okada, Osamu Sugita, Takashi Miida, Yuko Makino, Noriko Komoro: Endothelial cell responses to controlled pulsatile flow at the bifurcation of a model vessel. 16th Annual International Conference of the IEEE/EMBS 1: 291-292, 1994.
  3. Toshiyuki Yadada, Toshihiko Kakihara, Fumitake Gejyo, Masahiko Okada: A monoclonal antibody recognizing apolipoprotein E peptides in systemic amyloid deposits. Ann Clin Lab 24(3), 1994.
  4. Kouichi Inano, Sylvia W. Curtis, Kenneth S. Korach, Saburo Omata, Tsuneyoshi Horigome: Heat shock protein 90 strongly stimulates the binding of purified estrogen receptor to its responsive element. J Biochem 116(4): 759-766, 1994.
  5. Toshiyuki Yamada, Barbara Kluve-Beckerman, William M. kuster, Juris J. Liepnieks Merrill D. Benson: Measurement of serum amyloid A4(SAA4): its constitutive presence in serum. Int J Exp Clin Invest 1: 114-118, 1994.
  6. Toshiyuki Yamada, Barbara Kluve-Beckerman, Juris J. Liepnieks Merrill D. Benson: Fibril formation from recombinant human serum amyloid A. Amiloid Biochimica et Biophysica Acta 1266: 323-329, 1994.

1993

  1. Masahiko Okada, Osamu Sugita, Yuko Makino, Takayuki Matsuto, Lan Hongxing: A system for generating pulsatile flow and shear stress to investigate cultured vascular cell functions. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 15, IEEE Press: New York, pp. 922-923, 1993.
  2. Mihoko Okada, Myles O'Brien, Masahiko Okada: IntroStat: a Hypertext-based electronic textbook to introduce fundamental methods of biomedical statistics. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society  15, IEEE Press: New York, pp. 634-635, 1993.
  3. Toshiyuki Yamada, Yasuhiro Nomata, Osamu Sugita, Masahiko Okada: A rapid method for measuring serum amyloid A protein by latex agglutination nephelometric immunoassay. Ann Clin Biochem 30: 72-76, 1993.
  4. Toshiyuki Yamada, Osamu Sugita, Masahiko Okada, Takayuki Matsuto: Use of chemiluminescent acridinium ester label for cellular uptake assay of low density lipoprotein. Ann Clin Biochem 30: 490-491, 1993.
  5. Tetsuo Nakayama, Satomi Sonoda, Takashi Urano, Toshiyuki Yamada, Masahiko Okada: Monitoring both serum amyloid protein A and C-reactive protein as inflammatory markers in infection diseases. Clin Chem 39(2): 293-297, 1993.
  6. Hiroyuki Miwata, Toshiyuki Yamada, Masahiko Okada, Toyoichiro Kudo, Hiroshi Kimura, Tsuneo Morishima: Serum amyloid A protein in acute viral infections. Arch. Dis. Child. 68: 210-214, 1993.
  7. Mikihiko Kawano, Takashi Miida, Christopher J. Fielding, Phoebe E. Fielding: Quantitation of prebeta-HDL dependent and nonspecific components of the total efflux of cellular cholesterol and phospholipid. Biochemistry 32: 5025- 5028, 1993.

1992

  1. Mihoko Okada, Masahiko Okada, Hideo Tohma, Akinori, Hisashige, Tetsuo Kawamura, Koji Yamamoto: A study on appropriate allocation of comedical staff in hospital. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 1150-1151, 1992.
  2. Osamu Sugita, Toshiyuki Yamada, Masahiko Okada, Kunio Takeuchi: Reference values of serum and urine creatinine, and of creatinine clearnace by a new enzymatic method. Ann Clin Biochem 29: 523-528, 1992.
  3. Osamu Sugita, Toshiyuki Yamada, Takayuki Matsuto, Masahiko Okada: Preparation of LDL from dextran-sulfate cellulose column after plasmapheresis. Progress in Clinical Biochemistry, Excerpta Medica: Tokyo, pp. 467-468, 1992.
  4. Takashi. Miida, M. Kawano, C.J. Fielding, P.E. Fielding: Regulation of the concentration of prebeta high-density lipoprotein in normal plasma by cell membranes and lecithin-cholesterol acyltranferase activity. Biochemistry 31(45): 11112-11117, 1992.
  5. Koichi Inano, Takehiko Ishida, Saburo Omata, Tsuneyoshi Horigome: In Vitro formation of estrogen receptor-heat shock protein 90 complexes. J Biochem 112(4): 535- 540, 1992.
  6. Satoshi Kimura, Shigeyuki Kawa, Fugiang Ruan, Mohammad Nisar, Yoshito Sadahira, Sen-Itiroh Hakomori, Yasuyuki Igarashi: Effect of sphingosine and its N-methyl derivatives on oxidative burst, phagokinenetic activity, and trans-endothelial migration of human neutrophils. Biochemical Pharmacology 44(8): 1858-1595, 1992.

1991

  1. Masahiko Okada: A method to evaluate arterial pulse wave velocity by age and blood pressure. J. Clin. Comput. 20(1): 1-20, 1991.
  2. Masahiko Okada,  Mihoko Okada: The pursuit of a portable clinical data base system written by FORTRAN, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 1212-1213, 1991.
  3. Masahiko Okada: Usefulness of daily patients data for monitoring laboratory test results, Quality Control in the Clinical Laboraotry '91, Excerpta Medica: Tokyo, pp. 289-300, 1991.
  4. Phoebe E. Fielding, Takashi Miida, Christopher J. Fielding: Metabolism of low-density lipoprotein free cholesterol by human plasma lecithin-cholesterol acyltransferase. Biochemistry 30(35): 8551-8557, 1991.
  5. Masahide Yamamoto, Yoshiaki Takahashi, Koichi Inano, Tsuneyoshi Horigome, Hiroshi Sugano: Characterization of the hydrophobic region of heat shock protein 90. J. Biochem. 110(1): 141-145, 1991.
  6. Tomomi Kuwana, Osamu Sugita, Minoru Yakata: Sugar chain heterogeneity of bone and liver alkaline phosphatase in serum. Enzyme 45: 63-66, 1991.
  7. Hirofumi Okoshi, Sen-itiroh Hakomori, Mohammad Nisar, Qinghong Zhou, Satoshi Kimura, et al: Cell membrane signaling as target in cancer therpy II: inhibitory effect of N, N, N-trimethylsphingosine on metastatic potential of murine B16 melanoma cell line through blocking of tumor cell-dependent platelet aggregation. Cancer Research 51(15): 6019-6024, 1991.
  8. S. Kimura, D. Saitou, A. Singhal, S. Hakomori: Diagnostic and prognostic significance for early stage lung cancer by cytological sputum examination with anti-carbohydrate monoclonal anti-bodies. Glycoconjugate J. 8(3): 178, 1991.

1990

  1. Masahiko Okada: Arterial pulse wave velocity as a meausre of cardiovascular stress, proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 550-551, 1990.
  2. Masahiko Okada: Method for quality control of laboratory tests using histograms of daily patient data. J. Clin. Comput. 18(5), (6): 120-129, 1990.
  3. Kazuo Hikosaka, Takayuki Matsuto, et al: Three regions in the anterior bank of the caudal superior temporal sulcus of the macaque monkey. Vision, Memory, and the Temporal Lobe: 347-353, 1990.
  4. Takayuki Matsuto, et al: Laboratory test scheduling based on constraint propagation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society 12(3), 1990.
  5. Kouichi Inano, Makoto Haino, Masaomi Iwasaki, Naomi Ono, Tsuneyoshi Horigome, Hiroshi Sugano: Reconstitution of the 9S estrogen receptor with heat shokck protein 90. FEBS Letters 267(1): 157-159, 1990.
  6. Tomomi Kuwana, and Sidney B. Rosalki: Intestinal variant alkaline phosphatase in plasma in disease. Clin Chem 36(11): 1918-1921, 1990.

1989

  1. Masahiko Okada, Mihoko Okada: Knowledge representation and compilation for symptom-disease-test relationships, IEEE Trans. Biomed. Eng. 36(5): 547-551, 1989.
  2. Masahiko Okada, Minoru Yakata: A method for representing knowledge in laboratory medicine and its application, Proceedings og the 2nd International Federation for Medical and Biological Engineering pan Pacific Symposium, The Australian Federation for Medical & Biological Engineering: Melbourne, pp. 110-111, 1989.
  3. Masahiko Okada, Mihoko Okada, Minoru Yakata: Decomposition of age curves of cancer-mortality rate, MEDINFO 89 (Proceedings of the Sixth World Conference on Medical Informatics, North-Holland: Amsterdam, pp. 765-769, 1989.
  4. Masahiko Okada, Mihoko Okada, Minoru Yakata: Evaluation of arterial pulse wave velocity on the basis of multivariate analysis, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 136-137, 1989.
  5. Masahiko Okada, Minoru Yakata: A new concept for the interpretation of blood chemistry on the basis of stability of measurements. J Clin Comput 18(1): 14-26, 1989. 
  6. Stanley M. Finkelstein, Peter L. N. Kerkhof, Masahiko Okada: Guest editorial, Medical Applications of Artificial Intelligence and Information Systems, IEEE Trans. Biomed Eng 36(5): 501-502, 1989.
  7. Tomomi Kuwana, Osamu Sugita, Masahiko Okada, Minoru Yakata: A combined lectin precipitation method for differentiating modified bone alkaline phosphatase in serum. Clin Chim Acta 185(2): 211-212, 1989.

1988

  1. Masahiko Okada, Taku Nakajima, Noriyuki Eizuka, Yoshiaki Saitoh, Minoru Yakata: Isochronal map of chest wall vibration with cardiokymography. Comput Meth Prog biomed 26(2): 105-114, 1988.
  2. Masahiko Okada: Possible determinants of pulse-wave velocities in vivo, IEEE Trans. Biomed Eng BME 35(5): 357-361, 1988.
  3. Masahiko Okada, Mihoko Okada, Minoru Yakata: A discrimination value of serum lipid level on the basis of healthy and diseased persons. Med Inform 13(2): 81-92, 1988.
  4. Mihoko Okada, Masahiko Okada: Prolog-based system for nursing staff scheduling implemented on a personal computer. Comput Biomed Res 21(1): 53-63. 1988.
  5. Mihoko Okada, Masahiko Okada: A new appoach to the nurse scheduling problem. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 1446-1447, 1988.

1987

  1. Satoshi Kimura, Masahiko Okada: Multivariate Prediction of pathological state with laboratory test results, Proceedings of Symposium of the Clinical Pathology Committee of the Pathological Society of the Republic of China, The Clinical Pathology Committee of the Pathological Society of the Republic of China: Taipei, pp. 26-28, 1987.

1986

  1. Masahiko Okada, Satoshi Kimura, Mihoko Okada: Estimation of arterial pulse wave velocities in frequency domain: method and clinical considerations. Med Biol Eng. Comput 24(3):255-260, 1986.
  2. Masahiko Okada, Mihoko Okada: Portable file management system in FORTRAN: Part 2 The input/output routine for freeformat text. Comput. Meth Prog Biomed 22(2): 199-207, 1986.
  3. Masahiko Okada, Mihoko Okada: An algorithm to manage variable length records for highiy portable clinical database systems. Comput. Biomed Res 19(3): 224-236, 224-236, 1986.
  4. Masahiko Okada, Mihoko Okada: An evaluation of data items for the fiking system of a gastric cancer screening project. Med Inform 11(2): 177-183, 1986.
  5. Mihok Okada, Masahiko Okada: Information management of drug-drug interactions based on foemal representation, IEEE Trans. Syst. Man Cybern CMC 16(3): 358-364, 1986.

1985

  1. Masahiko Okada, Mihoko Okada: An algorithm to count the number of repeated patient data entries with B tree. Comput Biomed Res 18(2): 121-124, 1985.
  2. Masahiko Okada: Storage volume of CT images can be reduced by a factor of five. Comput. Meth. Prog Biomed 20(2): 151-157, 1985.
  3. Masahiko Okada: Noise evaluation and filter design in CT images, IEEE Trans. Biomed Eng BME 32(9): 713-719, 1985.
  4. Masahiko Okada: A program to measure time intervals between R wave peaks in real-time mode. Comput. Meth Prog Biomed 20(3): 235-240, 1985.
  5. Mihoko Okada, Masahiko Okada: A microcomputer-based device for quntitative analysis of alternate pronation and supination of forearms. J Clin Eng 10(2): 157-169, 1985.

1984

  1. Masahiko Okada, Mihoko Okada, Minoru Yakata: Portable file management system in FORTRAN. Comput Prog Biomed 19(1): 47-51, 1984.
  2. Masahiko Okada, Taku Nakajima, Noriyuki Eizuka, Mihoko Okada, Yoshiaki Saito, Kohji Tamura: Computer Animation of chest wall vibration. J Clin Comput 13(1): 16-24, 1984.
  3. Mihoko Okada, Masahiko Okada: The pursuit of a total data processing system free of language and programming. Comput Biomed Res 17(3): 193-207, 1984.

1983

  1. Masahiko Okada: Measurement of speech patterns in neurological disease. Med Biol Eng Comput 21(2): 145-148, 1983.
  2. Masashiko Okada, Mihoko Okada: Is it possible to make a diagnosis in an ambulance?. Jap J Med 22(1): 21-25, 1983.
  3. Masahiko Okada: J. A method for estimating renal functions based on the radioisotope renogram. Comput Biomed Res 16(3): 218-233, 1983.
  4. Masahiko Okada, Mihoko Okada, Minoru Yakata: Scoring method for diagnosis of methylmercury poisoning. J Clin Comput 12(3): 64-76, 1983.
  5. Mihoko Okada, Masahiko Okada: A method for quantification of alternate pronation and supination of forearms. Comput Biomed Res 16(1): 59-78, 1983.

1982

  1. Masahiko Okada, Mihoko Okada.: "Emergency medical care information system: Present and future", in Applications of Computers inMedicine, Ed. M. D. Schwarz, IEEE Press: New York, pp. 224-233, 1982.
  2. Masahiko Okada: Chest wall maps of heart sounds and murmurs Comput Biomed Res 15(3): 281-294, 1982.
  3. Masahiko Okada, Naoshige Maruyama: Software system for real-time discrimination of multiunit nerve impulses. Comput Prog Biomed 14(12): 157-168, 1982.
  4. Masahiko Okada, Mihoko Okada: Hospital selection algorithm for emergency patients. J Clin Comput 11(3): 122-135, 1982.
  5. Mihoko Okada, Masahiko Okada: Microcomputer Software for a facile intellignet terminal. Journal of General Education Department, Niigata University 13: 157-168, 1982.
  6. Kohji Tamura, Masahiko Okada: Three dimensional graphic display of cardiac motion abnormalities in myocardial infarction, Computers in Cardiology (Proceedings of the Computers in Cardiology), IEEE Press: New York, pp. 417-420, 1982.

1981

  1. Masahiko Okada, Mihoko Okada, Naoshige Maruyama, Masao Okada: A new intellingent terminal for clinical computer network. Med Biol Eng Comput 19(3): 257-261, 1981.
  2. Masahiko Okada, Naoshige Maruyama: Software system for real-time discrimination of multi-unit nerve impulses. Comput Prog. Biomed 14(12): 157-164, 1981.
  3. Mihoko Okada, Masahiko Okada: An interactive system for programming free data management and analysis: FLXFL-II, Progress in Health Monitoring (Proceedings of the International Conference on Automatic Multiphasic Health Testing and Services), Excerpta Medica: Amsterdam, pp. 353-361, 1981.

1980

  1. Masahiko Okada, Mihoko Okada, Takato Ooi: Applications of the new computer terminal in the medical environment, MEDINFO 80 (Proceedings of the Third World Conference on Medical Informatics), North-Holland: Amsterdam, pp. 1353,  1980.
  2. Kohji Tmura, Nobuo Furukawa, Yutaka Arai, Hiroshi Murooka, Yoshiaki Saito, Masahiko Okada: Detection of regional cardiac wall-motion abnormalities in myocardial infarction by cardiac wall kymography. Jap Heart J 21(5): 621-632, 1980.
  3. Mihoko Okada, Masahiko Okada: The decentralized software organization in the medical information system - A new microcomputer software for clinical staffs, MEDINFO 80 (Proceedings of the Third World Conference on Medical Informatics), North-Holland: Amsterdam, pp. 728-732, 1980.

1979

  1. Masahiko Okada: A digital filter for the QRS complex detection, IEEE Trans. Biomed. Eng., vol. BME-26, no. 12, pp. 700-703, 1979.
  2. Mihoko Okada, Masahiko Okada: Conversational file processing system FLXFL (FleXible File) for nonprogrammers. Comput Biomed Res 12(4): 335-349, 1979.

1978

  1. Masahiko Okada: A method for clinical data reduction based on "weighted entropy", IEEE Trans. Biomed Eng BME 25(5): 462-467, 1978.

1977

  1. Masahiko Okada, Naoshige Maruyama, Takemasa Kanda, Ken-ichi Shirakawa, Tadashi Katagiri: Medical data base system with an ability of automated diagnosis. Comput Prog Biomed 7(3): 163-170, 1977.

1976

  1. Masahiko Okada: 3-Dimensional graphic display of electrocardiograms. Jpn Circul J 40(3): 167-175, 1976.

TOP

Department of Laboratory Medicine
Niigata University School of Medicine

Publications in English(1976-Present) 

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2011.

  1. Richiro Ishida, Masahiko Okada: Association of Trait Anxiety and Social Desirability with White Blood Cell counts. The Open Psychiatry Journal 5: 1-4, 2011.
  2. Riichiro Ishida, Masahiko Okada: Factors influencing the development of “Purpose in Life” and its relationship to coping with mental stress. Psycology 2(1): 29-34, 2011.
  3. Riichiro Ishida, Tsueko Abe, Masahiko Okada: Firmness of purpose in life significantly influences emotional state and automatic nervous activity. Health 3(8): 507-511, 2011.
  4. Tsueko Abe, Toshinari Aoki Syogo Yata, Masahiko Okada: Sleep duration is significantly associated with carotid artery atherosclerosis incidence in a Japanese population. Atherosclerosis 217: 509-513, 2011.
  5. Michael A. Grandner, Shawn D. Youngstedt: Sleep duration and cardiometabolic risk Commentary on Abe et al., “Sleep duration is significantly associated with carotid artery atherosclerosis incidence in a Japanese population” Atherosclerosis 217: 324-325, 2011.
  6. Toshinari Aoki, Tsueko Abe, Eiji Yamada, Takayuki Matsuto, Masahiko Okada: Increased LDL susceptibility to oxidation accelerates future carotid artery atherosclerosis. Lipids in Health and Disease, in press.
  7. Hirokazu Kawai, Minoru Nomoto, Takeshi Suda, Kenya Kamimura Atsunori Tsuchiya, Yasushi Tamura, Masahiko Yano, Masaki Takamura, Masato Igarashi, Toshifumi Wakai, Satoshi Yamagiwa, Yasunobu Matsuda, Shogo Ohkoshi, Isao Kurosaki, Yoshio Shirai, Masahiko Okada, Yutaka Aoyagi: Multicentric occurrence of hepatocellular carcinoma with nonalcoholic steatohepatitis. World J Gastroenterol 3(1): 15-23, 2011.

2010.

  1. Riichiro Ishida, Masahiko Okada: Association of trait anxiety and social deirability with white blood cell counts. Open Psych J 4: 27-30, 2010.
  2. Tsueko Abe, Akiko Tsuda, Syogo Yata, Tkayuki Matsuto, Masahiko Okada: Hypertension is a major risk factor for future atherosclerotic changes in the lapanese population. Ann Clin Biochem 47: 118-124, 2010.
  3. Yasushi Tamura, Masato Igarashi, Hirokazu Kawai, Takeshi Suda, shinnji Satomura, Yutaka Aoyagi: Clinical Advantage of Highly Sensitive On-Chip Immunoassay for Fucosylated Fraction of Alpha-Fetoprotein in Patients with Hepatocellular Carcinoma. Dig Dis sci Published online: 21 April 2010
  4. Akira Osaki, Tomoyuki Kubota, Takeshi Suda, Masato Igarashi, Keisuke Nagasaki, Atsunori Tsuchiya, Masahiko Yano, Yasushi Tamura, Masaki Takamura, Hirokazu Kawai, Satoshi Yamagiwa, Toru Kikuchi, Minoru Nomoto, Yutaka Aoyagi: Shear wave velocity is a useful marker for managing nonalcoholic steatohepatitis. World J Gastroenterol 16(23): 2918-25, 2010.
  5. Chiba N, Morozumi M, Sunaoshi K, Takahashi S, Takano M, Komori T, Sunakawa K, Ubukata K; IPD Surveillance Study Group. Serotype and antibiotic resistance of isolates from patients with invasive pneumococcal disease in Japan. Epidemiol Infect. 2010 Jan;138(1):61-8.

2009

  1. Masayoshi Masuko, Tatsuo Furukawa, Takashi Abe, Reiko Wada, Soichi Maruyama, Toshiki Kitajima Yasuhiko Shibasaki Ken Toba, Masahiko Okada, Yoshifusa Aizawa: A chronic myeloid leukemia patient with atypical karyotype and BCR-ABL e13a3 transcript caused by complex chromosome rearrangement. Int J Hematol 90: 230-234, 2009.
  2. Takuya Watanabe, Kenji Soga, Haruka Hirono, Katsuhiko Hasegawa, Koichi Shibasaki, Hirokazu Kawai, Yutaka Aoyagi: Features of hepatocellular carcinoma in cases with autoimmune hepatitis and primary biliary cirrhosis.: World J Gastroenterol 15(2):231-239, 2009.
  3. Takeshi Suda, Kenya Kamimura, Tomoyuki Kubota, Yasushi Tamura, Masato Igarashi, Hirokazu Kawai, Yutaka Aoyagi, Dexi Liu: Progress toward liver-based gene therapy. Hepatol Res. 39(4):325-340, 2009.

2008

  1. Elfi Wardaningsih, Takashi Miida, Utako Seino, Yuriko Fueki, Masayuki Ito, Keisuke Nagasaki, Toru Kikuchi, Makoto Uchiyama, Satoshi Hirayama, Osamu Hanyu, Kazunori Miyake, Masahiko Okada: Low adiponectin state is associated with metabolic abnormalities in obese children, particularly depending on apolipoprotein E phenotype. Ann Clin Biochem 45(5): 496-503, 2008.
  2. Shin-ichi Toyabe, Takayuki Matsuto, Tatsuo Ushiki and Kohei Akazawa: Image database and image analysis of chromosome information. Chromosome Nanoscience and Technology, CRC Press, FL, USA, pp.245-257, 2008..
  3. Takashi Miida, Utako Seino, Osamu Miyazaki, Osamu Hanyu, Satoshi Hirayama, Toshikazu Saito, Yuichi Ishikawa, Suguru Akamatsu, Toshimitu Nakano, Katsuyuki Nakajima, Mitsuyo Okazaki, Masahiko Okada: Probucol markedly reduces HDL phospholipids and elevated preβ1-HDL without delayed conversion into α-migrating HDL: Putative role of angiopoietin-like protein 3 in probucol-induced HDL remodeling. Atherosclerosis 200(2): 329-335, 2008.
  4. Hironori Nagasaka, Takashi Miida Kenichi Hirano, Akemi Ota, Tohru Yorifuji, Tomozumi Takatani, Hirokazu Tsukahara, Masaki Takayanagi, Shu-Ping Hui, Kunihiko Kobayashi, and Hitoshi Chiba: Reduced apolipoprotein E-rich high-density lipoprotein level at birth is restored to the normal range in patients with familial hypercholesterolemia in the first year of life. J Clin Endocrinol Metab 93(3): 779-783, 2008.
  5. Riichiro Ishida: Correlations between purpose in life(ikigai) and state anxiety in schizoid temperament with considerations of early life, youth, and adulthood experiences. Acta Med Biol 56(1): 27-32, 2008
  6. Ritsuko Satoh, Hiroki Tsukada, Yoshinari Tanabe, Yukiko Tamura, Tatsuo Yamamoto, Misao Takano, Kyoko Ozaki, Takashi Tamura, Fumitake Gejyo: An autbreak and isolation of drug-resistant Pseudomonas aeruginosa at Niigata University Hospital, Japan. J infect Chmother 14(8): 325-329, 2008.

2007

  1. Takashi Miida, Akihiro Takahashi, Takeshi Ikeuchi: Prevention of stroke and dementia by statin therapy: Experimental and clinical evidence of their pleiotropic effects, Pharmacology & amp. Therapeutics 113(2): 378-393, 2007.
  2. Hironori Nagasaka, Ken-ichi Hirano, Akira Ohtake, Takashi Miida, Tomozumi Takatani, Kei Murayama, Tohru Yorifuji, Kunihiko Kobayashi, Masaki Kanazawa, Atsushi Ogawa, Masaki Takayanagi: Improvements of hypertriglyceridemia and hyperlacticemia in Japanese children with glycogen storage disease type Ia by medium-chain triglyceride milk. European Journal of Pediatrics 166(10): 1009-1016, 2007.
  3. Hironori Nagasaka, Hitoshi Chiba, Shu-Ping Hui, Hazime Takikawa, Takashi Miida, Masaki Takayanagi, Tohru Yorifuji, Makoto Hasegawa, Akemi Ota, Ken-ichi Hirano, Hideaki Kikuchi, Hirokazu Tsukahara, Kunihiko Kobayashi: Depletion of high-density lipoprotein and appearance of triglyceride-rich low-density lipoprotein in a Japanese patient with FIC1 deficiency manifesting benign recurrent intrahepatic cholestasis. Journal of Pediatric Gastroenterology and Nutrition 45(1): 96-105, 2007.
  4. Satoshi Hirayama, Takashi Miida, Osamu Miyazaki, Yoshifusa Aizawa: Preβ1-HDL concentration is a predictor of carotid atherosclerosis in type 2 diabetic patients. Diabetes Care 30(5): 1289-1291, 2007.
  5. Yuriko Fueki, Takashi Miida, Elfi Wardaningsih, Masayuki Ito, Akira Nakamura, Akihiro Takahashi, Osamu Hanyu,Akiko Tsuda, Hisashi Saito, Hitoshi Hama, Masahiko Okada: Regular alcohol consumption improvesinsulin resistance in healthy Japanese men independent of obesity. Clin Chim Acta 382(1-2): 71-76, 2007.
  6. Hiroe Sato, Takashi Miida, Yoko Wada, Mitsuya Mruyama, Shuichi Murakami, Hisashi Hasegawa, Takeshi Kuroda, Ichiei Narita, Fumitake Gejyo: Atherosclerosis is accelerated in well-controlled Systemic Lupus Erythematosus (SLE) even in the premenopausal state, and further exaggerated in the postmenopausal state. Clin Chim Acta. 385(1-2): 35-42, 2007.
  7. Hiroyuki Ebinuma, Takashi Miida, Toshimasa Yamauchi, Yusuke Hada, Kazuo Hara, Naoto Kubota, Takashi Kadowaki: Improved ELISA assay for selective measurements of adiponectin multimers, and identification of adiponectin in human cerebrospinal fluid. Clin Chem 53(8): 1541-1544, 2007.
  8. Osamu Hanyu, Takashi Miida, Keiichiro Kosuge, Takako Ito, Satoshi Soda, Satoshi Hirayama, Elfi Wardaningsih, Yuriko Fueki, Konen Obayashi, Yoshifusa Aizawa: Preheparin lipoprotein lipase mass is a practical marker of insulin resistance in ambulatory type 2 diabetic patients treated with oral hypoglycemic agents. Clin Chim Acta 384(1-2): 118-123, 2007

2006

  1. Richiro Ishida, Masahiko Okada: Effects of a firm purpose in life on anxiety and sympathetic nervous activity caused by emotional stress: assessment by psycho-physiological method. Stress and Health 22: 275-281, 2006.
  2. P. Cao, S. Toyabe, S. Kurashima, M. Okada, K. Akazawa: A modified method of activity-based costing for objectively reducing cost drivers in hospitals. Methods Inf Med 45: 462-469, 2006.
  3. Takashi Miida. The rationale for statin therapy in Alzheimer’s dementia:what we know and what we do not. commentary on the topics of atherosclerosis, International Atherosclerosis Society(http://www.athero.org/comm-index.asp), 2006.
  4. Takashi Miida, Toshiyuki Yamada, Utako Seino, Masayuki Ito, Yuriko Fueki,Akihiro Takahashi, Keiichiro Kosuge, Satoshi Soda, Osamu Hanyu, Konen Obayashi, Osamu Miyazaki, Masahiko Okada: Serum amyloid A (SAA)-induced remodeling of CSF-HDL. Biochim Biophys Acta 1761(4): 424-433, 2006.
  5. Keiichiro Kosuge, Tkashi Miida, Akihiro Takahashi, Konen Obayashi, Masayuki Ito, Takako Ito, Satoshi Soda, KazuyukiOzaki, Satoshi Hirayama, Osamu Hanyu, Yoshifusa Aizawa, Yuichi Nakamura: Estimating the fasting triglyceride concentration from the postprandial HDL cholesterol and apolipoprotein CIII concentrations. Atherosclerosis 184(2): 413-419, 2006.
  6. Kozo Ninomiya, Akihiro Takahashi, Yoshio Fujioka, Yuichi Ishikawa, Mitsuhiro Yokoyama: Transforming growth factor-beta signaling enhances transdifferentiation of macrophages into smooth muscle-like cells. Hypertens Res 29:269-276, 2006.
  7. Hiroshi Okamoto, Yoshio Fujioka, Akihiro Takahashi, Tomosaburo Takahashi, Takahiro Taniguchi, Yuichi Ishikawa, Mitsuhiro Yokoyama: Trichostatin A, an inhibitor of histone deacetylase, inhibits smooth muscle cell proliferation via induction of p21(WAF1). J Atheroscler Thromb 13:183-191, 2006.
  8. Kohei Kamemura, Yoshio Fujioka, Hiroshi Takaishi, Akihiro Takahashi, Takahiro Taniguchi, Yuichi Ishikawa, Mitsuhiro Yokoyama: Chylomicron remnants upregulate CD40 expression via the ERK pathway and a redox-sensitive mechanism in THP-1 cells. Atherosclerosis 187: 257-264, 2006.
  9. Ying Zhu, Jian Yao, Yiman Meng, Ayumi Kasai, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Takashi Miida, Masayuki Takeda, Masahiko Okada, Masanori Kitamura. Profiling of functional phosphodiesterase in mesangial cells using a CRE-SEAP-based reporting system. Br J Pharmacol 148(6): 833-844, 2006.

2005

  1. Masahiko Okada, Tomohiro Saito, Hajime Yoshimura, Yasuhiko Noguchi, Taeko Ito, Hiroko Sasaki, Hitoshi Hama: Surfactant-based homogeneous assay for the Measurement of triglyceride concentrations in VLDL and intermediate-density lipoprotein. Clin Chem 51(10): 1804-1810, 2005.
  2. Ying Zhu, Masahiko Okada, Takayuki Matsuto, Takashi Miida: Prediction of the three-dimensional structure of proteins in the Lipid monolayer on the basis of α-helix bunding the apolipoprotein B-100 structure. Acta Med Biol 53(2): 51-60, 2005.
  3. Takashi Miida, Akihiro Takahashi, Naohito Tanabe, Takeshi Ikeuchi. Can statins really reduce the risk of Alzheimer’s disease and slow its progression? Curr Opin Lipidol 16(6): 619-623, 2005.
  4. Daisuke Saga, Minoru Sakatsume, Asa Ogawa, Yutaka Tsubata, Yoshikatsu Kaneko, Takeshi Kuroda, Fuminori Sato, Junya Ajiro, Daisuke Kondo, Takashi Miida, Ichiei Narita, Fumitake Gejyo: Bezafibrate suppresses rat anti-glomerular basement membrane crescentic glomerulonephritis. Kidney International 67(5): 1821-1829, 2005.
  5. Satoshi Hirayama, Takashi Miida, Konen Obayashi, Fusako Yamazaki, Miho Yamazaki-Sakurai, Masayuki Ito, Yuji Saito, Osamu Hanyu, Katsunori Suzuki, Yoshifusa Aizawa: Effect of apolipoprotein E (apoE) phonotypes on apoE content of CSF-HDL in children. Clin Chim Acta 356(1-2): 110-116, 2005.
  6. Yuuko Takahashi, Yoshio Fujioka, Tomosaburo Takahashi, Kojo Domoto, Akihiro Takahashi, Takahiro Taniguchi, Yuichi Ishikawa, Mitsuhiro Yokoyama: Chylomicron remnants regulate early growth response factor-1 in vascular smooth muscle cells. Life Sci 77: 670-682, 2005
  7. Konen Obayashi, Osamu Hanyu, Takashi Miida, Yukio Ando, Masaaki Nakamura, Ying Zhu, and Masahiko Okada: Circadian rhythm of protein Clin human plasma: Useful marker of autonomic function in liver. Clin Auton Res 15: 57-58, 2005.
  8. Taro Yamashita, Yukio Ando, Shoichi Katsuragi, Masaaki Nakamura, Konen Obayashi, Katsuki Haraoka, Mitsuharu Ueda, Sun Xuguo, Sadahisa Okamoto, and Makoto Uchino: Muscular Amyloid Angiopathy with Amyloidgenic Transthyretin Ser50Ile and Tyr114Cys. Muscle Nerve 31: 41-45, 2005.

2004

  1. Masahiko Okada, Takayuki Matsuto, Takashi Miida, Konen Obayashi, Ying Zhu, and Yuriko Fueki: Lipid analyses for the management of vascular diseases. J Atheroscler Thromb 11(4): 190-199, 2004.
  2. Osamu Sugita, Nobuhito Ishizawa, Takayuki Matsuto, Masahiko Okada, Norihiko Kayahara: A new method of measuring the antioxidant  activity of polyphenols using cumene hydroperoxide. Ann Clin Biochem 41: 72-77, 2004. 
  3. Takashi Miida, Bo Zhang, Konen Obayashi, Utako Seino, Ying Zhu, Takako Ito, Yuichi Nakamura, Masahiko Okada, Keijiro Saku: T13M mutation of lecithin-cholesterol acyltransferase gene causes fish-eye disease. Clin Chim Acta 343(1-2): 201-208, 2004.
  4. Takashi Miida, Konen Obayashi, Utako Seino, Ying Zhu, Takako Ito, Keiichiro Kosuge, Satoshi Hirayama, Osamu Hanyu, Yuichi Nakamura, Toshio Yamaguchi, Takashi Tsuda, Yuji Saito, Osamu Miyazaki, Yasushi Nakamura, Masahiko Okada: LCAT-dependent conversion rate is a determinant of plasma preß1-HDL concentration in healthy Japanese. Clin Chim Acta 350: 107-114, 2004.
  5. Takashi Miida, Satoshi Hirayama, Yuichi Nakamura: Cholesterol-independent effects of statins and its new therapeutic targets: ischemic stroke and dementia. J Atheroscler Thromb 11( 5): 253-264, 2004.
  6. Osamu Hanyu, Takashi Miida, Konen Obayashi, Tomoo Ikarashi T, Satoshi Soda, Susumu Kaneko, Satoshi Hirayama, Katsunori Suzuki, Yuichi Nakamura , Keiichi Yamatani, Yoshifusa Aizawa: Lipoprotein Lipase (LPL) mass in pre-heparin serum reflects insulin sensitivity. Atherosclerosis 174(2): 385-390, 2004.
  7. Konen Obayashi, Yukio Ando, Masaaki Nakamura, Taro Yamashita, Mitsuharu Ueda, Katsuki Haraoka, Hisayasu Terazaki, Makoto Uchino: Near-infrared spectrophotoscopy in assessment of autonomic dysfunction. Neurology 63: 164-166, 2004.
  8. Konen Obayashi, Yukio Ando, Takashi Miida, Masaaki Nakamura, Taro Yamashita, Mitsuharu Ueda, Katsuki Haraoka, Hisayasu Terazaki, Masahiko Okada: Macroscopic assesment of skin venules in patients with familial amyloidotic polyneuropathy (FAP) using near-infrared spectrophotoscopy as a markerof autonomic dysfunction. Amyloid and Amyloidosis. (Gilles G editor), CRC Press 334-336, 2004.
  9. Taro Yamashita, Yukio Ando, Masaaki Nakamura, Konen Obayashi, HisayasuTerazaki, Katsuki Haraoka, Xuguo Sun, Mitsuharu Ueda, Makoto Uchino: Inhibitory effect of α-tocopherol on methylmercury-induced oxidativestress. Environ Health Prev Med 9: 111-117, 2004.

2003

  1. .Pengyu Cao, Masao Hashiba, Kouhei Akazawa, Tomoko Yamakawa, Takayuki Matsuto.: An integrated medical image database and retrieval system using a web application server. Int J Med Inform, 71: 51-55, 2003.
  2. Takashi Miida, Osamu Miyazaki, Osamu Hanyu, Yuichi Nakamura, Satoshi Hirayama, Ichiei Narita, Fumitake Gejyo, Isei Ei, Kazuyuki Tasaki, Yutaka Kohda, Takashi Ohta, Syogo Yata, Isamu Fukamachi Masahiko Okada: LCAT-Dependent Conversion of Preβ1-HDL into α-Migrating HDL is Severely Delayed in Hemodialysis Patients.J Am Soc Nephrol 14: 732-738, 2003.
  3. Takashi Miida, Osamu Miyazaki, Yasushi Nakamura, Satoshi Hirayama, Osamu Hanyu, Isamu Fukamachi, Masahiko Okada: Analytical performance of a sandwich enzyme immunoassay for preβ1-HDL in stabilized plasma. Journal of Lipid Research 44: 645-650, 2003.
  4. Seitaro Maruyama, Kiminori Kato, Makoto Kodama, Yuji Okura, Satoru Hirono, Koichi Fuse, Haruo Hanawa, Osamu Nakagawa, Mikio Nakazawa, Takashi Miida, Eisin Yaoita, Tadashi Yamamoto, Ikuo Inoue, Yoshifusa Aizawa. FR167653 suppresses the progression of experimental autoimmune myocarditis. Mol Cell Biochem 246(1-2): 39-44, 2003. 
  5. Taku Matsubara, Takaharu Ishibashi, Tomoyuki Hori, Kazuyuki Ozaki, Tohru Mezaki, Keiichi Tsuchida, Akimitsu Nasuno, Kaname Kubota, Takayuki Tanaka, Takashi Miida, Yoshifusa Aizawa, Matomo Nishio: Association between coronary endothelial dysfunction and local inflammation of atherosclerotic coronary arteries. Mol Cell Biochem 249(1-2): 67-73, 2003.
  6. Tohru Mezaki, Taku Matsubara, Tomoyuki Hori, Kohtarou Higuchi, Akira Nakamura, Iwao Nakagawa, Shunsuke Imai, Kazuyuki Ozaki, Keiichi Tuchida, Akimitsu Nasuno, Takayuki Tanaka, Kaname Kubota, Masahiko Nakano, Takashi Miida, Yoshifusa Aizawa: Plasma levels of soluble thrombomodulin, C-reactive protein and serum amyloid A protein in the atherosclerotic coronary circulation. Jpn Heart J 44(5): 601-612, 2003.

 

2002

  1. Tomoo Ando, Akira Tanaka, Sadahumi Fukasaku, Ristuko Takada, Masahiko Okada, Kazuhiko Ukai, Kazuhiko Shizuka, Hiroshi Oyamada, Haruo Toda, Tomokazu Taniyama, Tomoaki Usui Makoto Yoshizawa, Tooru Kiryu, Mineo Takagi, Shinya Saida, Takehiko Bando: Pupillary and cardiovascular responses to a video movie in senior human subjects. Auton Neurosc 97: 129-135, 2002.
  2. Takashi Miida, Yuichi. Nakamura, Toru Mezaki, Osamu Hanyu, Seitaro Maruyama, Yoshinori Horikawa, Sachiko Izawa, Yukio Yamada, Hiroshi Matsui and Masahiko Okada: LDL-cholesterol and HDL-cholesterol decrease during the day. Ann Clin Biochem 39:241-249, 2002.
  3. Seitaro Maruyama, Kiminori Kato, Makoto Kodama, Satoru Hirono, Koichi Fuse, Osamu Nakagawa, Mikio Nakazawa, Takashi Miida, Kenichi Watanabe, Tadashi Yamamoto, Yoshifusa Aizawa: Fenofibrate, a peroxisome proliferator-activated receptor α activator, suppresses experimental autoimmune myocarditis by stimulating the interleukin-10 pathway in rats. J Atheroscler Thromb 9(2): 87-92, 2002.
  4. Takahiro Murai, Toshiyuki Ymada, TakashiMida,Katsumitsu Arai, Naoto Endo Tadamasa Hanyu: Fenofibrate inhibits reactive amyloidosis in mice. Arthritis & Rheumatism 46(6): 1683-1688, 2002.

 

2001

  1. Masahiko Okada, Hiroshi Matsui, Yasuki Ito, Akira Fujiwara: Direct measurement of HDL cholesterol: Method Eliminating apolipoprotein E-rich Particles. J Clin Lab Ana 15: 223-229, 2001.
  2. Masahiko Okada, Riichiro Ishida: Direct Measurement of Low-Density-Lipoprotein Cholesterol Is More Effective Than Total Cholesterol for the Purpose of Lipoprotein Screening. Prev Med 32: 224-229, 2001.
  3. Riichiro Ishida, Masahiko Okada: Endurance training in young subjects: Effects on the autonomic nervous system. Acta Medica et Biologica 49(2): 53-60, 2001.
  4. Motohiko Kimura, Yoshihiko Tomita, Tomoyuki Imai, Toshihiro Saito, Akiyoshi Katagiri, Yukie O-hara-Mikami, Takayuki Matsuto, Kota Takahashi: Significance of serum amyloid A on the prognosis in patients with renal cell carcinoma. Cancer 92(8): 2072-2075, 2001.
  5. Minoru Sakatsume, Moritoshi Kadomura, Iku Sakata, Naofumi Imai, Daisuke Kondo, Yutaka Osawa, Hisaki Shimada, Mitsuhiro Ueno, Takashi Miida, Shinichi Nishi, Masaki Akazawa, Fumitake Gejyo: Novel glomerular lipoprotein deposits associated with apolipoprotein E2 homozygosity. Kidney International 59(5): 1911-1918, 2001.
  6. Kouiti Taira, Hideki Bujo, Satoshi Hirayama, Hiroyuki Yamazaki, Tatsuro Kanaki, Kazuo Takahashi, I. Ishii, Takashi Miida, Wolfgang Johann Schneider, Yasushi Saito: LR11, A Mosaic LDL receptor family member, mediates the uptake of apo E-rich lipoproteins in vitro. Arterioscler Thromb Vasc Biol 21(9): 1501-1506, 2001.
  7. Kuniko Okumura-Noji, Kanna Sasai, Renli Zhan, Hitoshi Kawaguchi, Haruhiko Maruyama, Toyohiro Tada, Hikaru Takahashi, Mitsuyo Okazaki, Takashi Miida, N. Sakuma, Genjiro Kimura, Nobuo Ohta, Shinji Yokoyama: Cholesteryl ester transfer protein-deficiency causes slow egg embryonation of Shistosoma japonicum. Biochem Biophys Res Commun 286(2): 305-310, 2001.
  8. H. Takahashi, T. Furukawa, S. Hashimoto, N. Suzuki, T. Kuroha, F. Yamazaki, K. Inano, M. Takahashi, Y. Aizawa, T. Koike: Contribution of TNF-alpha and IL-10 gene polymorphisms to graft-versus-host disease following allo-hematopoietic stem cell transplantation. Bone Marrow Transplant 26: 1317-1323, 2001.
  9. Tatsuo Furukawa, Shigeo Hashimoto, Koichi Inano, Fusako Yamazaki, Hiroko Takeda, Toshio Kakihara, Toshio Yano, Takashi Abe, Wataru Higuchi, Ken Toba, Masuhiro Takahashi, Tadashi Koike, Yoshifusa Aizawa: Analysis of chimerism in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation. Rinsho Ketsueki 42: 488-495, 2001.
  10. Osamu. Miyazaki, Junji. Kobayashi, Isamu. Fukamachi, Takashi. Miida, Hideki. Bujo, Yasushi. Saito: A new sandwich enzyme immunoassay for measurement of plasma pre-β1-HDL levels. J Lipid Res 41(12): 2083-2088, 2001.

2000

  1. Masahiko Okada, Takashi Miida, Hitoshi Hama, Shogo Yata, Takao Sunaga, Akiko Tsuda, Hisashi Saito: Possible risk factors of carotid artery atherosclerosis in the Japanese population: A primary prevention study in non-diabetic subjects. Int Med 39(5): 362-368, 2000.
  2. Masahiko Okada, Takashi Miida, Akira Fujiwara, Noriyoshi Inomata: Autoantibodies against oxidized low-density lipoprotein correlate with Achilles tendon xanthoma. Clin Chem Lab Med 38(6): 501-506, 2000.
  3. Takumi Kurabayashi, Masahiko Okada, Kenichi Tanaka: Eicosapentaenoic acid effect on hyperlipidemia in menopausal Japanese women. Obst Gyne 96(4): 521-528, 2000.
  4. Masao Hashida, Takayuki Matsuto, Futoshi Arai, Tomoko Yamakawa, Kouhei Akazawa: Accessing endoscopic images for remote conference and diagnosis using WWW server with a secure socket layer. Journal of Medical Systems 24(6): 333-338, 2000.
  5. Masao Hashiba, K. Inagawa, Takayuki Matsuto, A. Motonaga, Tomoko Yamakawa, Kouhei Akazawa: Application of the RealAudio package to computerized medical lectures. Med Inform 25(4): 239-245, 2000.
  6. Takashi Miida, Kazuyuki Ozaki, Toru Murakami, Takayuki Kashiwa, Toru Yamadera, Takashi Tsuda, Koichi Inano, Masahiko Okada: Preβ1- high-density lipoprotein (preβ1-HDL) concentration can change with low-density lipoprotein-cholesterol (LDL-C) concentration independent of cholesteryl ester transfer protein (CETP). Clin Chim Acta 292: 69-80, 2000.
  7. Takashi Miida, Katsuyuki Sakai, Kazuyuki Ozaki, Yuichi Nakamura, Toshio Yamaguchi, Takashi Tsuda, Takayuki Kashiwa, Toru Murakami, Koichi Inano, Masahiko Okada: Bezafibrate increases pre β1-HDL at the expense of HDL2 in hypertriglyceriemia. Arterioscler. Thromb Vasc Biol 20(11): 2428-2433, 2000. 
  8. Osamu Miyazaki, Junji Kobayashi, Isamu Fukamachi, Takashi Miida, Hideaki Bujo, Yasushi Saito: A new sandwich enzyme immunoassay for measurement of plasma pre-1-HDL levels. J Lipid Res 41(12): 2083-2088, 2000.
  9. Kouchi Inano, Isao Suetake, Takayuki Ueda, Yasuko Miyake, Masahiko Nakamura, Masahiko Okada, Shoji Tajima: Maintenance-type DNA methyltransferase is highly expressed in post-mitotic neurons and localized in the cytoplasmic compartment. J Biochem 128(2): 315-321, 2000.
  10. Kouchi Inano, Shizuo Tezuka, Takashi Miida, Masahiko Okada: Capillary isotachophoretic analysis of serum lipoproteins using a carrier ampholyte as spacer ion. Ann Clin Biochem 37: 708-716, 2000.
  11. Masahiro Ito, Hidenobu Takahashi, Koichi Fuse, Satoru Hirono, Takashi Washizuka, Kiminori Kato, Fusako Yamazaki, Koichi Inano, Tatsuo Fukukawa, Makoto Komada, Yoshifusa Aizawa: Polymorohisms of tumor necrosis factor-α and interleukin-10genes  in Japanese patients with idiopathic dilated cardiomyopathy. Jap Heart J 41(2): 183-191, 2000.

1999

  1. Masahiko Okada: Conference report: 12th Fall Conference of the Japanese Society of Medical Electronics and Biological Engineering(JSMBE). IFMBE News 36: 6-7, 1999.
  2. Takashi Miida, Fusako Yamazaki, Miho Sakurai, Reiko Wada, Tohru Yamadera, Katsuhisa Asami, Mari Hoshiyama, Atsushi Tanaka, Koichi Inano, Masahiko Okada: The apolipoprotein E content of HDL in cerebrospinal fluid is higher in children than in adults. Clin Chem 45(8): 1294-1296, 1999.
  3. Takashi Miida, Toshiyuki Yamada, Toru Yamadera, Kazuyuki Ozaki, Koichi Inano, Masahiko Okada: Serum amyloid A protein generates pre ß1 high-density lipoprotein from α-migrating high-density lipoprotein. Biochemistry 38(51): 16958-16962, 1999.

1998

  1. Masahiko Okada, Hiroshi Matsui, Yasuki Itoh, Akira Fujiwara, Koichi Inano: Low-density lipoprotein cholesterol can be chemically measured: a new superior method. J Lab Clin Med 132(3): 195-201, 1998.
  2. Masahiko Okada, Marino Hoshiyama: Authors' reply to Letter to the Editor, Oxidation of LDL cholesterol. Ann Clin Biochem 34: 1-2, 1998.
  3. Riichiro Ishida, Masahiko Okada: Effects of physical training on heart rate variability and blood cell counts in healthy adults. Acta Med Biol 46: 139-146, 1998.
  4. Mihoko Okada, Minoru Takaba, Shigekoto Kaihara, Masahiko Okada: Formal representation of summary tables for health care statistical database management. Comput Biomed Res 31: 426-450, 1998.
  5. Takashi Miida, Hideaki Otsuka, Atsushi Tsuchiya, Masahiko Okada: Plasma lipoprotein profiles change significantly during cardiac catheterization. Clin Chem 44(3): 517-521, 1998.
  6. Takashi Miida, Toshio Yamaguchi, Takashi Tsuda, Masahiko Okada: High preβ1-HDL levels in hypercholesterolemia are maintained by probucol but reduced by a low-cholesterol diet. Atherosclerosis 138: 129-134, 1998.
  7. Takashi Ohyama, Hiromi Tsujibayashi, Hideki Tagashira, Koichi Inano, Takayuki Ueda, Yoshiko Hirota, Koichiro Hashimoto: Suppression of electrophoretic anomaly of bent DNA segments by the structural property that causes rapid migration. Nuc Acids Res 26(21): 4811-4817, 1998.

1997

  1. Masahiko Okada, Takayuki Matsuto, Takashi Miida, Koichi Inano: Differences in the effects of cytokines on the expression of adhesion molecules in endothelial cells. Ann Med Int 148(2): 125-129, 1997.
  2. Masahiko Okada, Yasuki Itoh, Koichi Inano, Takashi Miida, Takayuki Matsuto: Structural changes in oxidative modification of low density lipoprotein: investigation by lipid peroxidation products, surface charge, and spetcrophotometric patterns. Ann Clin Biochem 34: 173-178, 1997.
  3. Takashi Miida, Koichi Inano, Toshio Yamaguchi, Takashi Tsuda, Masahiko Okada: Lpa-l levels do not reflect preβ1-HDL levels in human plasma. Atherosclerosis 133: 221-226, 1997.
  4. Toshiyuki Yamada, Takashi Miida: Serum amyloid A remains physiological concentrations in coronary atherosclerosis. Clin.Chem. 43(1): 193, 1997.
  5. T. Asami, K. Inano, T. Miida, T. Kikuchi, M. Uchiyama: Two families of low occulocerebrorenal syndrome with elevated serum HDL levels and CETP gene mutation. Acta Ped 86: 41-46, 1997.
  6. Toshiyuki Yamada, Takashi Miida, Tetsuji Yamaguchi, Yoshihisa Itoh: Effect of serum amyloid A on cellular affinity of low density lipoprotein. Eur J Clin Chem Clin Biochem 35(6): 421-426, 1997.

1996

  1. Masahiko Okada, Takayuki Matsuto, Shuuichi Satoh, Shuuichi Igarashi, Miyako Baba, Osamu Sugita, Mihoko Okada: Role of pulse wave velocity for assessing autonomic nervous system activities in reference to heart rate variability. Med Inf 21(1): 81-90, 1996.
  2. Masahiko Okada: Internet revolutions: present and future of laboratory data communication within and between hospitals, Proceedings of the 7th Asian-Pacific Congress of Clinical Biochemistry: 61-63, 1996.
  3. Masahiko Okada, Osamu Sugita, Takayuki Matsuto, Takashi Miida, Koichi Inano: Endothelial cell damage: the effects of mechanical forces produced by flow division. Cell Eng. 1(4): 183-187, 1996.
  4. Minoru Fukuda, Tetsuya Moroda, Shinichi Toyabe, Tsuneo Iiai, Yasuyuki Kawachi, Hiromi Takahashi-Iwanaga, Toshihiko Iwanaga, Masahiko Okada, Toru Abo: Granulocytosis induced by increasing sympathetic nerve activity contributes to the incidence of acute appendicitis. Biomed Res 17(2): 171-181, 1996.
  5. Takashi Miida, Yuichi Nakamura, Masahiko Okada: Development of coronary atherosclerosis in asymptomatic heterozygous patients with familial hypercholestrolemia. J Cardiol 28(2): 71-77, 1996.
  6. Takashi Miida, Yuichi Nakamura, Koichi Inano, Takayuki Matsuto, Toshio Yamaguchi, Takashi Tsuda, Masahiko Okada: Pre β1-high-density lipoprotein increases in coronary artery disease. Clin Chem 42(12): 1992-1995, 1996.
  7. Toshiyuki Yamada, Takashi Miida, Yoshihisa Itoh, Tadashi Kawai, Merrill D Benson: Characterization of serum amyloid A4 as a plasma apolipoprotein. Clin Chim Acta 251: 105-112, 1996.

1995

  1. Masahiko Okada, Osamu Sugita, Takashi Miida, Takayuki Matsuto, Koichi Inano: Effects of modified low density lipoprotein and hypoxia on the expression of endothelial leukocyte adhesion molecule-1. Eur J Med (La Presse Medicale), 24(10): 483-488, 1995.
  2. Satoshi Kimura, Osamu Sugita, Takayuki Matsuto, Masahiko Okada, Yasuyuki Igarashi: HPLC application for phosphoinositides analyses of A431 cells and human platelets. Acta Med Biol 43(1): 59-62, 1995.
  3. Osamu Sugita, Yae Tomiyama, Takayuki Matsuto, Masahiko Okada, Fumitake Gejo, Masaaki Arakawa, S.Takahashi, Y.Watazu, N.Kaneda: A new enzymatic method for the determination of inulin. Ann Clin Biochem 32: 561 -565, 1995.
  4. Takayuki Nemoto, Tomonori Matsuzaka, Minoru Ota, Yuko Ohara-Nemoto, Masaru Kaneko, Tsuneyoshi Horigome Koichi Inano: Kinship between self -oligomerizing and the estrogen receptor interacting activities of the 90- kDa heat shock protein. Steroid Biochem (Life Sci. Ady. ): 59-67, 1995.

1994

  1. Masahiko Okada, Takayuki Matsuto, Osamu Sugita, Satoshi Kimura, Hideaki Matsumoto, Tokuhiro Okada: A simple method to measure red blood cell deformability by centrifugation. Eur J Med (La Presse Medicale) 23(5): 1613-1615, 1994.
  2. Masahiko Okada, Osamu Sugita, Takashi Miida, Yuko Makino, Noriko Komoro: Endothelial cell responses to controlled pulsatile flow at the bifurcation of a model vessel. 16th Annual International Conference of the IEEE/EMBS 1: 291-292, 1994.
  3. Toshiyuki Yadada, Toshihiko Kakihara, Fumitake Gejyo, Masahiko Okada: A monoclonal antibody recognizing apolipoprotein E peptides in systemic amyloid deposits. Ann Clin Lab 24(3), 1994.
  4. Kouichi Inano, Sylvia W. Curtis, Kenneth S. Korach, Saburo Omata, Tsuneyoshi Horigome: Heat shock protein 90 strongly stimulates the binding of purified estrogen receptor to its responsive element. J Biochem 116(4): 759-766, 1994.
  5. Toshiyuki Yamada, Barbara Kluve-Beckerman, William M. kuster, Juris J. Liepnieks Merrill D. Benson: Measurement of serum amyloid A4(SAA4): its constitutive presence in serum. Int J Exp Clin Invest 1: 114-118, 1994.
  6. Toshiyuki Yamada, Barbara Kluve-Beckerman, Juris J. Liepnieks Merrill D. Benson: Fibril formation from recombinant human serum amyloid A. Amiloid Biochimica et Biophysica Acta 1266: 323-329, 1994.

1993

  1. Masahiko Okada, Osamu Sugita, Yuko Makino, Takayuki Matsuto, Lan Hongxing: A system for generating pulsatile flow and shear stress to investigate cultured vascular cell functions. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. 15, IEEE Press: New York, pp. 922-923, 1993.
  2. Mihoko Okada, Myles O'Brien, Masahiko Okada: IntroStat: a Hypertext-based electronic textbook to introduce fundamental methods of biomedical statistics. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society  15, IEEE Press: New York, pp. 634-635, 1993.
  3. Toshiyuki Yamada, Yasuhiro Nomata, Osamu Sugita, Masahiko Okada: A rapid method for measuring serum amyloid A protein by latex agglutination nephelometric immunoassay. Ann Clin Biochem 30: 72-76, 1993.
  4. Toshiyuki Yamada, Osamu Sugita, Masahiko Okada, Takayuki Matsuto: Use of chemiluminescent acridinium ester label for cellular uptake assay of low density lipoprotein. Ann Clin Biochem 30: 490-491, 1993.
  5. Tetsuo Nakayama, Satomi Sonoda, Takashi Urano, Toshiyuki Yamada, Masahiko Okada: Monitoring both serum amyloid protein A and C-reactive protein as inflammatory markers in infection diseases. Clin Chem 39(2): 293-297, 1993.
  6. Hiroyuki Miwata, Toshiyuki Yamada, Masahiko Okada, Toyoichiro Kudo, Hiroshi Kimura, Tsuneo Morishima: Serum amyloid A protein in acute viral infections. Arch. Dis. Child. 68: 210-214, 1993.
  7. Mikihiko Kawano, Takashi Miida, Christopher J. Fielding, Phoebe E. Fielding: Quantitation of prebeta-HDL dependent and nonspecific components of the total efflux of cellular cholesterol and phospholipid. Biochemistry 32: 5025- 5028, 1993.

1992

  1. Mihoko Okada, Masahiko Okada, Hideo Tohma, Akinori, Hisashige, Tetsuo Kawamura, Koji Yamamoto: A study on appropriate allocation of comedical staff in hospital. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 1150-1151, 1992.
  2. Osamu Sugita, Toshiyuki Yamada, Masahiko Okada, Kunio Takeuchi: Reference values of serum and urine creatinine, and of creatinine clearnace by a new enzymatic method. Ann Clin Biochem 29: 523-528, 1992.
  3. Osamu Sugita, Toshiyuki Yamada, Takayuki Matsuto, Masahiko Okada: Preparation of LDL from dextran-sulfate cellulose column after plasmapheresis. Progress in Clinical Biochemistry, Excerpta Medica: Tokyo, pp. 467-468, 1992.
  4. Takashi. Miida, M. Kawano, C.J. Fielding, P.E. Fielding: Regulation of the concentration of prebeta high-density lipoprotein in normal plasma by cell membranes and lecithin-cholesterol acyltranferase activity. Biochemistry 31(45): 11112-11117, 1992.
  5. Koichi Inano, Takehiko Ishida, Saburo Omata, Tsuneyoshi Horigome: In Vitro formation of estrogen receptor-heat shock protein 90 complexes. J Biochem 112(4): 535- 540, 1992.
  6. Satoshi Kimura, Shigeyuki Kawa, Fugiang Ruan, Mohammad Nisar, Yoshito Sadahira, Sen-Itiroh Hakomori, Yasuyuki Igarashi: Effect of sphingosine and its N-methyl derivatives on oxidative burst, phagokinenetic activity, and trans-endothelial migration of human neutrophils. Biochemical Pharmacology 44(8): 1858-1595, 1992.

1991

  1. Masahiko Okada: A method to evaluate arterial pulse wave velocity by age and blood pressure. J. Clin. Comput. 20(1): 1-20, 1991.
  2. Masahiko Okada,  Mihoko Okada: The pursuit of a portable clinical data base system written by FORTRAN, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 1212-1213, 1991.
  3. Masahiko Okada: Usefulness of daily patients data for monitoring laboratory test results, Quality Control in the Clinical Laboraotry '91, Excerpta Medica: Tokyo, pp. 289-300, 1991.
  4. Phoebe E. Fielding, Takashi Miida, Christopher J. Fielding: Metabolism of low-density lipoprotein free cholesterol by human plasma lecithin-cholesterol acyltransferase. Biochemistry 30(35): 8551-8557, 1991.
  5. Masahide Yamamoto, Yoshiaki Takahashi, Koichi Inano, Tsuneyoshi Horigome, Hiroshi Sugano: Characterization of the hydrophobic region of heat shock protein 90. J. Biochem. 110(1): 141-145, 1991.
  6. Tomomi Kuwana, Osamu Sugita, Minoru Yakata: Sugar chain heterogeneity of bone and liver alkaline phosphatase in serum. Enzyme 45: 63-66, 1991.
  7. Hirofumi Okoshi, Sen-itiroh Hakomori, Mohammad Nisar, Qinghong Zhou, Satoshi Kimura, et al: Cell membrane signaling as target in cancer therpy II: inhibitory effect of N, N, N-trimethylsphingosine on metastatic potential of murine B16 melanoma cell line through blocking of tumor cell-dependent platelet aggregation. Cancer Research 51(15): 6019-6024, 1991.
  8. S. Kimura, D. Saitou, A. Singhal, S. Hakomori: Diagnostic and prognostic significance for early stage lung cancer by cytological sputum examination with anti-carbohydrate monoclonal anti-bodies. Glycoconjugate J. 8(3): 178, 1991.

1990

  1. Masahiko Okada: Arterial pulse wave velocity as a meausre of cardiovascular stress, proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 550-551, 1990.
  2. Masahiko Okada: Method for quality control of laboratory tests using histograms of daily patient data. J. Clin. Comput. 18(5), (6): 120-129, 1990.
  3. Kazuo Hikosaka, Takayuki Matsuto, et al: Three regions in the anterior bank of the caudal superior temporal sulcus of the macaque monkey. Vision, Memory, and the Temporal Lobe: 347-353, 1990.
  4. Takayuki Matsuto, et al: Laboratory test scheduling based on constraint propagation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society 12(3), 1990.
  5. Kouichi Inano, Makoto Haino, Masaomi Iwasaki, Naomi Ono, Tsuneyoshi Horigome, Hiroshi Sugano: Reconstitution of the 9S estrogen receptor with heat shokck protein 90. FEBS Letters 267(1): 157-159, 1990.
  6. Tomomi Kuwana, and Sidney B. Rosalki: Intestinal variant alkaline phosphatase in plasma in disease. Clin Chem 36(11): 1918-1921, 1990.

1989

  1. Masahiko Okada, Mihoko Okada: Knowledge representation and compilation for symptom-disease-test relationships, IEEE Trans. Biomed. Eng. 36(5): 547-551, 1989.
  2. Masahiko Okada, Minoru Yakata: A method for representing knowledge in laboratory medicine and its application, Proceedings og the 2nd International Federation for Medical and Biological Engineering pan Pacific Symposium, The Australian Federation for Medical & Biological Engineering: Melbourne, pp. 110-111, 1989.
  3. Masahiko Okada, Mihoko Okada, Minoru Yakata: Decomposition of age curves of cancer-mortality rate, MEDINFO 89 (Proceedings of the Sixth World Conference on Medical Informatics, North-Holland: Amsterdam, pp. 765-769, 1989.
  4. Masahiko Okada, Mihoko Okada, Minoru Yakata: Evaluation of arterial pulse wave velocity on the basis of multivariate analysis, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 136-137, 1989.
  5. Masahiko Okada, Minoru Yakata: A new concept for the interpretation of blood chemistry on the basis of stability of measurements. J Clin Comput 18(1): 14-26, 1989. 
  6. Stanley M. Finkelstein, Peter L. N. Kerkhof, Masahiko Okada: Guest editorial, Medical Applications of Artificial Intelligence and Information Systems, IEEE Trans. Biomed Eng 36(5): 501-502, 1989.
  7. Tomomi Kuwana, Osamu Sugita, Masahiko Okada, Minoru Yakata: A combined lectin precipitation method for differentiating modified bone alkaline phosphatase in serum. Clin Chim Acta 185(2): 211-212, 1989.

1988

  1. Masahiko Okada, Taku Nakajima, Noriyuki Eizuka, Yoshiaki Saitoh, Minoru Yakata: Isochronal map of chest wall vibration with cardiokymography. Comput Meth Prog biomed 26(2): 105-114, 1988.
  2. Masahiko Okada: Possible determinants of pulse-wave velocities in vivo, IEEE Trans. Biomed Eng BME 35(5): 357-361, 1988.
  3. Masahiko Okada, Mihoko Okada, Minoru Yakata: A discrimination value of serum lipid level on the basis of healthy and diseased persons. Med Inform 13(2): 81-92, 1988.
  4. Mihoko Okada, Masahiko Okada: Prolog-based system for nursing staff scheduling implemented on a personal computer. Comput Biomed Res 21(1): 53-63. 1988.
  5. Mihoko Okada, Masahiko Okada: A new appoach to the nurse scheduling problem. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, IEEE Press: New York, pp. 1446-1447, 1988.

1987

  1. Satoshi Kimura, Masahiko Okada: Multivariate Prediction of pathological state with laboratory test results, Proceedings of Symposium of the Clinical Pathology Committee of the Pathological Society of the Republic of China, The Clinical Pathology Committee of the Pathological Society of the Republic of China: Taipei, pp. 26-28, 1987.

1986

  1. Masahiko Okada, Satoshi Kimura, Mihoko Okada: Estimation of arterial pulse wave velocities in frequency domain: method and clinical considerations. Med Biol Eng. Comput 24(3):255-260, 1986.
  2. Masahiko Okada, Mihoko Okada: Portable file management system in FORTRAN: Part 2 The input/output routine for freeformat text. Comput. Meth Prog Biomed 22(2): 199-207, 1986.
  3. Masahiko Okada, Mihoko Okada: An algorithm to manage variable length records for highiy portable clinical database systems. Comput. Biomed Res 19(3): 224-236, 224-236, 1986.
  4. Masahiko Okada, Mihoko Okada: An evaluation of data items for the fiking system of a gastric cancer screening project. Med Inform 11(2): 177-183, 1986.
  5. Mihok Okada, Masahiko Okada: Information management of drug-drug interactions based on foemal representation, IEEE Trans. Syst. Man Cybern CMC 16(3): 358-364, 1986.

1985

  1. Masahiko Okada, Mihoko Okada: An algorithm to count the number of repeated patient data entries with B tree. Comput Biomed Res 18(2): 121-124, 1985.
  2. Masahiko Okada: Storage volume of CT images can be reduced by a factor of five. Comput. Meth. Prog Biomed 20(2): 151-157, 1985.
  3. Masahiko Okada: Noise evaluation and filter design in CT images, IEEE Trans. Biomed Eng BME 32(9): 713-719, 1985.
  4. Masahiko Okada: A program to measure time intervals between R wave peaks in real-time mode. Comput. Meth Prog Biomed 20(3): 235-240, 1985.
  5. Mihoko Okada, Masahiko Okada: A microcomputer-based device for quntitative analysis of alternate pronation and supination of forearms. J Clin Eng 10(2): 157-169, 1985.

1984

  1. Masahiko Okada, Mihoko Okada, Minoru Yakata: Portable file management system in FORTRAN. Comput Prog Biomed 19(1): 47-51, 1984.
  2. Masahiko Okada, Taku Nakajima, Noriyuki Eizuka, Mihoko Okada, Yoshiaki Saito, Kohji Tamura: Computer Animation of chest wall vibration. J Clin Comput 13(1): 16-24, 1984.
  3. Mihoko Okada, Masahiko Okada: The pursuit of a total data processing system free of language and programming. Comput Biomed Res 17(3): 193-207, 1984.

1983

  1. Masahiko Okada: Measurement of speech patterns in neurological disease. Med Biol Eng Comput 21(2): 145-148, 1983.
  2. Masashiko Okada, Mihoko Okada: Is it possible to make a diagnosis in an ambulance?. Jap J Med 22(1): 21-25, 1983.
  3. Masahiko Okada: J. A method for estimating renal functions based on the radioisotope renogram. Comput Biomed Res 16(3): 218-233, 1983.
  4. Masahiko Okada, Mihoko Okada, Minoru Yakata: Scoring method for diagnosis of methylmercury poisoning. J Clin Comput 12(3): 64-76, 1983.
  5. Mihoko Okada, Masahiko Okada: A method for quantification of alternate pronation and supination of forearms. Comput Biomed Res 16(1): 59-78, 1983.

1982

  1. Masahiko Okada, Mihoko Okada.: "Emergency medical care information system: Present and future", in Applications of Computers inMedicine, Ed. M. D. Schwarz, IEEE Press: New York, pp. 224-233, 1982.
  2. Masahiko Okada: Chest wall maps of heart sounds and murmurs Comput Biomed Res 15(3): 281-294, 1982.
  3. Masahiko Okada, Naoshige Maruyama: Software system for real-time discrimination of multiunit nerve impulses. Comput Prog Biomed 14(12): 157-168, 1982.
  4. Masahiko Okada, Mihoko Okada: Hospital selection algorithm for emergency patients. J Clin Comput 11(3): 122-135, 1982.
  5. Mihoko Okada, Masahiko Okada: Microcomputer Software for a facile intellignet terminal. Journal of General Education Department, Niigata University 13: 157-168, 1982.
  6. Kohji Tamura, Masahiko Okada: Three dimensional graphic display of cardiac motion abnormalities in myocardial infarction, Computers in Cardiology (Proceedings of the Computers in Cardiology), IEEE Press: New York, pp. 417-420, 1982.

1981

  1. Masahiko Okada, Mihoko Okada, Naoshige Maruyama, Masao Okada: A new intellingent terminal for clinical computer network. Med Biol Eng Comput 19(3): 257-261, 1981.
  2. Masahiko Okada, Naoshige Maruyama: Software system for real-time discrimination of multi-unit nerve impulses. Comput Prog. Biomed 14(12): 157-164, 1981.
  3. Mihoko Okada, Masahiko Okada: An interactive system for programming free data management and analysis: FLXFL-II, Progress in Health Monitoring (Proceedings of the International Conference on Automatic Multiphasic Health Testing and Services), Excerpta Medica: Amsterdam, pp. 353-361, 1981.

1980

  1. Masahiko Okada, Mihoko Okada, Takato Ooi: Applications of the new computer terminal in the medical environment, MEDINFO 80 (Proceedings of the Third World Conference on Medical Informatics), North-Holland: Amsterdam, pp. 1353,  1980.
  2. Kohji Tmura, Nobuo Furukawa, Yutaka Arai, Hiroshi Murooka, Yoshiaki Saito, Masahiko Okada: Detection of regional cardiac wall-motion abnormalities in myocardial infarction by cardiac wall kymography. Jap Heart J 21(5): 621-632, 1980.
  3. Mihoko Okada, Masahiko Okada: The decentralized software organization in the medical information system - A new microcomputer software for clinical staffs, MEDINFO 80 (Proceedings of the Third World Conference on Medical Informatics), North-Holland: Amsterdam, pp. 728-732, 1980.

1979

  1. Masahiko Okada: A digital filter for the QRS complex detection, IEEE Trans. Biomed. Eng., vol. BME-26, no. 12, pp. 700-703, 1979.
  2. Mihoko Okada, Masahiko Okada: Conversational file processing system FLXFL (FleXible File) for nonprogrammers. Comput Biomed Res 12(4): 335-349, 1979.

1978

  1. Masahiko Okada: A method for clinical data reduction based on "weighted entropy", IEEE Trans. Biomed Eng BME 25(5): 462-467, 1978.

1977

  1. Masahiko Okada, Naoshige Maruyama, Takemasa Kanda, Ken-ichi Shirakawa, Tadashi Katagiri: Medical data base system with an ability of automated diagnosis. Comput Prog Biomed 7(3): 163-170, 1977.

1976

  1. Masahiko Okada: 3-Dimensional graphic display of electrocardiograms. Jpn Circul J 40(3): 167-175, 1976.

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