Examination in Renal Pathology in 1999

Question

Complete the following sentences which state pathological features of the kidney disease by filling in the proper words in the blanks as an example.

Example: Poststreptococcal acute glomerulonephritis

[1] By light microscopy ( polymorphonuclear leukocytes ) are predominant in the glomerular capillaries as accumulating leukocytes.

[2] By immunofluorescent microscopy granular deposition of IgG and complement components is detected along the (glomerular capillary wall).

[3] Large electron-dense deposits called (hump) are demonstrated between the glomerular epithelial cell and the glomerular basement membrane by electron microscopy.

(1) Diabetic nephropathy

[1] Hyaline degeneration observed in vascular wall of (afferent arterioles) and (efferent arterioles) by light microscopy is characteristic for the disease.

[2] The nodular lesion characteristic for the disease is also called (Kimmelstiel-Wilson) lesion by taking the names of discoverers.

[3] The diffuse lesion, characterized by thickening of (glomerular basement membrane) is observed generally observed by electron microscopy in the glomerulus of diabetic nephropathy.

　

(2) Type I membranoproliferative glomerulonephritis

[1] Doubling of glomerular basement membrane observed in PAM-stained section of the kidney with this disease is called (double contour or tram-track appearance) in English.

[2] Immunofluorescence microscopy shows deposition of IgG and complement components along the (glomerular basement membrane) in a fringeﾓ pattern.

[3] Insertion of (mesangial cell) cytoplasm is often observed between the doubled glomerular basement membrane by electron microscopy.

　

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