{"id":6246,"date":"2024-10-17T13:37:24","date_gmt":"2024-10-17T04:37:24","guid":{"rendered":"https:\/\/www.med.niigata-u.ac.jp\/pub\/?p=6246"},"modified":"2024-10-18T13:23:57","modified_gmt":"2024-10-18T04:23:57","slug":"2022-2023%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%b5%e3%83%bc-2","status":"publish","type":"post","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2024\/10\/17\/2022-2023%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%b5%e3%83%bc-2\/","title":{"rendered":"2022-2023\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\uff082024\u5e7410\u670817\u65e5\u66f4\u65b0\uff09"},"content":{"rendered":"<p><span style=\"font-size: 14pt;\"><strong>2022-2023\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6d41\u884c\u682a\u3068\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u85ac\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u6982\u8981\uff082024\u5e7410\u670817\u65e5\u66f4\u65b0\uff09<\/strong><\/span><\/p>\n<p>2022\u5e7410\u6708\u304b\u30892023\u5e749\u6708\u307e\u3067\u306e\u671f\u9593\u4e2d\u3001\u65e5\u672c\u5404\u5730\u3067\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u6d41\u884c\u52d5\u5411\u3068\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u304a\u3088\u3073\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u306b\u5bfe\u3059\u308b\u85ac\u5264\u8010\u6027\u5909\u7570\u3092\u6301\u3064\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306e\u767a\u751f\u72b6\u6cc1\u306b\u3064\u3044\u3066\u8abf\u3079\u307e\u3057\u305f\u3002<\/p>\n<p>\u5168\u56fd7\u770c\u306e8\u3064\u306e\u5916\u6765\u533b\u7642\u6a5f\u95a2\u304c\u7814\u7a76\u306b\u53c2\u52a0\u3057\u307e\u3057\u305f\uff08\u56f31\uff09\u3002\u533b\u7642\u6a5f\u95a2\u3092\u53d7\u8a3a\u3057\u3001\u8fc5\u901f\u8a3a\u65ad\u30c6\u30b9\u30c8\u30ad\u30c3\u30c8\uff08RDT\uff09\u3067\u967d\u6027\u3068\u5224\u5b9a\u3055\u308c\u305f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u69d8\u75be\u60a3\uff08ILI\uff09\u60a3\u8005\u304b\u3089\u3001\u4e0a\u6c17\u9053\u30b9\u30ef\u30d6\u3092\u691c\u4f53\u3068\u3057\u3066\u53ce\u96c6\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u81e8\u5e8a\u691c\u4f53\u306f\u5168\u3066\u65b0\u6f5f\u5927\u5b66\u306b\u9001\u3089\u308c\u3001RT-PCR\u6cd5\u3067\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306e\u691c\u51fa\u3068\u578b\/\u4e9c\u578b\u306e\u6c7a\u5b9a\u3092\u884c\u3044\u307e\u3057\u305f\u3002\u63a1\u53d6\u3055\u308c\u305f297\u4ef6\u306e\u691c\u4f53\u306e\u3046\u3061\u3001248\u4ef6\uff0883.5\uff05\uff09\u304c\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9A(H3N2)\u300125\u4ef6\uff088.4\uff05\uff09\u304c\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9A(H1N1)pdm09\u300110\u4ef6\uff083.4\uff05\uff09\u304c\u4e9c\u578b\u5224\u5b9a\u4e0d\u80fd\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9A\u578b\u300114\u4ef6\u304cRT-PCR\u6cd5\u3067\u9670\u6027\u3067\u3057\u305f\uff08\u56f31\u3001\u88681\uff09\u3002<\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/01.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6249\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/01-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/01-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/01-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/01.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/03.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6257\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/03-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/03-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/03-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/03.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u304c\u691c\u51fa\u3055\u308c\u305f\u60a3\u8005\u6570\u3092\u691c\u4f53\u63a1\u53d6\u3057\u305f\u65e5\u3092\u3082\u3068\u306b\u9031\u6bce\u306b\u96c6\u8a08\u3057\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u75ab\u5b66\u66f2\u7dda\u3092\u4f5c\u6210\u3057\u307e\u3057\u305f\u3002\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u6d41\u884c\u306f2022\u5e74\u672b\u306b\u59cb\u307e\u308a\u30012023\u5e741\u6708\u306b\u30d4\u30fc\u30af\u306b\u9054\u3057\u30013\u6708\u306b\u5c0f\u898f\u6a21\u306a\u30d4\u30fc\u30af\u304c\u518d\u5ea6\u767a\u751f\u3057\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u6d41\u884c\u306f3\u6708\u304b\u30899\u6708\u307e\u3067\u4f4e\u3044\u30ec\u30d9\u30eb\u3067\u7d9a\u304d\u307e\u3057\u305f\uff08\u56f32\uff09\u3002\u65e5\u672c\u5404\u5730\u3067\u4e3b\u306bA(H3N2)\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u304c\u6d41\u884c\u3057\u307e\u3057\u305f\u304c\u3001A(H1N1)pdm09\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u3082\u65b0\u6f5f\u3001\u6771\u4eac\u3001\u5c71\u53e3\u3001\u6c96\u7e04\u3067\u5c11\u6570\u691c\u51fa\u3055\u308c\u307e\u3057\u305f\uff08\u56f31\u30012\uff09\u3002<\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/02.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6250\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/02-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/02-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/02-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/02.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>\u85ac\u5264\u8010\u6027\u30de\u30fc\u30ab\u30fc\u3068\u306a\u308b\u5909\u7570\uff08\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u4f4e\u4e0b\u5909\u7570\u306ePA\/I38T\u5909\u7570\u3001\u304a\u3088\u3073\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u306b\u5bfe\u3059\u308b\u8010\u6027\u5909\u7570\u306eNA\/H275Y\uff09\u306b\u3064\u3044\u3066RT-PCR\u6cd5\u3067\u691c\u51fa\u3057\u3001\u7d9a\u3044\u3066\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b7\u30f3\u30b0\uff08NGS\uff09\u304a\u3088\u3073\u30b5\u30f3\u30ac\u30fc\u6cd5\u306b\u3088\u308aPA\u907a\u4f1d\u5b50\u3068NA\u907a\u4f1d\u5b50\u306b\u307f\u3089\u308c\u308b\u85ac\u5264\u611f\u53d7\u6027\u4f4e\u4e0b\u5909\u7570\u3092\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\u521d\u8a3a\u6642\u306b1\u56de\u76ee\u306e\u691c\u4f53\u3092\u63a1\u53d6\u3057\u3001\u3055\u3089\u306b\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u53c8\u306f\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u6295\u85ac\u6cbb\u7642\u5f8c\u30013\uff0d7\u65e5\u5f8c\u306b\u518d\u53d7\u8a3a\u3057\u305f\u969b\u306b2\u56de\u76ee\u306e\u691c\u4f53\u3092\u63a1\u53d6\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>RT-PCR\u6cd5\u306b\u3088\u308a\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u306b\u5bfe\u3057\u85ac\u5264\u611f\u53d7\u6027\u4f4e\u4e0b\u3092\u793a\u3059PA\/I38T\u5909\u7570\u304c\u3001\u521d\u8a3a\u6642\u306b\u63a1\u53d6\u3055\u308c\u305f248\u4ef6\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6A(H3N2)\u306e\u3046\u30612\u4ef6\u3067\u691c\u51fa\u3055\u308c\u3001\u305d\u306e\u983b\u5ea6\u306f0.8\uff05\uff082\/248\uff09\u3067\u3057\u305f\uff08\u88682\uff09\u3002NGS\u306b\u3088\u308aPA\u907a\u4f1d\u5b50\u5909\u7570\u306e\u78ba\u8a8d\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001RT-PCR\u6cd5\u3068\u540c\u69d8\u306b2\u4ef6\u304b\u3089PA\/I38T\u5909\u7570\u3092\u691c\u51fa\u3057\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u305d\u306e\u4ed6\u306ePA\u5909\u7570\u682a\u306f\u78ba\u8a8d\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\uff080.8%\u30012\/248\uff09\u3002\u306a\u304a\u3001\u521d\u8a3a\u6642\u306b\u63a1\u53d6\u3055\u308c\u305f25\u4ef6\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6A(H1N1)pdm09\u304b\u3089\u3001PA\u5909\u7570\u682a\u306f\u3001RT-PCR\u6cd5\u3068NGS\u5171\u306b\u691c\u51fa\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u88682\uff09\u3002<\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/04.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6252\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/04-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/04-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/04-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/04.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u6295\u85ac\u6cbb\u7642\u5f8c\u306e\u518d\u8a3a\u6642\u306e\u60a3\u8005\u691c\u4f53\u306b\u304a\u3051\u308bRT-PCR\u6cd5\u306b\u3088\u308bPA\/I38T\u5909\u7570\u306e\u691c\u51fa\u3067\u306f\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6A(H3N2)\u967d\u6027\u60a3\u800554\u540d\u306e\u3046\u30616\u540d\u304b\u3089\u691c\u51fa\u3055\u308c\u305f\u305f\u3081\u3001\u51fa\u73fe\u983b\u5ea6\u306f11.1\uff05\uff086\/54\uff09\u3068\u306a\u308a\u307e\u3057\u305f\uff08\u88682\uff09\u3002\u3061\u306a\u307f\u306b\u6295\u85ac\u5f8c\u518d\u8a3a\u6642\u306e\u691c\u4f53\u304cRT-PCR\u6cd5\u3067\u967d\u6027\u3068\u306a\u3063\u305f21\u4f8b\u3092\u5206\u6bcd\u3068\u3057\u305f\u5834\u5408\u306b\u306f\u3001PA\/I38T\u5909\u7570\u682a\u306e\u983b\u5ea6\u306f28.6\uff05\uff086\/21\uff09\u306b\u4e0a\u6607\u3057\u307e\u3057\u305f\u3002\u540c\u3058\u691c\u4f53\u3067\u3001NGS\u89e3\u6790\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u85ac\u5264\u8010\u6027\u306b\u95a2\u4fc2\u3059\u308bPA\u5909\u7570\u304c\u6295\u85ac\u5f8c\u306e\u691c\u4f53\u304b\u30898\u4ef6\u898b\u3064\u304b\u308a\u307e\u3057\u305f\uff0814.8%\u30018\/54\uff09\uff08\u88682\uff09\u3002\u305d\u306e\u5909\u7570\u306e\u5185\u8a33\u306f\u3001PA\/I38T\u5909\u7570\u304c4\u4ef6\u3001PA\/I38M\u5909\u7570\u304c1\u4ef6\u3001PA\/I38M\/T\u304a\u3088\u3073PA\/E23K+I38T\u3001PA\/E23G+I38T\u306e\u6df7\u5408\u5909\u7570\u304c\u305d\u308c\u305e\u308c1\u4ef6\u305a\u3064\u3067\u3057\u305f\u3002\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u6295\u85ac\u5f8c\u306b\u63a1\u53d6\u3055\u308cNGS\u307e\u305f\u306fRT-PCR\u6cd5\u306b\u3088\u308b\u89e3\u6790\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f21\u691c\u4f53\u3092\u6bcd\u6570\u3068\u3059\u308b\u3068\u3001\u983b\u5ea6\u306f38.1\uff05\uff088\/21\uff09\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u3067\u6cbb\u7642\u3055\u308c\u305f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6A(H1N1)pdm09\u60a3\u80051\u540d\u306e\u6295\u85ac\u5f8c\u691c\u4f53\u306b\u3001PA\u5909\u7570\u306fRT-PCR\u6cd5\u3001NGS\u5171\u306b\u691c\u51fa\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f (0\/1) \uff08\u88682\uff09\u3002<\/p>\n<p>\u30b5\u30f3\u30ac\u30fc\u6cd5\u306b\u3088\u308b\u30c0\u30a4\u30ec\u30af\u30c8\u30b7\u30fc\u30b1\u30f3\u30b9\u89e3\u6790\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f275\u691c\u4f53\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306b\u5bfe\u3057\u3001\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u306e\u611f\u53d7\u6027\u4f4e\u4e0b\u306b\u95a2\u4e0e\u3059\u308bPA\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u3064\u3044\u3066\u89e3\u6790\u3057\u307e\u3057\u305f\uff08\u88683\uff09\u3002\u6cbb\u7642\u524d\u306e\u521d\u8a3a\u60a3\u8005\u304b\u3089\u691c\u51fa\u3055\u308c\u305fA(H1N1)pdm09\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b921\u4ef6\u306b\u306f\u3001PA\u907a\u4f1d\u5b50\u306e\u85ac\u5264\u8010\u6027\u5909\u7570\u306f\u691c\u51fa\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff080\/21\uff09\u3002\u4e00\u65b9\u3001A(H3N2)\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9254\u4ef6\u4e2d2\u4ef6\u3067PA\/I38T\u5909\u7570\u304c\u521d\u8a3a\u6642\u306e\u60a3\u8005\u304b\u3089\u78ba\u8a8d\u3055\u308c\u3001\u983b\u5ea6\u306f0.8\uff05\uff082\/254\uff09\u3067\u3057\u305f\u3002\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u6295\u85ac\u524d\u3068\u6295\u85ac\u5f8c\u306e2\u56de\u691c\u4f53\u304c\u63a1\u53d6\u3055\u308c\u305fA(H1N1)pdm09\u967d\u6027\u60a3\u80051\u4f8b\u306e\u6295\u85ac\u5f8c\u306b\u63a1\u53d6\u3055\u308c\u305f\u691c\u4f53\u306b\u306f\u3001PA\u907a\u4f1d\u5b50\u306e\u85ac\u5264\u8010\u6027\u5909\u7570\u306f\u691c\u51fa\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u6cbb\u7642\u3092\u3046\u3051\u305fA(H3N2)\u967d\u6027\u60a3\u800551\u4f8b\u306e\u3046\u3061\u6295\u85ac\u5f8c\u306e\u691c\u4f537\u4ef6\u306bPA\u907a\u4f1d\u5b50\u306e\u85ac\u5264\u8010\u6027\u5909\u7570\u304c\u78ba\u8a8d\u3055\u308c\u3001\u983b\u5ea6\u306f13.7\uff05\uff087\/51\uff09\u3067\u3057\u305f\u3002\u307e\u305f\u3001\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u6295\u85ac\u5f8c\u306e\u691c\u4f53\u3067\u30b5\u30f3\u30ac\u30fc\u6cd5\u306b\u3088\u308a\u89e3\u6790\u3067\u304d\u305f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6A(H3N2)\u30a6\u30a4\u30eb\u30b929\u4ef6\u3092\u5206\u6bcd\u306b\u3059\u308b\u3068\u3001\u983b\u5ea6\u306f24.1\uff05\uff087\/29\uff09\u306b\u4e0a\u6607\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/05.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6253\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/05-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/05-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/05-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/05.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u306e\u611f\u53d7\u6027\u306b\u5f71\u97ff\u3059\u308bNA\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306fNGS\u3067\u89e3\u6790\u3057\u307e\u3057\u305f\u3002\u6cbb\u7642\u524d\u521d\u8a3a\u6642\u306b\u63a1\u53d6\u3055\u308c\u305f7\u4f8b\u306e\u691c\u4f53\u304b\u3089\u691c\u51fa\u3055\u308c\u305fA(H1N1)pdm09\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u3001\u53ca\u3073161\u4f8b\u306eA(H3N2) \u30a6\u30a4\u30eb\u30b9\u306b\u306f\u3001NA\u907a\u4f1d\u5b50\u306b\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u306b\u5bfe\u3059\u308b\u85ac\u5264\u8010\u6027\u5909\u7570\u306f\u898b\u3064\u304b\u308a\u307e\u305b\u3093\u3067\u3057\u305f\uff08\u88684\uff09\u3002\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u6295\u85ac\u524d\u3068\u6295\u85ac\u5f8c\u306e2\u56de\u691c\u4f53\u304c\u63a1\u53d6\u3055\u308c\u305fA(H3N2)\u967d\u6027\u60a3\u800523\u4f8b\u306b\u3064\u3044\u3066\u306f\u3001\u6295\u85ac\u5f8c\u306e\u518d\u8a3a\u6642\u306e\u691c\u4f53\u304b\u3089\u30aa\u30bb\u30eb\u30bf\u30df\u30d3\u30eb\u8010\u6027\u5909\u7570\u306f\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\uff080\/23\uff09\u3002\u540c\u69d8\u306b\u3001\u6295\u85ac\u5f8c\u518d\u8a3a\u6642\u306b\u63a1\u53d6\u3055\u308cNGS\u306b\u3088\u308b\u89e3\u6790\u304c\u53ef\u80fd\u3067\u3042\u3063\u305f2\u4ef6\u306eA(H3N2)\u3092\u5206\u6bcd\u3068\u3057\u305f\u5834\u5408\u306b\u3082\u3001NA\u907a\u4f1d\u5b50\u306e\u85ac\u5264\u8010\u6027\u5909\u7570\u306f\u306a\u304b\u3063\u305f\u305f\u3081\u983b\u5ea6\u306f0.0%\u3067\u3057\u305f\uff080\/2\uff09\uff08\u88684\uff09\u3002<\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/06.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6254\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/06-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/06-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/06-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/06.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>A\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306b\u3064\u3044\u3066\u3001HA\u907a\u4f1d\u5b50\u306e\u7cfb\u7d71\u6a39\u89e3\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u30022022-23\u5e74\u30b7\u30fc\u30ba\u30f3\u306b\u65e5\u672c\u3067\u6d41\u884c\u3057\u305fA(H3N2)\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306f\u8907\u6570\u306e\u907a\u4f1d\u7684\u30af\u30ec\u30fc\u30c9\u306b\u5206\u304b\u308c\u3066\u304a\u308a\u3001\u51ac\u5b63\u306b\u6d41\u884c\u3057\u305f\u30a6\u30a4\u30eb\u30b9\u306f\u3001\u307b\u3068\u3093\u3069\u30af\u30ec\u30fc\u30c92a.3a\u306b\u5c5e\u3057\u3001\u6625\u304b\u3089\u590f\u306b\u304b\u3051\u3066\u6d41\u884c\u3057\u305f\u30a6\u30a4\u30eb\u30b9\u306f\u30af\u30ec\u30fc\u30c92b\u306b\u5c5e\u3057\u307e\u3057\u305f\uff08\u56f33-1\uff09\u3002\u521d\u8a3a\u6642\u306e\u691c\u4f53\u304b\u3089\u691c\u51fa\u3055\u308c\u305f2\u4ef6\u306ePA\/I38\u5909\u7570\u682a\u306f\u3001\u305d\u308c\u305e\u308c2a.1\u3068\u30012b\u3068\u3044\u3046\u5225\u306eHA\u30af\u30ec\u30fc\u30c9\u306b\u5c5e\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u308c\u306fPA\u5909\u7570\u682a\u304c1\u3064\u306e\u7cfb\u7d71\u304b\u3089\u30af\u30ed\u30fc\u30ca\u30eb\u306a\u611f\u67d3\u4f1d\u64ad\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u72b6\u614b\u3067\u306f\u7121\u3044\u3053\u3068\u3092\u793a\u3057\u3066\u307e\u3059\u3002\u4e00\u65b9\u30017\u6708\u521d\u65ec\u306b\u6c96\u7e04\u3067\u63a1\u53d6\u3055\u308c\u305fA(H1N1)pdm09\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306f5a.2a\u306b\u5c5e\u3057\u3001\u4e2d\u6771\u3001\u6771\u4eac\u3001\u6b27\u5dde\u306e\u682a\u3068\u907a\u4f1d\u7684\u306b\u985e\u4f3c\u3057\u3066\u3044\u307e\u3057\u305f\u3002\u30df\u30e3\u30f3\u30de\u30fc\u304b\u30897\u6708\u306b\u65e5\u672c\u306b\u8f38\u5165\u3055\u308c\u305f\u3068\u8003\u3048\u3089\u308c\u308bA(H1N1)pdm09\u30a6\u30a4\u30eb\u30b9\u306f\u30015a.2a\u306b\u5c5e\u3057\u3066\u304a\u308a\u3001\u4e2d\u56fd\u3084\u30bf\u30a4\u3067\u691c\u51fa\u3055\u308c\u305f\u682a\u306b\u8fd1\u4f3c\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f33-2\uff09\u3002<\/p>\n<p><a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/08.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-6255\" src=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/08-600x450.png\" alt=\"\" width=\"600\" height=\"450\" srcset=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/08-600x450.png 600w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/08-768x576.png 768w, http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/08.png 960w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-size: 14pt;\"><strong>Summary results of influenza virus detection and variant strains that confer reduced susceptibility to antivirals in Japan in 2022-2023 season. Updated on 2024.10.17.<\/strong><\/span><\/p>\n<p>From October 2022 to September 2023, we monitored influenza virus circulation and variant strains that confer reduced susceptibility to Baloxavir or Oseltamivir in Japan.<\/p>\n<p>Eight outpatient clinics from seven prefectures nationwide participated in the study (Figure 1). Upper respiratory swabs were collected from influenza-like illness (ILI) patients who visited any of the collaborative clinics and tested positive by rapid diagnostic test kit (RDT). After transportation to Niigata University, all clinical samples were examined by RT-PCR for typing\/subtyping of influenza virus. Among 297 received clinical samples, 248 (83.5%) were identified as A(H3N2), 25 (8.4%) as A(H1N1)pdm09, 10 (3.4%) as unsubtyped influenza A, and 14 were negative for influenza virus by RT-PCR (Table 1). Influenza A(H3N2) predominantly circulated throughout Japan, although a few A(H1N1)pdm09 viruses were detected in Niigata, Tokyo, Yamaguchi, and Okinawa (Figure 1, Table 1).<\/p>\n<p>&nbsp;<\/p>\n<p>Influenza activity started in late 2022 and peaked in January (Figure 2). A secondary small peak was detected in March 2023, which gradually decreased. Influenza circulation continued at a low level from March to September 2023 (Figure 2). Influenza A(H3N2) predominantly circulated throughout the studied areas, but\u00a0 A(H1N1)pdm09 viruses were also detected in Niigata, Tokyo, Yamaguchi, and Okinawa (Figures 1 and 2).<\/p>\n<p>&nbsp;<\/p>\n<p>Amino acid substitutions in the influenza virus genome as drug-resistant markers, PA\/I38T in the PA gene for Baloxavir and NA\/H275Y in the NA gene for Oseltamivir, were determined by RT-PCR. Subsequently PA or NA variants in relevant genes, which affect Baloxavir or Oseltamivir sensitivity were confirmed by next-generation sequencing (NGS) and the Sanger method. A first sample was collected at the initial visit (pre-treatment), and a second sample was collected at a follow-up visit 3-7 days after treatment with baloxavir or oseltamivir.<\/p>\n<p>&nbsp;<\/p>\n<p>By RT-PCR, the substitution with reduced susceptibility to Baloxavir (PA\/I38T) was observed in two out of 248 A(H3N2) viruses before treatment, representing a frequency of 0.8% (2\/248) (Table 2). Using NGS to verify PA gene substitutions, we detected the PA\/I38T mutation in 2 cases, consistent with RT-PCR results. However, no other PA variants were detected (0.8%, 2\/248). On the contrary, no PA variants were detected in the 25 pre-treatment influenza A(H1N1)pdm09 samples using both RT-PCR and NGS methods (Table 2).<\/p>\n<p>&nbsp;<\/p>\n<p>Among A(H3N2) patients treated with Baloxavir (n=54), six cases with PA\/I38T substitution were detected from clinical samples at the second visit by RT-PCR, defining the frequency of 11.1% for PA\/I38T based on the number of Baloxavir-treated patients (6\/54) (Table 2). If the denominator is based on 21 cases positive by RT-PCR at the second visit, the frequency rose to 28.6% (6\/21). We conducted NGS analysis on paired samples from the 54 A(H3N2) patients. Eight cases with PA substitutions were found after baloxavir treatment, representing a frequency of 14.8% (8\/54). Of these eight cases, four were PA\/I38T, one was PA\/I38M, and one each of mixed substitutions PA\/I38M\/T, PA\/E23K+I38T, and PA\/E23G+I38T. When we use the denominator based on 21 cases positive by RT-PCR and eligible for NGS at the second visit after Baloxavir treatment, the frequency became 38.1% (8\/21) (Table 2). No PA variants (0\/1) were detected by both RT-PCR and NGS after treatment with Baloxavir in one patient with influenza A(H1N1)pdm09 (Table 2).<\/p>\n<p>&nbsp;<\/p>\n<p>Using Sanger method sequencing, 275 pre-treatment viruses were analyzed (Table 3). Among influenza A(H1N1)pdm09 strains sequenced before treatment (n=21), no PA substitutions were found (0\/21). Out of 254 pre-treated influenza A(H3N2) viruses sequenced, two were found to harbor the PA\/I38T substitution, with a frequency of 0.8% (2\/254). In A(H1N1)pdm09, no PA variant was detected in one patient who had the second sampling after Baloxavir treatment (0\/1) (Table 3). Among 51 A(H3N2) who had the second sampling after Baloxavir treatment, seven possessed PA variants, representing a frequency of 13.7% (7\/51). Based on 29 cases eligible to be sequenced by the Sanger method at the second visit, the frequency rose to 24.1% (7\/29).<\/p>\n<p>&nbsp;<\/p>\n<p>We analyzed NA gene by NGS to find NA variants that affect sensitivity to Oseltamivir. NGS results showed no substitution in the NA gene affecting sensitivity to Oseltamivir in seven A(H1N1)pdm09 cases and 161 A(H3N2) cases before treatment (Table 4). Among 23 Oseltamivir-treated cases sampled twice at the first and second visits, no NA variants were detected by NGS analysis in the second visit samples (0\/23). If we base the denominator on the two samples successfully analyzed by NGS at the second visit after Oseltamivir treatment, the frequency remained 0.0% (0\/2) (Table 4).<\/p>\n<p>&nbsp;<\/p>\n<p>We performed a phylogenetic analysis of the HA gene of influenza A viruses. Influenza A(H3N2) viruses circulated in Japan had several genetic clades; however, most collected viruses split into two clades (2a.3a and 2b). The clade 2a.3a consists mainly of viruses circulated in winter, and the 2b clade was formed from spring-summer strains (Figure 3-1). Two viruses harboring the PA\/I38T substitution collected at the pre-treatment visit, marked with blue arrows, belonged to different HA clades: one to 2a.1 and the other to 2b (Figure 3-1). This indicates no evidence for a clonal spread of the primary PA variants in the community. Influenza A(H1N1)pdm09, collected in early July in Okinawa, belonged to clade 5a.2a and had close genetic similarity with strains from the Middle East, Tokyo, and Europe (Figure 3-2). However, one A(H1N1)pdm09 virus, suspected to be imported from Myanmar to Japan in July, belonged to clade 5a.2a and had genetic proximity to strains from China and Thailand.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2022-2023\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6d41\u884c\u682a\u3068\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u85ac\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u6982\u8981\uff082024\u5e7410\u670817\u65e5\u66f4\u65b0\uff09 2022\u5e7410\u6708\u304b\u30892023\u5e749\u6708\u307e\u3067\u306e\u671f\u9593\u4e2d\u3001\u65e5\u672c\u5404\u5730\u3067\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306e\u6d41\u884c\u52d5\u5411\u3068<a href=\"http:\/\/www.med.niigata-u.ac.jp\/pub\/2024\/10\/17\/2022-2023%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%b5%e3%83%bc-2\/\"> &#8230;\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":6249,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1,3,11],"tags":[],"class_list":["post-6246","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","category-blog","category-influenzasearch"],"jetpack_featured_media_url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2024\/10\/01.png","jetpack_shortlink":"https:\/\/wp.me\/ph72WZ-1CK","jetpack-related-posts":[{"id":6461,"url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2025\/12\/25\/2025%e5%b9%b412%e6%9c%884%e6%97%a5%e3%80%80%e6%8a%97%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e5%89%a4%e6%84%9f%e5%8f%97%e6%80%a7%e4%bd%8e%e4%b8%8b%e6%a0%aa%e8%aa%bf%e6%9f%bb\/","url_meta":{"origin":6246,"position":0},"title":"2025\u5e7412\u67084\u65e5\u3000\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u5264\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u7d50\u679c","author":"public-health","date":"2025\u5e7412\u670825\u65e5","format":false,"excerpt":"2025-2026\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6d41\u884c\u682a\u3068\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u85ac\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u2026","rel":"","context":"What\u2019s New","block_context":{"text":"What\u2019s New","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/12\/%E5%B9%BB%E7%81%AF%E7%89%871.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/12\/%E5%B9%BB%E7%81%AF%E7%89%871.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/12\/%E5%B9%BB%E7%81%AF%E7%89%871.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/12\/%E5%B9%BB%E7%81%AF%E7%89%871.jpg?resize=700%2C400 2x"},"classes":[]},{"id":6294,"url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2025\/01\/23\/2024-2025%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e6%b5%81%e8%a1%8c\/","url_meta":{"origin":6246,"position":1},"title":"2025\u5e741\u670817\u65e5\u3000\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u5264\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u7d50\u679c","author":"public-health","date":"2025\u5e741\u670823\u65e5","format":false,"excerpt":"2024-2025\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6d41\u884c\u682a\u3068\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u85ac\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u2026","rel":"","context":"What\u2019s New","block_context":{"text":"What\u2019s New","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%891.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%891.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%891.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%891.jpg?resize=700%2C400 2x"},"classes":[]},{"id":6270,"url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2025\/01\/06\/2023-2024%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e6%b5%81%e8%a1%8c\/","url_meta":{"origin":6246,"position":2},"title":"2023-2024\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\u306e\u6982\u8981\uff082024\u5e7412\u670825\u65e5\u4f5c\u6210\uff09","author":"public-health","date":"2025\u5e741\u67086\u65e5","format":false,"excerpt":"2023-2024\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6d41\u884c\u682a\u3068\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u85ac\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u2026","rel":"","context":"What\u2019s New","block_context":{"text":"What\u2019s New","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/Figure-2.png?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/Figure-2.png?resize=350%2C200 1x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/Figure-2.png?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/Figure-2.png?resize=700%2C400 2x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/01\/Figure-2.png?resize=1050%2C600 3x"},"classes":[]},{"id":6010,"url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2023\/10\/13\/2022-2023%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%b5%e3%83%bc\/","url_meta":{"origin":6246,"position":3},"title":"2022-2023\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\u306e\u6982\u8981","author":"public-health","date":"2023\u5e7410\u670813\u65e5","format":false,"excerpt":"2022-2023\u5e74\u306e\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30b7\u30fc\u30ba\u30f3\u4e2d\u3001\u6211\u3005\u306f\u521d\u8a3a\u6642260\u691c\u4f53\u3092\u53ce\u96c6\u3057\u30012\u56de\u76ee\u306e\u518d\u8a3a\u691c\u4f53\u306f8\u2026","rel":"","context":"What\u2019s New","block_context":{"text":"What\u2019s New","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/10\/2023-flu-report-%E3%81%BE%E3%81%A8%E3%82%81%E6%97%A5%E6%9C%AC%E8%AA%9E-for-HP2_Page_1.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/10\/2023-flu-report-%E3%81%BE%E3%81%A8%E3%82%81%E6%97%A5%E6%9C%AC%E8%AA%9E-for-HP2_Page_1.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/10\/2023-flu-report-%E3%81%BE%E3%81%A8%E3%82%81%E6%97%A5%E6%9C%AC%E8%AA%9E-for-HP2_Page_1.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/10\/2023-flu-report-%E3%81%BE%E3%81%A8%E3%82%81%E6%97%A5%E6%9C%AC%E8%AA%9E-for-HP2_Page_1.jpg?resize=700%2C400 2x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/10\/2023-flu-report-%E3%81%BE%E3%81%A8%E3%82%81%E6%97%A5%E6%9C%AC%E8%AA%9E-for-HP2_Page_1.jpg?resize=1050%2C600 3x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/10\/2023-flu-report-%E3%81%BE%E3%81%A8%E3%82%81%E6%97%A5%E6%9C%AC%E8%AA%9E-for-HP2_Page_1.jpg?resize=1400%2C800 4x"},"classes":[]},{"id":6322,"url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2025\/03\/07\/2023-2024%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e3%82%b5%e3%83%bc\/","url_meta":{"origin":6246,"position":4},"title":"2023-2024\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\u306e\u6982\u8981\uff082025\u5e742\u670827\u65e5\u66f4\u65b0\uff09","author":"public-health","date":"2025\u5e743\u67087\u65e5","format":false,"excerpt":"2023-2024\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u6d41\u884c\u682a\u3068\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u85ac\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u2026","rel":"","context":"What\u2019s New","block_context":{"text":"What\u2019s New","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/03\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/03\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/03\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/03\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=700%2C400 2x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2025\/03\/%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=1050%2C600 3x"},"classes":[]},{"id":5843,"url":"http:\/\/www.med.niigata-u.ac.jp\/pub\/2023\/02\/15\/%e6%9c%ac%e9%82%a6%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b2021-2022%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%8a%97%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8%e3%83%b3%e3%82%b6%e5%89%a4\/","url_meta":{"origin":6246,"position":5},"title":"\u672c\u90a6\u306b\u304a\u3051\u308b2021\/2022\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u5264\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u7d50\u679c","author":"public-health","date":"2023\u5e742\u670815\u65e5","format":false,"excerpt":"2021\/22\u5e74\u30b7\u30fc\u30ba\u30f3\u3000\u6297\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u5264\u611f\u53d7\u6027\u4f4e\u4e0b\u682a\u8abf\u67fb\u306e\u7d50\u679c \u65b0\u6f5f\u5927\u5b66\u5927\u5b66\u9662\u533b\u6b6f\u5b66\u7dcf\u5408\u7814\u7a76\u79d1\u30fb\u2026","rel":"","context":"What\u2019s New","block_context":{"text":"What\u2019s New","link":"http:\/\/www.med.niigata-u.ac.jp\/pub\/category\/news\/"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/02\/21-22_%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/02\/21-22_%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=350%2C200 1x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/02\/21-22_%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=525%2C300 1.5x, https:\/\/i0.wp.com\/www.med.niigata-u.ac.jp\/pub\/wppublichealth\/wp-content\/uploads\/2023\/02\/21-22_%E3%82%B9%E3%83%A9%E3%82%A4%E3%83%892.jpg?resize=700%2C400 2x"},"classes":[]}],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/6246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/comments?post=6246"}],"version-history":[{"count":1,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/6246\/revisions"}],"predecessor-version":[{"id":6262,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/posts\/6246\/revisions\/6262"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/media\/6249"}],"wp:attachment":[{"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/media?parent=6246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/categories?post=6246"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/www.med.niigata-u.ac.jp\/pub\/wp-json\/wp\/v2\/tags?post=6246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}