{"id":6611,"date":"2026-04-10T16:33:25","date_gmt":"2026-04-10T07:33:25","guid":{"rendered":"https:\/\/www.med.niigata-u.ac.jp\/pub\/?p=6611"},"modified":"2026-04-10T16:36:34","modified_gmt":"2026-04-10T07:36:34","slug":"2023-2024%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e5%ad%a3%e7%af%80%e6%80%a7%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8","status":"publish","type":"post","link":"https:\/\/www.med.niigata-u.ac.jp\/pub\/2026\/04\/10\/2023-2024%e5%b9%b4%e3%82%b7%e3%83%bc%e3%82%ba%e3%83%b3%e3%81%ae%e6%97%a5%e6%9c%ac%e3%81%ab%e3%81%8a%e3%81%91%e3%82%8b%e5%ad%a3%e7%af%80%e6%80%a7%e3%82%a4%e3%83%b3%e3%83%95%e3%83%ab%e3%82%a8\/","title":{"rendered":"2023\u20132024\u5e74\u30b7\u30fc\u30ba\u30f3\u306e\u65e5\u672c\u306b\u304a\u3051\u308b\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\u306e\u907a\u4f1d\u7684\u591a\u69d8\u6027\u3068\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u8010\u6027\u5909\u7570\uff08PA\/I38T\uff09\u3092\u89e3\u6790"},"content":{"rendered":"

\u5f53\u6559\u5ba4\u306e\u674e\u5357\u541b\uff08Li Nanjun\uff09\u3055\u3093\u3092\u7b46\u982d\u8457\u8005\u3068\u3059\u308b\u8ad6\u6587
\n“Influenza PA Substitutions and Genetic Diversity of A(H1N1)pdm09, A(H3N2), and B\/Victoria Viruses in Japan During the 2023\u20132024 Season”
\n\u304c Viruses \u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002
\nhttps:\/\/doi.org\/10.3390\/v18010013<\/a><\/p>\n

\u672c\u7814\u7a76\u3067\u306f<\/strong>\u30012023\u5e7410\u6708\u304b\u30892024\u5e749\u6708\u306b\u304b\u3051\u3066\u3001\u65e5\u672c\u56fd\u51851\u90535\u770c\u30fb8\u30af\u30ea\u30cb\u30c3\u30af\u3067\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u69d8\u75c7\u72b6\u3092\u5448\u3057\u305f\u5916\u6765\u60a3\u8005210\u4f8b\u3092\u5bfe\u8c61\u306b\u3001\u5b63\u7bc0\u6027\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30a6\u30a4\u30eb\u30b9\uff08A(H1N1)pdm09\u30fbA(H3N2)\u30fbB\/Victoria\uff09\u306e\u907a\u4f1d\u7684\u7279\u5fb4\u3068\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u8010\u6027\u5909\u7570\uff08PA\/I38T\uff09\u3092\u89e3\u6790\u3057\u307e\u3057\u305f\u3002\u6b21\u4e16\u4ee3\u30b7\u30fc\u30b1\u30f3\u30b9\uff08NGS\uff09\u30fb\u30b5\u30f3\u30ac\u30fc\u6cd5\u30fb\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6RT-PCR\u306e3\u624b\u6cd5\u3092\u7d44\u307f\u5408\u308f\u305b\u3001\u30a6\u30a4\u30eb\u30b9\u306e\u30af\u30ec\u30fc\u30c9\u5206\u985e\u3001WHO\u30ef\u30af\u30c1\u30f3\u63a8\u5968\u682a\u3068\u306e\u9069\u5408\u6027\u8a55\u4fa1\u3001\u304a\u3088\u3073\u8010\u6027\u5909\u7570\u306e\u51fa\u73fe\u983b\u5ea6\u3092\u691c\u8a0e\u3057\u307e\u3057\u305f\u3002<\/p>\n

[\u56f31] \u30a6\u30a4\u30eb\u30b9\u4e9c\u578b\u306e\u5206\u5e03\u3068\u6d41\u884c\u63a8\u79fb<\/strong>\"\"<\/a>
\n\u6cbb\u7642\u524d\u306e\u6709\u52b9\u691c\u4f53181\u4f8b\u306e\u3046\u3061\u3001A(H1N1)pdm09\u304c44.2%\uff0880\u4f8b\uff09\u3001A(H3N2)\u304c37.6%\uff0868\u4f8b\uff09\u3001B\/Victoria\u304c18.2%\uff0833\u4f8b\uff09\u3092\u5360\u3081\u307e\u3057\u305f\u3002\u6d41\u884c\u306e\u65e9\u671f\uff082023\u5e7411\u6708\uff09\u306fA(H1N1)pdm09\u3068A(H3N2)\u306e\u6df7\u5408\u6d41\u884c\u3067\u3001\u305d\u306e\u5f8c2024\u5e741\u6708\u301c3\u6708\u306b\u304b\u3051\u3066B\/Victoria\u304c\u5897\u52a0\u3059\u308b\u3068\u3044\u3046\u5b63\u7bc0\u63a8\u79fb\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u6d41\u884c\u30d1\u30bf\u30fc\u30f3\u306f\u5168\u56fd\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\uff08NESID\uff09\u30c7\u30fc\u30bf\u3068\u3082\u4e00\u81f4\u3057\u3066\u3044\u307e\u3057\u305f\u3002<\/p>\n

A(H1N1)pdm09\uff1a\u30ef\u30af\u30c1\u30f3\u63a8\u5968\u682a\u3068\u8fd1\u7e01\u306aD.2\u7cfb\u7d71\u304c\u512a\u52e2<\/strong>
\n\"\"<\/a>
\n36\u4f8b\u306eNGS\u89e3\u6790\u3067\u306f\u3001\u3059\u3079\u3066\u306e\u682a\u304c\u30af\u30ec\u30fc\u30c95a.2a\u307e\u305f\u306f5a.2a.1\u306b\u5c5e\u3057\u3001\u305d\u306e\u3046\u306175%\uff0827\/36\u4f8b\uff09\u304cD.2\u30b5\u30d6\u30af\u30ec\u30fc\u30c9\u306b\u96c6\u7a4d\u3057\u307e\u3057\u305f\u3002D.2\u306f\u65e5\u672c\u30fb\u4e2d\u56fd\u30fb\u7c73\u56fd\u306e\u4e00\u90e8\u3067\u512a\u52e2\u306a\u7cfb\u7d71\u3067\u3042\u308a\u30012023\/24\u30b7\u30fc\u30ba\u30f3\u306e\u30ef\u30af\u30c1\u30f3\u682a\uff08A\/Victoria\/4897\/2022\uff09\u3068\u8fd1\u7e01\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002WHO\u306e\u6297\u539f\u6027\u89e3\u6790\u30c7\u30fc\u30bf\u3068\u3082\u6574\u5408\u3057\u3066\u304a\u308a\u3001H1N1pdm09\u6210\u5206\u306e\u30ef\u30af\u30c1\u30f3\u9069\u5408\u6027\u306f\u826f\u597d\u3068\u8a55\u4fa1\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

A(H3N2)\uff1a\u30ef\u30af\u30c1\u30f3\u682a\u3068\u4e56\u96e2\u3057\u305fJ\u7cfb\u7d71\uff082a.3a.1\uff09\u304c\u5168\u4f8b\u3092\u5360\u3081\u308b<\/strong>\"\"<\/a>
\n33\u4f8b\u306eNGS\u89e3\u6790\u3067\u306f\u3001\u3059\u3079\u3066\u306e\u682a\u304c2a.3a.1\uff08J\u7cfb\u7d71\uff09\u306b\u5206\u985e\u3055\u308c\u3001\u305d\u306e\u3046\u3061J.1\u304c87.8%\uff0829\/33\u4f8b\uff09\u3092\u5360\u3081\u307e\u3057\u305f\u3002J\u7cfb\u7d71\u306f2023\/24\u30b7\u30fc\u30ba\u30f3\u306e\u30ef\u30af\u30c1\u30f3\u63a8\u5968\u682aA\/Darwin\/9\/2021\uff08Darwin\u7cfb\u7d71\uff09\u3068\u7cfb\u7d71\u7684\u306b\u4e56\u96e2\u3057\u3066\u304a\u308a\u3001\u6297\u539f\u6027\u306e\u5dee\u7570\u3082\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u77e5\u898b\u306f2024\/25\u30b7\u30fc\u30ba\u30f3\u306b\u304a\u3044\u3066J\u7cfb\u7d71\u3092\u4ee3\u8868\u3059\u308bA\/California\/122\/2022\u3078\u306e\u30ef\u30af\u30c1\u30f3\u682a\u66f4\u65b0\u3092\u652f\u6301\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u3002\u65e5\u672c\u3067\u691c\u51fa\u3055\u308c\u305f\u682a\u306f\u3001\u6b27\u5dde\u30fb\u5317\u7c73\u30fb\u6771\u30a2\u30b8\u30a2\u30fb\u6771\u5357\u30a2\u30b8\u30a2\u306e\u540c\u6642\u671f\u306e\u682a\u3068\u3082\u6df7\u5728\u3057\u3066\u304a\u308a\u3001J\u7cfb\u7d71\u304c\u30b0\u30ed\u30fc\u30d0\u30eb\u306b\u5faa\u74b0\u3057\u3066\u3044\u305f\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

B\/Victoria\uff1aV1A.3a.2\uff08C.5\u7cfb\u7d71\uff09\u304c\u4e16\u754c\u7684\u306a\u52d5\u5411\u3068\u4e00\u81f4<\/strong>
\n\"\"<\/a>
\n26\u4f8b\u306eNGS\u89e3\u6790\u3067\u306f\u3001\u3059\u3079\u3066\u306e\u682a\u304cV1A.3a.2\u306eC.5\u30d0\u30c3\u30af\u30dc\u30fc\u30f3\u4e0a\u306b\u4f4d\u7f6e\u3057\u3001C.5.1\uff0854%\uff09\u3068C.5.7\uff0846%\uff09\u306e2\u3064\u306e\u30b5\u30d6\u30af\u30ec\u30fc\u30c9\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u5206\u5e03\u306f\u4e16\u754c\u7684\u306a\u52d5\u5411\uff08C.5.1\u304c\u7c73\u56fd\u30fb\u6b27\u5dde\u306e\u4e00\u90e8\u3001C.5.7\u304c\u6771\u30a2\u30b8\u30a2\u30fb\u30aa\u30fc\u30b9\u30c8\u30e9\u30ea\u30a2\u30fb\u30e6\u30fc\u30e9\u30b7\u30a2\u3067\u512a\u52e2\uff09\u3068\u4e00\u81f4\u3057\u3066\u304a\u308a\u3001\u65e5\u672c\u306e\u6d41\u884c\u3082\u56fd\u969b\u7684\u306a\u5faa\u74b0\u306e\u4e00\u90e8\u3092\u69cb\u6210\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u30022023\/24\u30b7\u30fc\u30ba\u30f3\u306e\u30ef\u30af\u30c1\u30f3\u682a\uff08B\/Austria\/1359417\/2021\uff09\u306fV1A.3a.2\u306b\u5c5e\u3057\u3066\u304a\u308a\u3001\u6297\u539f\u6027\u306e\u5dee\u7570\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n

\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u8010\u6027\u5909\u7570\uff08PA\/I38T\uff09\u306e\u691c\u51fa\u72b6\u6cc1<\/strong>\"\"<\/a>
\n\u6cbb\u7642\u524d\u691c\u4f53181\u4f8b\u3059\u3079\u3066\u306b\u304a\u3044\u3066PA\/I38T\u5909\u7570\u306f\u691c\u51fa\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3053\u306e\u7d50\u679c\u306f\u3001\u56fd\u7acb\u611f\u67d3\u75c7\u7814\u7a76\u6240\u306b\u3088\u308b\u5168\u56fd\u30b5\u30fc\u30d9\u30a4\u30e9\u30f3\u30b9\uff08A(H1N1)pdm09 0.4%\u3001A(H3N2) 0.5%\u3001B\/Victoria 0%\uff09\u3084WHO\u306e\u96c6\u8a08\uff08\u22640.12%\uff09\u3068\u3082\u6574\u5408\u3057\u3066\u3044\u307e\u3057\u305f\u3002
\n\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u6cbb\u7642\u5f8c\u691c\u4f53\u3067\u306f\u3001A(H3N2)\u306e1\u4f8b\uff087.1%\uff09\u306b\u304a\u3044\u3066PA\/I38T\u5909\u7570\u304c\u691c\u51fa\u3055\u308c\u3001RT-PCR\u30fb\u30b5\u30f3\u30ac\u30fc\u30fbNGS\u306e3\u624b\u6cd5\u3059\u3079\u3066\u3067\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001B\/Victoria \u306e1\u4f8b\u306b\u304a\u3044\u3066\u3082NGS\u306e\u307f\u3067PA\/I38T\u5909\u7570\uff08\u5909\u7570\u983b\u5ea625.0%\uff09\u304c\u691c\u51fa\u3055\u308c\u307e\u3057\u305f\u3002B\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u304a\u3051\u308bPA\/I38T\u5909\u7570\u306e\u81e8\u5e8a\u7684\u691c\u51fa\u306f\u3053\u308c\u307e\u3067\u5831\u544a\u304c\u306a\u304f\u3001\u672c\u7814\u7a76\u304c\u521d\u5831\u544a\u306b\u76f8\u5f53\u3057\u307e\u3059<\/strong>\u3002<\/p>\n

B\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6PA\/I38T\u691c\u51fa\u4f8b\uff1a\u5bb6\u65cf\u5185\u66dd\u9732\u3092\u4f34\u304613\u6b73\u60a3\u8005\u306e\u7d4c\u904e<\/strong>
\nB\/Victoria\u967d\u6027\u3067\u8010\u6027\u5909\u7570\u304c\u691c\u51fa\u3055\u308c\u305f\u60a3\u80052\uff0813.3\u6b73\uff09\u306f\u3001\u5bb6\u65cf\u5185\u3067B\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u7f79\u60a3\u3057\u305f\u5144\u5f1f2\u4eba\uff086\u6b73\u30fb10\u6b73\uff09\u306e\u5f8c\u306b\u767a\u75c7\u3057\u307e\u3057\u305f\u3002\u521d\u56de\u53d7\u8a3a\u6642\u306f\u8fc5\u901f\u6297\u539f\u691c\u67fb\u9670\u6027\u3067\u3042\u3063\u305f\u305f\u3081\u691c\u4f53\u63a1\u53d6\u306f\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u30d0\u30ed\u30ad\u30b5\u30d3\u30eb\u304c\u81e8\u5e8a\u7684\u5224\u65ad\u3067\u6295\u4e0e\u3055\u308c\u307e\u3057\u305f\u3002\u7d041\u9031\u9593\u5f8c\u306b\u518d\u3073\u767a\u71b1\u30fb\u75c7\u72b6\u304c\u51fa\u73fe\u3057\u3001\u518d\u53d7\u8a3a\u6642\u306e\u691c\u4f53\u306b\u3066B\u578b\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u967d\u6027\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u306e\u691c\u4f53\u306f\u30a6\u30a4\u30eb\u30b9\u91cf\u304c\u4f4e\u304fRT-PCR\u304a\u3088\u3073\u30b5\u30f3\u30ac\u30fc\u6cd5\u3067\u306f\u8010\u6027\u5909\u7570\u3092\u691c\u51fa\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001NGS\u306b\u3088\u3063\u3066PA\/I38T\u5909\u7570\u304c\u691c\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u672c\u75c7\u4f8b\u306f\u3001\u30a6\u30a4\u30eb\u30b9\u91cf\u304c\u4f4e\u3044\u691c\u4f53\u306b\u304a\u3051\u308b\u8010\u6027\u5909\u7570\u306e\u691c\u51fa\u306bNGS\uff08\u6b21\u4e16\u4ee3\u30b7\u30fc\u30af\u30a8\u30f3\u30b9\uff09\u304c\u6709\u52b9\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3059\u91cd\u8981\u306a\u77e5\u898b\u3067\u3059\u3002<\/p>\n

\u672c\u7814\u7a76\u306e\u610f\u7fa9<\/strong>
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\u8ad6\u6587\u60c5\u5831
\nLee N, Tang JW, Chon I, et al.
\nInfluenza PA Substitutions and Genetic Diversity of A(H1N1)pdm09, A(H3N2), and B\/Victoria Viruses in Japan During the 2023\u20132024 Season.
\nViruses. 2026;18(1):13.
\nDOI: https:\/\/doi.org\/10.3390\/v18010013<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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