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国内特許
| 1. | 特願2024-199014, 発明者:芝田 晋介, 川田治良, 新山瑛理, 寺西知子, 谷口司, 井樋田悟史, 共同出願人:新潟大学, 株式会社Jikisak Bioengineering, シャープ株式会社, 発明の名称:インビトロ疼痛モデル及びそれを用いる疼痛測定方法, 出願日 令和6年11月14日 |
| 2. | 特願2020-181354, 発明者:芝田 晋介 (1/6), 川田治良, 特許出願人:学校法人慶應義塾, 株式会社Jiksak Bioengineering, 発明の名称:人工軸索束, 整理番号: KP-17895, 提出日:令和2年10月29日 |
| 3. | 特願2018-248067, 発明者:芝田 晋介 (1/4), 後藤修一, 特許出願人: 学校法人慶應義塾, サンユー電子株式会社, 発明の名称: 電子顕微鏡用試料の作成システム、電子顕微鏡用試料の作成方法およびこれに用いられるプラズマ処理装置、スパッタ装置、テープ搬送機構, 整理番号: S180001, 提出日: 平成30年12月28日, 国際特許分類: G01N 1/28 |
国際特許
| 4. | 国際特許出願番号: PCT/JP2021/039869, 発明者:芝田 晋介, 木村洋朗, 西島貴之, 信藤知子, 岡野栄之, 川田治良, 特許出願人: 学校法人慶應義塾, 株式会社Jiksak Bioengineering, 発明の名称: 人工軸索束, 提出日: 2021年10月28日, 整理番号: FP4719PCT/P10000003447 |
| 5. | 国際特許出願番号: PCT/JP2019/051141, 発明者:芝田 晋介 (1/4), 後藤 修一, 権利者: 学校法人慶應義塾, サンユー電子株式会社, 発明の名称: 電子顕微鏡用試料の作成システム、電子顕微鏡用試料の作成方法およびこれに用いられるプラズマ処理装置、スパッタ装置、テープ搬送機構, 提出日: 2019年12月26日, 整理番号: P10000003070 |
原著論文
2026年
| 1. | 1. Okuyama K, Komaki Y, Ishihara M, Kurosaki Y, Tsuchiya S, Hayatsu M, Nakayama J, Uchiyama K, Itoh K, Nagai T, Shindo T, Moritoki N, Kawashima H, Shibata S*. “Advances in multiscale myelin imaging: from classical histology to functional insights” Front. Cell. Neurosci. 2026 Feb 18;20:1771168. doi: 10.3389/fncel.2026.1771168. eCollection 2026. PMID: 41788197 (*corresponding author) |
| 2. | 2. Nishikubo K, Hitomi K, Sugihara R, Higuchi K, Quan L, Uyeda A, Nameta M, Okuyama K, Shibata S, Kato Y, Muramatsu R. “Integrated respiratory functions predict myelin status in the mouse brain” NPJ Biomed Innov. 2026 in press |
| 3. | 3. Amemiya T, Ouchi T, Kimura H, Okuyama K, Phan TQ, Iwamoto T, Nakagawa T, Matsumoto M, Nakamura M, Okano H, Nagoshi N*, Shibata S*. “Enhanced nerve regeneration after transplantation of NCAM-positive neural crest-like cells derived from human iPSC.” Inflamm Regen. 2026 Feb 11. doi: 10.1186/s41232-026-00409-5. PMID: 41673753 (*corresponding author) |
| 4. | 4. Takahashi K, Kato C, Ueda K, Nakamura S, Ozawa F, Moritoki N, Shibata S, Takahashi S, Morimoto S, Okano H. “Diagnostic potential of cryptic exon-derived peptides in serum extracellular vesicles for sporadic amyotrophic lateral sclerosis.” Inflamm Regen. 2026 Jan 29. doi: 10.1186/s41232-026-00404-w. PMID: 41612503 |
2025年
| 5. | 5. Yamamoto K, Kodo K, Shirai M, Shibata S, Tsuchihashi T, Uchida T, Uchida K, Yamagishi H. “Maternal Folic Acid Supplementation Ameliorates Outflow Tract Malformations in Tbx1 Hypomorphic Mice via Notch and Midkine Signaling” Circ J. 2025 Dec 26. doi: 10.1253/circj.CJ-25-0958. PMID: 41485949 |
| 6. | Mikami Y, Kuroda E, Kimura S, Hayatsu M, Watanabe K, Tsuda H, Nakamura Y, Sagawa T, Ichinose T, Takano H, Toriumi T. “Bronchus-associated lymphoid tissue: a review of its development and function, including recent findings on the impact of environmental particulate exposure.” Clin Exp Med. 2025 Nov 18;26(1):2. doi: 10.1007/s10238-025-01918-2. |
| 7. | 6. Ise M, Bizen N, Simankova A, Okuyama K, Shibata S, Tada M, Takebayashi H. “An inducible oligodendrocyte dysfunction triggered a pathological cascade of massive microglial activation and neurodegeneration.” Neurobiol Dis. 2025 Oct 16;216:107142. doi: 10.1016/j.nbd.2025.107142. PMID: 41109356 |
| 8. | Sáez-Chandía J, Castillo-Quispe S, Okamoto K, Kurahashi A, Kodaira K, Aihara K, Suzuki-Barrera K, Kaku M, Mikami Y, Terunuma M, Yamamura K, Hayashi T, Saeki M, Kakihara Y. “Effects of Freeze-Dried Sake Lees and Rice Koji Extract on Osteoporosis in a Postmenopausal Mouse Model.” Nutrients. 2025 Sep 27;17(19):3077. doi: 10.3390/nu17193077. |
| 9. | Mikami Y, Hayatsu M, Kuroda E, Tsuda H, Toriumi T, Mizutani Y, Ichinose T, Honda A, Takano H. “Characterization of bronchus-associated lymphoid tissue induced by co-exposure to Asian sand dust and ovalbumin: a study using 3D serial section imaging.” Front Immunol. 2025 Aug 4:16:1578255. doi: 10.3389/fimmu.2025.1578255. eCollection 2025. |
| 10. | 7. Kanda T, Ibrahim OMA, Mori-Ogiwara Y, Yagi-Yaguchi Y, Higa K, Kasamatsu H, Shijo T, Tomida D, Noma H, Shibata S, Dogru M, Yamaguchi T. “Association Between Intracellular Dark Spots on Specular Microscopy and Endothelial Cell Loss After Penetrating Keratoplasty” Am J Ophthalmol. 2025 Dec;280:182-192. doi: 10.1016/j.ajo.2025.08.022. PMID: 40840581 |
| 11. | 8. Yoshimura T, Kamatani T, Ookubo A, Takahashi M, Itoh M, Ebisudani T, Masugi Y, Toyonaga T, Hamamoto J, Saotome K, Sakai K, Yoshihama T, Moritoki N, Shibata S, Yasuda H, Sato T, Sato TA, Aoki D, Yamagami W, Tsunoda T, Chiyoda T. “High-throughput drug screening of clear cell ovarian cancer organoids reveal vulnerability to proteasome inhibitors and dinaciclib and identify AGR2 as a therapeutic target.” Cancer Res Commun. 2025 Jun 3. doi: 10.1158/2767-9764.CRC-25-0024. PMID: 40459063 |
| 12. | Fujiki T, Shiratsuchi H, Mikami Y, Toriumi T, Yonehara Y, Tsuda H. “Calcified tissues induced by inorganic polyphosphate in chondrogenic ATDC5 cells undergo decalcification in the presence of insulin.” J Oral Sci. 2025 Apr 16;67(2):65-70. doi: 10.2334/josnusd.24-0429. Epub 2025 Mar 8. |
| 13. | 9. Hattori Y, Sugiyama H, Miyashita Y, Shibata S, Okaue T, Matsumoto Y, Yamada T, Yamamoto T, Yamaguchi T, Yamazaki K, Kunieda H, Saya H, Matsushita M. “Ambroxol induces myeloma cell death by inhibiting autophagy” Blood Neoplasia. 2025 Apr 3;2(3):100100. doi: 10.1016/j.bneo.2025.100100. PMID: 40575080 |
| 14. | Hiraiwa T, Yoshii S, Kawada J, Sugawara T, Kawasaki T, Shibata S, Shindo T, Fujimori K, Umezawa A, Akutsu H. “A human iPSC-Derived myelination model for investigating fetal brain injuries.” Regen Ther. 2025 Mar 13;29:100-107. doi: 10.1016/j.reth.2025.02.014 PMID: 40162018 |
| 15. | Ariyasu D, Higa D, Tokudome R, Yonemori T, Shimada H, Shibata S, Araki K. “Mice with Heterozygous Deletion of Exon 3 in the Gh Gene Demonstrate Growth Retardation Caused by Reduced Ghrhr mRNA.” Int J Mol Sci. 2025 Jan 26;26(3):1061. doi: 10.3390/ijms26031061. PMID: 39940828 |
| 16. | Matsuo T, Kimura H, Nishijima T, Kiyota Y, Suzuki T, Nagoshi N, Shibata S, Shindo T, Moritoki N, Sasaki M, Noguchi S, Tamada Y, Nakamura M, Iwamoto T. “Peripheral nerve regeneration using a bioresorbable silk fibroin-based artificial nerve conduit fabricated via a novel freeze-thaw process.” Sci Rep. 2025 Jan 30;15(1):3797. doi: 10.1038/s41598-025-88221-y. PMID: 39885362 |
| 17. | Tsujisaka R, Suzuki T, Shibata S, Iwamoto T, Taguchi T, Nakamura M.“Effect of Alaska pollock-gelatin sheet on repair strength and regeneration of nerve.” J Hand Surg Eur Vol. 2025 Jan;50(1):76-84. doi: 10.1177/17531934241251670. PMID: 38780096 |
2024年
| 18. | Ito K, Shinozaki M, Hashimoto S, Saijo Y, Suematsu Y, Tanaka T, Nishi K, Yagi H, Shibata S, Kitagawa Y, Nakamura M, Okano H, Kohyama J, Nagoshi N, “Histological effects of combined therapy involving scar resection, decellularized scaffolds, and human iPSC-NS/PCs transplantation in chronic complete spinal cord injury” Sci Rep. 2024 Dec 28;14(1):31500. doi: 10.1038/s41598-024-82959-7. PMID: 39733145 |
| 19. | Okada K, Ito D, Morimoto S, Kato C, Oguma Y, Warita H, Suzuki N, Aoki M, Kuramoto J, Kobayashi R, Shinozaki M, Ikawa M, Nakahara J, Takahashi S, Nishimoto Y, Shibata S, Okano H. “Multiple lines of evidence for disruption of nuclear lamina and nucleoporins in FUS amyotrophic lateral sclerosis.” Brain. 2024 Sep 23:awae224. doi: 10.1093/brain/awae224. PMID: 39312484 |
| 20. | Yan C, Nakajima M, Ikeda-Imafuku M, Yanagawa M, Hayatsu M, Fukuta T, Shibata S, Mitragotri S, Tabeta K. “Choline and geranate ionic liquid for subgingival biofilm control.” Int J Pharm. 2024 Sep 5;662:124544. doi: 10.1016/j.ijpharm.2024.124544. PMID: 39094920 |
| 21. | Miyaki T, Honma N, Kawasaki Y, Kishi M, Yamaguchi J, Kakuta S, Shindo T, Sugiura M, Trejo JAO, Kaneda H, Omotehara T, Takechi M, Negishi-Koga T, Ishijima M, Aoto K, Iseki S, Kitamura K, Muto S, Amagasa M, Hotchi S, Ogura K, Shibata S, Sakai T, Suzuki Y, Ichimura K. “Ultrastructural analysis of whole glomerulus using array tomography.” J Cell Sci. 2024 Aug 22:jcs.262154. doi: 10.1242/jcs.262154. PMID: 39171439 |
| 22. | Kinashi Y, Tanaka K, Kimura S, Hirota M, Komiyama S, Shindo T, Hashiguchi A, Takahashi D, Shibata S, Karaki SI, Ohno H, Hase K. “Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice.” EBioMedicine. 2024 Aug;106:105256. doi: 10.1016/j.ebiom.2024.105256. PMID: 39059316 |
| 23. | Pinyomahakul J, Ise M, Kawamura M, Yamada T, Okuyama K, Shibata S, Takizawa J, Abe M, Sakimura K, Takebayashi H. “Analysis of Brain, Blood, and Testis Phenotypes Lacking the Vps13a Gene in C57BL/6N Mice.” Int J Mol Sci. 2024 Jul 16;25(14):7776. doi: 10.3390/ijms25147776. PMID: 39063018 |
| 24. | Ginevskaia T, Innokentev A, Furukawa K, Fukuda T, Hayatsu M, Yamashita SI, Inoue K, Shibata S, Kanki T. “Comprehensive analysis of non-selective and selective autophagy in yeast atg mutants and characterization of autophagic activity in the absence of the Atg8 conjugation system.” J Biochem. 2024 Jun 6: mvae042. doi: 10.1093/jb/mvae042. PMID: 38843068 |
| 25. | Furukawa K, Hayatsu M, Okuyama K, Fukuda T, Yamashita SI, Inoue K, Shibata S, Kanki T. “Atg44/Mdi1/mitofissin facilitates Dnm1-mediated mitochondrial fission.” Autophagy. 2024 Jun 4:1-9. doi: 10.1080/15548627.2024.2360345. PMID: 38818923 |
| 26. | Ishiyama S, Hayatsu M, Toriumi T, Tsuda H, Watanabe K, Kasai H, Kishigami S, Mochizuki K, Mikami Y. “Assessing the combined impact of fatty liver‑induced TGF‑β1 and LPS‑activated macrophages in fibrosis through a novel 3D serial section methodology.” Sci Rep. 2024 May 18;14(1):11404. doi: 10.1038/s41598-024-60845-6. |
| 27. | Leventoux N, Morimoto S, Ishikawa M, Nakamura S, Ozawa F, Kobayashi R, Watanabe H, Supakul S, Okamoto S, Zhou Z, Kobayashi H, Kato C, Hirokawa Y, Aiba I, Takahashi S, Shibata S, Takao M, Yoshida M, Endo F, Yamanaka K, Kokubo Y, Okano H. “Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes” Acta Neuropathol. 2024 May 15;147(1):84. doi: 10.1007/s00401-024-02734-w. PMID: 38750212 |
| 28. | Wada M, Higa T, Katoh K, Moritoki N, Nakai T, Nishino Y, Miyazawa A, Shibata S, Mineyuki Y. “Chloroplast-actin filaments decide the direction of chloroplast avoidance movement under strong light in Arabidopsis thaliana.” J Plant Res. 2024 Apr 10. doi: 10.1007/s10265-024-01540-5. PMID: 38598067 |
| 29. | Arai J, Hayakawa Y, Tateno H, Murakami K, Hayashi T, Hata M, Matsushita Y, Kinoshita H, Abe S, Kurokawa K, Oya Y, Tsuboi M, Ihara S, Niikura R, Suzuki N, Iwata Y, Shiokawa T, Shiomi C, Uekura C, Yamamoto K, Fujiwara H, Kawamura S, Nakagawa H, Mizuno S, Kudo T, Takahashi S, Ushiku T, Hirata Y, Fujii C, Nakayama J, Shibata S, Woods S, Worthley DL, Hatakeyama M, Wang TC, Fujishiro M. “Impaired glycosylation of gastric mucins drives gastric tumorigenesis and serves as a novel therapeutic target.” Gastroenterology 2024 Apr 5:S0016-5085(24)00363-9. doi: 10.1053/j.gastro.2024.03.037. |
| 30. | Tashiro S, Shibata S, Nagoshi N, Zhang L, Yamada S, Tsuji T, Nakamura M, Okano H. “Do Pharmacological Treatments Act in Collaboration with Rehabilitation in Spinal Cord Injury Treatment? A Review of Preclinical Studies” Cells 2024 Feb 27;13(5):412. doi: 10.3390/cells13050412. PMID: 38474376 |
| 31. | Supakul S, Murakami R, Oyama C, Shindo T, Hatakeyama Y, Itsuno M, Bannai H, Shibata S, Maeda S, Okano H. “Mutual interaction of neurons and astrocytes derived from iPSCs with APP V717L mutation developed the astrocytic phenotypes of Alzheimer's disease.” Inflamm Regen. 2024 Feb 28;44(1):8. doi: 10.1186/s41232-023-00310-5. PMID: 38419091 |
| 32. | Saijo Y, Nagoshi N, Kawai M, Kitagawa T, Suematsu Y, Ozaki M, Shinozaki M, Kohyama J, Shibata S, Takeuchi K, Nakamura M, Yuzaki M, Okano H. “Human-induced pluripotent stem cell-derived neural stem/progenitor cell ex vivo gene therapy with synaptic organizer CPTX for spinal cord injury.” Stem Cell Rep. 2024 Mar 12;19(3):383-398. doi: 10.1016/j.stemcr.2024.01.007. PMID: 38366597 |
| 33. | Nishijima T, Okuyama K, Shibata S*, Kimura H, Shinozaki M, Ouchi T, Mabuchi Y, Ohno T, Nakayama J, Hayatsu M, Uchiyama K, Shindo T, Niiyama E, Toita S, Kawada J, Iwamoto T, Nakamura M, Okano H, Nagoshi N*, “Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury.” Inflamm Regen. 2024 Feb 13;44(1):6. doi: 10.1186/s41232-024-00319-4. PMID: 38347645 (*co-corresponding author) |
| 34. | Yoshida T, Tashiro S, Nagoshi N, Shinozaki M, Shibata T, Inoue M, Ogawa S, Shibata S, Tsuji T, Okano H, Nakamura M. “Chronic Spinal Cord Injury Regeneration with Combined Therapy Comprising Neural Stem/Progenitor Cell Transplantation, Rehabilitation, and Semaphorin 3A Inhibitor.” eNeuro. 2024 Feb 13;11(2):ENEURO.0378-23.2024. doi: 10.1523/ENEURO.0378-23.2024. PMID: 38262737 |
2023年
| 35. | Tsurisaki E, Nameta M, Shibata S, Hirayama S, Iwai J, Ohashi R, Otani M, Ito Y, Matsumura N, Moriguchi Y, "Cytological Analysis of Male-Sterile MS5 Japanese Cedar (Cryptomeria japonica D. Don) and Comparison with Other Male-Sterile Mutants" Journal of Plant Biology, 23 December 2023, Volume 67, pages 11–23, doi: 10.1007/s12374-023-09415-3 |
| 36. | Uemichi K, Mikami Y, Watanabe T, Shinozuka K, Tonogi M, Tsuda H. “Histone-deacetylase-inhibitory effects of periodontopathic-bacterial metabolites induce human gingival epithelial Ca9-22 cell death. Odontology.” 2023 Jul;111(3):658-667. doi: 10.1007/s10266-022-00775-9. Epub 2022 Dec 8. PMID: 36482237. |
| 37. | Sasaki M, Mitsuhashi T, Goto F, Shibata S, Kubo K, Oku S, Owashi A, Takahashi T. “Maternal immune activation by poly (I:C) exposure causes cerebral cortical dysgenesis through dysregulated cell cycle kinetics of neural stem/progenitor cells” Dev Neurosci. Jun 2023, 45 (3) , pp.115-125, doi: DOI10.1159/000529317 |
| 38. | Suematsu Y, Nagoshi N, Shinozaki M, Kase Y, Saijo Y, Hashimoto S, Shibata T, Kajikawa K, Kamata Y, Ozaki M, Yasutake K, Shindo T, Shibata S, Matsumoto M, Nakamura M, Okano H. “Hepatocyte growth factor pretreatment boosts functional recovery after spinal cord injury through human iPSC-derived neural stem/progenitor cell transplantation.” Inflamm Regen. 2023 Oct 16;43(1):50. doi: 10.1186/s41232-023-00298-y. PMID: 37845736 |
| 39. | Iga T, Kobayashi H, Kusumoto D, Sanosaka T, Fujita N, Tai-Nagara I, Ando T, Takahashi T, Matsuo K, Hozumi K, Ito K, Ema M, Miyamoto T, Matsumoto M, Nakamura M, Okano H, Shibata S, Kohyama J, Kim KK, Takubo K, Kubota Y. “Spatial heterogeneity of bone marrow endothelial cells unveils a distinct subtype in the epiphysis” Nat Cell Biol. 2023 Oct;25(10):1415-1425. doi: 10.1038/s41556-023-01240-7. PMID: 37798545 |
| 40. | Watanabe K, Horie M, Hayatsu M, Mikami Y, Sato N. “Spatiotemporal expression patterns of R-spondins and their receptors, Lgrs, in the developing mouse telencephalon. Gene Expr Patterns.” 2023 Sep;49:119333. doi: 10.1016/j.gep.2023.119333. Epub 2023 Aug 29. PMID: 37651925. |
| 41. | Pieczonka K, Nakashima H, Nagoshi N, Yokota K, Hong J, Badner A, Chio JCT, Shibata S, Khazaei M, Fehlings MG. “Human Spinal Oligodendrogenic Neural Progenitor Cells Enhance Pathophysiological Outcomes and Functional Recovery in a Clinically Relevant Cervical Spinal Cord Injury Rat Model.” Stem Cells Transl Med. 2023 Aug 24:szad044. doi: 10.1093/stcltm/szad044. PMID: 37616288 |
| 42. | Umeda S, Sujino T, Miyamoto K, Yoshimatsu Y, Harada Y, Nishiyama K, Aoto Y, Adachi K, Hayashi N, Amafuji K, Moritoki N, Shibata S, Sasaki N, Mita M, Tanemoto S, Ono K, Mikami Y, Sasabe J, Takabayashi K, Hosoe N, Suzuki T, Sato T, Atarashi K, Teratani T, Ogata H, Nakamoto N, Shiomi D, Ashida H, Kanai T. “D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease.” Cell Mol Gastroenterol Hepatol. 2023 Aug 9:S2352-345X(23)00148-0. doi: 10.1016/j.jcmgh.2023.08.002. PMID: 37567385 |
| 43. | Omagari D, Toriumi T, Tsuda H, Hayatsu M, Watanabe K, Mizutami Y, Honda M, Mikami Y. “Inductive effect of SORT1 on odontoblastic differentiation of human dental pulp-derived stem cells. Differentiation.” 2023 Sep-Oct:133:88-97. doi: 10.1016/j.diff.2023.08.001. Epub 2023 Aug 9. PMID: 37579565. |
| 44. | Kakui H, Ujino-Ihara T, Hasegawa Y, Tsurisaki E, Futamura N, Iwai J, Higuchi Y, Fujino T, Suzuki Y, Kasahara M, Yamaguchi K, Shigenobu S, Otani M, Nakano M, Nameta M, Shibata S, Ueno S, Moriguchi Y. “A single-nucleotide substitution of CjTKPR1 determines pollen production in the gymnosperm plant Cryptomeria japonica.” PNAS Nexus. 2023 Aug 8;2(8): pgad236. doi: 10.1093/pnasnexus/pgad236. eCollection 2023 Aug. PMID: 37559748 |
| 45. | Takeya H, Itai S, Kimura H, Kurashina Y, Amemiya T, Nagoshi N, Iwamoto T, Sato K, Shibata S, Matsumoto M, Onoe H, Nakamura M. “Schwann cell-encapsulated chitosan-collagen hydrogel nerve conduit promotes peripheral nerve regeneration in rodent sciatic nerve defect models.” Sci Rep. 2023 Jul 24;13(1):11932. doi: 10.1038/s41598-023-39141-2. PMID: 37488180 |
| 46. | Ansai O, Hayashi R, Katsumi T, Okuyama K, Shibata S, Shinkuma S, Ito M, Abe R. “Atypical epidermolytic palmoplantar keratoderma is a minimal phenotypic variant of epidermolytic ichthyosis: A new insight from ultrastructural findings.” J Eur Acad Dermatol Venereol. 2023 Jul 17. doi: 10.1111/jdv.19357. Online ahead of print. PMID: 37460199 |
| 47. | Tani H, Kobayashi E, Yagi S, Tanaka K, Kameda-Haga K, Shibata S, Moritoki N, Takatsuna K, Moriwaki T, Sekine O, Umei TC, Morita Y, Soma Y, Kishino Y, Kanazawa H, Fujita J, Hattori S, Fukuda K, Tohyama S. “Heart-derived collagen promotes maturation of engineered heart tissue.” Biomaterials. 2023 Aug;299:122174. doi: 10.1016/j.biomaterials.2023.122174. PMID: 37285642 |
| 48. | Fukuda T, Furukawa K, Maruyama T, Yamashita SI, Noshiro D, Song C, Ogasawara Y, Okuyama K, Alam JM, Hayatsu M, Saigusa T, Inoue K, Ikeda K, Takai A, Chen L, Lahiri V, Okada Y, Shibata S, Murata K, Klionsky DJ, Noda NN, Kanki T. “The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.” Mol Cell. 2023 Jun 15;83(12):2045-2058.e9. doi: 10.1016/j.molcel.2023.04.022. PMID: 37192628 |
| 49. | Hashimoto S, Nagoshi N, Shinozaki M, Nakanishi K, Suematsu Y, Shibata T, Kawai M, Kitagawa T, Ago K, Kamata Y, Yasutake K, Koya I, Ando Y, Minoda A, Shindo T, Shibata S, Matsumoto M, Nakamura M, Okano H. “Microenvironmental modulation in tandem with human stem cell transplantation enhances functional recovery after chronic complete spinal cord injury.” Biomaterials. 2023 Apr ;295:122002. doi: 10.1016/j.biomaterials.2023.122002. PMID: 36736008 |
| 50. | Mitsuhashi T, Hattori S, Fujimura K, Shibata S, Miyakawa T, Takahashi T. “In utero exposure to valproic acid throughout pregnancy causes phenotypes of autism in offspring mice.” Dev Neurosci. 2023;45(5):223-233. doi: 10.1159/000530452. PMID: 37044070 |
| 51. | Natsui K, Tsuchiya A, Imamiya R, Osada-Oka M, Ishii Y, Koseki Y, Takeda N, Tomiyoshi K, Yamazaki F, Yoshida Y, Ohashi R, Ling Y, Ueda K, Moritoki N, Sato K, Nakajima T, Hasegawa Y, Okuda S, Shibata S, Terai S. “Escherichia coli-derived outer-membrane vesicles induce immune activation and progression of cirrhosis in mice and humans.” Liver Int. 2023 Feb 8. doi: 10.1111/liv.15539. PMID: 36751961 |
| 52. | Shibata T, Tashiro S, Shibata S, Shinozaki M, Shindo T, Hashimoto S, Kawai M, Kitagawa T, Ago K, Matsumoto M, Nakamura M, Okano H, Nagoshi N. “Rehabilitative Training Enhances Therapeutic Effect of Human-iPSC-Derived Neural Stem/Progenitor Cells Transplantation in Chronic Spinal Cord Injury.” Stem Cells Transl Med. 2023 Mar 3;12(2):83-96. doi: 10.1093/stcltm/szac089. PMID: 36647673 |
2022年
| 53. | Namiki J, Suzuki S, Shibata S, Kubota Y, Kaneko N, Yoshida K, Yamaguchi R, Matsuzaki Y, Masuda T, Ishihama Y, Sawamoto K, Okano H. “Chitinase-like protein 3: A novel niche factor for mouse neural stem cells.” Stem Cell Rep. 2022 Dec 13;17(12):2704-2717. doi: 10.1016/j.stemcr.2022.10.012. PMID: 36368330 |
| 54. | Uehara N, Kyumoto-Nakamura Y, Mikami Y, Hayatsu M, Sonoda S, Yamaza T, Kukita A, Kukita T. “miR-92a-3p encapsulated in bone metastatic mammary tumor cell-derived extracellular vesicles modulates mature osteoclast longevity. Cancer Sci.” 2022 Dec;113(12):4219-4229. doi: 10.1111/cas.15557. Epub 2022 Sep 27. PMID: 36053115; PMCID: PMC9746050. |
| 55. | Shimada H, Sato Y, Sasaki T, Shimozawa A, Imaizumi K, Shindo T, Miyao S, Kiyama K, Kondo T, Shibata S, Ishii S, Kuromitsu J, Aoyagi H, Ito D, Okano H. “A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer.” Cell Reports Methods. 2022 Sep 8;2(9):100289. doi: 10.1016/j.crmeth.2022.100289. eCollection 2022 Sep 19. PMID: 36160042 |
| 56. | Geberetsadik G, Inaizumi A, Nishiyama A, Yamaguchi T, Hamamoto H, Panthee S, Tamaru A, Hayatsu M, Mizutani Y, Kaboso SA, Hakamata M, Ilinov A, Ozeki Y, Tateishi Y, Sekimizu K, Matsumoto S. “Lysocin E Targeting Menaquinone in the Membrane of Mycobacterium tuberculosis Is a Promising Lead Compound for Antituberculosis Drugs. Antimicrob Agents Chemother.” 2022 Sep 20;66(9):e0017122. doi: 10.1128/aac.00171-22. Epub 2022 Aug 15. PMID: 35969044; PMCID: PMC9487456. |
| 57. | Ago K, Nagoshi N, Imaizumi K, Kitagawa T, Kawai M, Kajikawa K, Shibata R, Kamata Y, Kojima K, Shinozaki M, Kondo T, Iwano S, Miyawaki A, Ohtsuka M, Bito H, Kobayashi K, Shibata S, Shindo T, Kohyama J, Matsumoto M, Nakamura M, Okano H. “A non-invasive system to monitor in vivo neural graft activity after spinal cord injury.” Commun Biol. 2022 Aug 10;5(1):803. doi: 10.1038/s42003-022-03736-8. PMID: 35948599 |
| 58. | Yoshioka N, Kurose M, Yano M, Tran DM, Okuda S, Mori-Ochiai Y, Horie M, Nagai T, Nishino I, Shibata S, Takebayashi H. “Isoform-specific mutation in Dystonin-b gene causes late-onset protein aggregate myopathy and cardiomyopathy.” Elife. 2022 Aug 9;11:e78419. doi: 10.7554/eLife.78419. PMID: 35942699 |
| 59. | Kanzaki S, Shibata S, Nakamura M, Ozaki M, Okano H. “In Vivo Imaging Analysis of an Inner Ear Drug Delivery in Mice: Comparison of Inner Ear Drug Concentrations Over Time.” Methods Mol Biol. 2022 2524:327-332. doi: 10.1007/978-1-0716-2453-1_26. PMID: 35821484 |
| 60. | Tsuruta S, Kawasaki T, Machida M, Iwatsuki K, Inaba A, Shibata S, Shindo T, Nakabayashi K, Hakamada K, Umezawa A, Akutsu H. “Development of Organoids With Resident Tissue Macrophages as a Model of Intestinal Immune Responses.” Cell Mol Gastroenterol Hepatol. 2022 Jun 26:S2352-345X(22)00149-7. doi: 10.1016/j.jcmgh.2022.06.006. PMID: 35760286 |
| 61. | Saeki T, Yoshimatsu S, Ishikawa M, Hon CC, Koya I, Shibata S, Hosoya M, Saegusa C, Ogawa K, Shin JW, Fujioka M, Okano H. “Critical roles of FGF, RA, and WNT signalling in the development of the human otic placode and subsequent lineages in a dish.” Regen Ther. 2022 May 16;20:165-186. doi: 10.1016/j.reth.2022.04.008. eCollection 2022 Jun. PMID: 35620640 |
| 62. | Yanagisawa T, Ouchi T, Shibata S, Negishi T, Okano H. “Glycosaminoglycans promote osteogenesis from human induced pluripotent stem cells via neural crest induction.” Biochem Biophys Res Commun. 2022 Mar 3;603:49-56. doi: 10.1016/j.bbrc.2022.03.002. PMID: 35278879 |
| 63. | Shibata R, Nagoshi N, Kajikawa K, Ito S, Shibata S, Shindo T, Khazaei M, Nori S, Kohyama J, Fehlings MG, Matsumoto M, Nakamura M, Okano H. “Administration of C5a receptor antagonist improves the efficacy of human iPSCs-derived NS/PC transplantation in the acute phase of spinal cord injury.” J Neurotrauma. 2022 Feb 24. doi: 10.1089/neu.2021.0225. PMID: 35196890 |
| 64. | Haraguchi T, Koujin T, Shindo T, Bilir Ş, Osakada H, Nishimura K, Hirano Y, Asakawa H, Mori C, Kobayashi S, Okada Y, Chikashige Y, Fukagawa T, Shibata S, Hiraoka Y. “Transfected plasmid DNA is incorporated into the nucleus via nuclear envelope reformation at telophase.” Commun Biol. 2022 Jan 20;5(1):78. doi: 10.1038/s42003-022-03021-8. PMID: 35058555 |
| 65. | Sato M, Morita K, Azumi R, Mizutani Y, Hayatsu M, Ushiki T, Terai shuji. “Diet-related changes of basal lamina fenestrations in the villous epithelium of the rat small intestine: Statistical analysis on scanning electron microscopy.” Biomed Res. 43(1):11-22. doi:10.2220/biomedres.43.11 2022. 1 |
| 66. | Kitagawa T, Nagoshi N, Kamata Y, Kawai M, Ago K, Kajikawa K, Shibata R, Sato Y, Imaizumi K, Shindo T, Shinozaki M, Kohyama J, Shibata S, Matsumoto M, Nakamura M, Okano H. “Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury.” Stem Cell Rep 2022 Jan 11;17(1):127-142. doi: 10.1016/j.stemcr.2021.12.005. PMID: 35021049 |
2021年
| 67. | Sato Y, Atarashi K, Plichta DR, Arai Y, Sasajima S, Kearney SM, Suda W, Takeshita K, Sasaki T, Okamoto S, Skelly AN, Okamura Y, Vlamakis H, Li Y, Tanoue T, Takei H, Nittono H, Narushima S, Irie J, Itoh H, Moriya K, Sugiura Y, Suematsu M, Moritoki N, Shibata S, Littman DR, Fischbach MA, Uwamino Y, Inoue T, Honda A, Hattori M, Murai T, Xavier RJ, Hirose N, Honda K “Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians” Nature. 2021 Nov;599(7885):458-464. doi: 10.1038/s41586-021-03832-5. PMID: 34325466 |
| 68. | Kawai M, Imaizumi K, Ishikawa M, Shibata S, Shinozaki M, Shibata T, Hashimoto S, Kitagawa T, Ago K, Kajikawa K, Shibata R, Kamata Y, Ushiba J, Koga K, Furue H, Matsumoto M, Nakamura M, Nagoshi N, Okano H. “Long-term selective stimulation of transplanted neural stem/progenitor cells for spinal cord injury improves locomotor function” Cell Rep 2021 Nov 23;37(8):110019. doi: 10.1016/j.celrep.2021.110019. PMID: 34818559 |
| 69. | Masuda S, Suzuki T, Shibata S, Moritoki N, Abe Y, Chen X, Mizuno Y, Nishiguchi A, Kimura H, Matsumura N, Iwamoto T, Taguchi T, Matsumoto M, Nakamura M. “A Novel Alaska Pollock Gelatin Sealant Shows Higher Bonding Strength and Nerve Regeneration Comparable to That of Fibrin Sealant in a Cadaveric Model and a Rat Model” Plast Reconstr Surg. 2021 Nov 1;148(5):742e-752e. doi: 10.1097/PRS.0000000000008489. PMID: 34705777 |
| 70. | Yang F, Hayashi I, Sato S, Saijo-Ban Y, Yamane M, Fukui M, Shimizu E, He J, Shibata S, Mukai S, Asai K, Ogawa M, Lan Y, Zeng Q, Hirakata A, Tsubota K, Ogawa Y. “Eyelid blood vessel and meibomian gland changes in a sclerodermatous chronic GVHD mouse model” Ocul Surf. 2021 Oct 26:S1542-0124(21)00123-3. doi: 10.1016/j.jtos.2021.10.006. Online ahead of print. PMID: 34715372 |
| 71. | Sharp MM, Cassidy J, Thornton T, Lyles J, Keable A, Gatherer M, Yasui M, Abe Y, Shibata S, Weller RO, Górecki DC, Carare RO. “The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix-significance for protein elimination failure arteriopathies.” Acta Neuropathol Commun. 2021 Oct 21;9(1):171. doi: 10.1186/s40478-021-01274-8. PMID: 34674769 |
| 72. | Li Y, Kanzaki S, Shibata S, Nakamura M, Ozaki M, Okano H, Ogawa K “Comparison of Drug Availability in the Inner Ear After Oral, Transtympanic, and Combined Administration” Front Neurol. 2021 Aug 19;12:641593. doi: 10.3389/fneur.2021.641593. eCollection 2021. PMID: 34497573 |
| 73. | Simankova A, Bizen N, Saitoh S, Shibata S, Ohno N, Abe M, Sakimura K, Takebayashi H “Ddx20, DEAD box helicase 20, is essential for the differentiation of oligodendrocyte and maintenance of myelin gene expression” Glia. 2021 Jul 7. doi: 10.1002/glia.24058. PMID: 34231259 |
| 74. | Fujiwara Y, Murofushi T, Koshi R, Mikami Y, Tsuda H. “Reactive oxygen species-dependent release of damage-associated molecular patterns from human gingival epithelial Ca9-22 cells during butyrate or propionate exposure.” J Oral Sci. 2021 Mar 31;63(2):195-197. doi: 10.2334/josnusd.20-0411. Epub 2020 Dec 30. PMID: 33390461. |
| 75. | Kamata Y, Isoda M, Sanosaka T, Shibata R, Ito S, Okubo T, Shinozaki M, Inoue M, Koya I, Shibata S, Shindo T, Matsumoto M, Nakamura M, Okano H, Nagoshi N, Kohyama J “A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury” Stem Cells Transl Med. 2021 Mar;10(3):398-413. doi: 10.1002/sctm.20-0269. PMID: 33226180 |
| 76. | Suzuki M, Saito-Adachi M, Arai Y, Fujiwara Y, Takai E, Shibata S, Seki M, Rokutan H, Maeda D, Horie M, Suzuki Y, Shibata T, Kiyono T, Yachida S “E74-like factor 3 is a key regulator of epithelial integrity and immune response genes in biliary tract cancer” Cancer Res. Cancer Res. 2021 Jan 15;81(2):489-500. doi: 10.1158/0008-5472.CAN-19-2988. PMID: 33293429 |
| 77. | Matsugishi A, Aoki-Nonaka Y, Yokoji-Takeuchi M, Yamada-Hara M, Mikami Y, Hayatsu M, Terao Y, Domon H, Taniguchi M, Takahashi N, Yamazaki K, Tabeta K. “Rice peptide with amino acid substitution inhibits biofilm formation by Porphyromonas gingivalis and Fusobacterium nucleatum. Arch Oral Biol.” 2021 Jan:121:104956. doi: 10.1016/j.archoralbio.2020.104956. Epub 2020 Oct 30. PMID: 33157493. |
2020年
| 78. | Nagai N, Kawashima H, Toda E, Homma K, Osada H, Guzman NA, Shibata S, Uchiyama Y, Okano H, Tsubota K, Ozawa Y. “Renin-angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models.” Commun Biol. 2020 Dec 9;3(1):767. doi: 10.1038/s42003-020-01483-2. PMID: 33299105 |
| 79. | Suzuki T, Adachi S, Kikuguchi C, Shibata S, Nishijima S, Kawamoto Y, Iizuka Y, Koseki H, Okano H, Natsume T, Yamamoto T. “Regulation of Fetal Genes by Transitions among RNA-Binding Proteins during Liver Development.” Int J Mol Sci. 2020 Dec 7;21(23):9319. doi: 10.3390/ijms21239319. PMID: 33297405 |
| 80. | Kajikawa K, Imaizumi K, Shinozaki M, Shibata S, Shindo T, Kitagawa T, Shibata R, Kamata Y, Kojima K, Nagoshi N, Matsumoto M, Nakamura M, Okano H. “Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells.” Mol Brain. 2020 Sep 3;13(1):120. doi: 10.1186/s13041-020-00662-w. PMID: 32883317 |
| 81. | Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Shibata S, Miyamoto K, Ishigame H, Chu PS, Sujino T, Suda W, Hattori M, Matsui M, Okada T, Okano H, Inoue M, Yada T, Kitagawa Y, Yoshimura A, Tanida M, Tsuda M, Iwasaki Y, Kanai T. “The liver-brain-gut neural arc maintains the Treg cell niche in the gut.” Nature. 2020 Sep;585(7826):591-596. doi: 10.1038/s41586-020-2425-3. PMID: 32526765 |
| 82. | Ishiwa S, Kamei K, Tanase-Nakao K, Shibata S, Matsunami K, Takeuchi I, Sato M, Ishikura K, Narumi S. “A girl with MIRAGE syndrome who developed steroid-resistant nephrotic syndrome: a case report.” BMC Nephrol. 2020 Aug 12;21(1):340. doi: 10.1186/s12882-020-02011-4. PMID: 32787808 |
| 83. | Takahashi M, Misaki M, Shibata S, Iga T, Shindo T, Tai-Nagara I, Hirata A, Ogawa M, Miyamoto T, Nakagawa T, Ema M, Ichiyama Y, Shima DT, Hozumi K, Nishimura S, Kubota Y. “Macrophages fine-tune pupil shape during development.” Dev Biol. 2020 Aug 15;464(2):137-144. doi: 10.1016/j.ydbio.2020.06.004. PMID: 32565279 |
| 84. | Okazaki I*, Shibata S*, Ando W, Yanagawa T, Yokomori H, Sonoda A, Suzuki N, Yamanouchi E, Okada S, Kamikura S, Hachimura K, Takaki T, Otori K, Suzuki Y, Okano H, Inagaki Y. (*equally contributed first author) “Sequential Matrix Metalloproteinase-1 Expression Triggered by Infiltrating Monocytic Lineage Cells Modulates Pathophysiological Aspects of Human Nonalcoholic Steatohepatitis” Metalloproteinases Med. 2020 Jul 21; Volume 2020:7 Pages 1-13, doi: 10.2147/MNM.S252991 |
| 85. | Yamane M, Sato S, Shimizu E, Shibata S, Hayano M, Yaguchi T, Kamijuku H, Ogawa M, Suzuki T, Mukai S, Shimmura S, Okano H, Takeuchi T, Kawakami Y, Ogawa Y, Tsubota K. “Senescence-associated secretory phenotype promotes chronic ocular graft-vs-host disease in mice and humans” FASEB J. 2020 Aug;34(8):10778-10800. doi: 10.1096/fj.201900218R. PMID: 32619061 |
| 86. | Hirano Y, Kinugasa Y, Osakada H, Shindo T, Kubota Y, Shibata S, Haraguchi T, Hiraoka Y. “Lem2 and Lnp1 maintain the membrane boundary between the nuclear envelope and endoplasmic reticulum.” Commun Biol. 2020 Jun 1;3(1):276. doi: 10.1038/s42003-020-0999-9. PMID: 32483293 |
| 87. | Yamaguchi T, Higa K, Yagi-Yaguchi Y, Ueda K, Noma H, Shibata S, Nagai T, Tomida D, Yasu-Mimura R, Ibrahim O, Matoba R, Tsubota K, Hamrah P, Yamada J, Kanekura K, Shimazaki J. “Pathological processes in aqueous humor due to iris atrophy predispose to early corneal graft failure in humans and mice.” Science Advances. 2020 May 13;6(20):eaaz5195. doi: 10.1126/sciadv.aaz5195. eCollection 2020 May. PMID: 32426498 |
| 88. | Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H. “YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology.” Nat Commun. 2020 Jan 24;11(1):507. doi: 10.1038/s41467-020-14353-6. PMID: 31980612 |
| 89. | Khazaei M, Ahuja CS, Nakashima H, Nagoshi N, Li L, Wang J, Chio J, Badner A, Seligman D, Ichise A, Shibata S, Fehlings MG “GDNF rescues the fate of neural progenitor grafts by attenuating Notch signals in the injured spinal cord in rodents.” Sci Transl Med. 2020 Jan 8;12(525). pii: eaau3538. doi: 10.1126/scitranslmed.aau3538. PMID: 31915299 |
| 90. | Saeki T, Hosoya M, Shibata S, Okano H, Fujioka M, Ogawa K. “Distribution of tight junctions in the primate cochlear lateral wall.” Neurosci Lett. 2020 Jan 19;717:134686. doi: 10.1016/j.neulet.2019.134686. PMID: 31838016 |
2019年
| 91. | Mohan S, Coto Hernández I, Selig MK, Shibata S, Jowett N. “Stain-Free Resolution of Unmyelinated Axons in Transgenic Mice Using Fluorescence Microscopy.” J Neuropathol Exp Neurol. 2019 Dec 1;78(12):1178-1180. doi: 10.1093/jnen/nlz099. PMID: 31642916 |
| 92. | Serizawa T, Isotani A, Matsumura T, Nakanishi K, Nonaka S, Shibata S, Ikawa M, Okano H. “Developmental analyses of mouse embryos and adults using a non-overlapping tracing system for all three germ layers.” Development. 2019 Nov 4;146(21). pii: dev174938. doi: 10.1242/dev.174938. PMID: 31597657 |
| 93. | Ariyasu D, Kubo E, Higa D, Shibata S, Takaoka Y, Sugimoto M, Imaizumi K, Hasegawa T, Araki K. “Decreased Activity of the Ghrhr and Gh Promoters Causes Dominantly Inherited GH Deficiency in Humanized GH1 Mouse Models.” Endocrinology. 2019 Nov 1;160(11):2673-2691. doi: 10.1210/en.2019-00306. PMID: 31436800 |
| 94. | Hoshino Y, Nishide K, Nagoshi N, Shibata S, Moritoki N, Kojima K, Tsuji O, Matsumoto M, Kohyama J, Nakamura M, Okano H. “The adeno-associated virus rh10 vector is an effective gene transfer system for chronic spinal cord injury.” Scientific Reports. 2019 Jul 8;9(1):9844. doi: 10.1038/s41598-019-46069-z. PMID: 31285460 |
| 95. | Li Y, Kanzaki S, Shibata S, Nakamura M, Ozaki M, Okano H, Ogawa K. “Comparison of inner ear drug availbability of combined treatment with systemic or local drug injections alone.” Neurosci Res. 2019 Jul 3. pii: S0168-0102(19)30250-0. doi: 10.1016/j.neures.2019.07.001. PMID: 31278973 |
| 96. | Shibata S*, Iseda T, Mitsuhashi T, Oka A, Shindo T, Moritoki N, Nagai T, Otsubo S, Inoue T, Sasaki E, Akazawa C, Takahashi T, Schalek R, Lichtman JW, Okano H*, “Large-area fluorescence and electron microscopic correlative imaging with multibeam scanning electron microscopy” Front Neural Circuits, 2019 May 8;13:29. doi: 10.3389/fncir.2019.00029. eCollection 2019. PMID: 31133819 (*co-corresponding author) |
| 97. | Kirihara T, Luo Z, Chow SY, Misawa R, Kawada J, Shibata S, Khoyratee F, Vollette CA, Levi T, Fujii T, Ikeuchi Y “A human induced pluripotent stem cell-derived tissue model of a white matter tract connecting two cerebral regions” iScience 2019 Apr 26;14:301-311. doi: 10.1016/j.isci.2019.03.012. PMID: 31006610 |
| 98. | Yamazaki Y, Abe Y, Shibata S, Shindo T, Fujii S, Ikenaka K, Tanaka KF. “Region- and cell type-specific facilitation of synaptic function at destination synapses induced by oligodendrocyte depolarization.” J Neurosci. 2019 May 22;39(21):4036-4050. doi: 10.1523/JNEUROSCI.1619-18.2019. PMID: 30862665 |
| 99. | Kinugasa Y, Hirano Y, Sawai M, Ohno Y, Shindo T, Asakawa H, Chikashige Y, Shibata S, Kihara A, Haraguchi T, Hiraoka Y. “Very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function” J Cell Sci. 2019 May 15;132(10). pii: jcs229021. doi: 10.1242/jcs.229021. PMID: 30975915 |
| 100. | Abe Y, Komaki Y, Seki F, Shibata S, Okano H, Tanaka KF. “Correlative study using structural MRI and super-resolution microscopy to detect structural alterations induced by long-term optogenetic stimulation of striatal medium spiny neurons.” Neurochem Int. 2019 May;125:163-174. doi: 10.1016/j.neuint.2019.02.017. PMID: 30825601 |
| 101. | Miki F, Maruyama T, Miyazaki K, Takao T, Yoshimasa Y, Katakura S, Hihara H, Uchida S, Masuda H, Uchida H, Nagai T, Shibata S, Tanaka M., “The orientation of a decellularized uterine scaffold determines the tissue topology and architecture of the regenerated uterus in rats” Biol Reprod. 2019 May 1;100(5):1215-1227. doi: 10.1093/biolre/ioz004. PMID: 30649202 |
| 102. | Suzuki N, Yamaguchi T, Shibata S, Nagai T, Noma H, Tsubota K, Shimazaki J. “Cytokine Levels in the Aqueous Humor Are Associated With Corneal Thickness in Eyes With Bullous Keratopathy.” Am J Ophthalmol. 2019 Feb;198:174-180. doi: 10.1016/j.ajo.2018.10.008. PMID: 30316668 |
2018年
| 103. | Ito S, Nagoshi N, Tsuji O, Shibata S, Shinozaki M, Kawabata S, Kojima K, Yasutake K, Hirokawa T, Matsumoto M, Takei K, Nakamura M, and Okano H. "LOTUS inhibits neuronal apoptosis and promotes tract regeneration in contusive spinal cord injury model mice" eNeuro. 2018 Dec 14;5(5). pii: ENEURO.0303-18.2018. doi: 10.1523/ENEURO.0303-18.2018. eCollection 2018 Sep-Oct. PMID: 30560203 |
| 104. | Okubo T, Nagoshi N, Kohyama J, Tsuji O, Shinozaki M, Shibata S, Kase Y, Matsumoto M, Nakamura M, Okano H. “Treatment with a Gamma-Secretase Inhibitor Promotes Functional Recovery in Human iPSC- Derived Transplants for Chronic Spinal Cord Injury.” Stem Cell Reports. 2018 Dec 11;11(6):1416-1432. doi: 10.1016/j.stemcr.2018.10.022. PMID: 30503258 |
| 105. | Nori S, Khazaei M, Ahuja CS, Yokota K, Ahlfors JE, Liu Y, Wang J, Shibata S, Chio J, Hettiaratchi MH, Führmann T, Shoichet MS, Fehlings MG, “Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury.” Stem Cell Reports. 2018 Dec 11;11(6):1433-1448. doi: 10.1016/j.stemcr.2018.10.017. PMID: 30472009 |
| 106. | Kojima K, Miyoshi H, Nagoshi N, Kohyama J, Itakura G, Kawabata S, Ozaki M, Iida T, Sugai K, Ito S, Fukuzawa R, Yasutake K, Renault-Mihara F, Shibata S, Matsumoto M, Nakamura M, Okano H. “Selective Ablation of Tumorigenic Cells Following Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in Spinal Cord Injury.” Stem Cells Transl Med. 2018 Nov 28. doi: 10.1002/sctm.18-0096. PMID: 30485733 |
| 107. | Matsuo K, Ji S, Miya A, Yoda M, Hamada Y, Tanaka T, Takao-Kawabata R, Kawaai K, Kuroda Y, Shibata S, “Innervation of the tibial epiphysis through the intercondylar foramen.” Bone. 2018 Nov 13;120:297-304. doi: 10.1016/j.bone.2018.11.007. PMID: 30439572 |
| 108. | Sakai T, Hata J, Ohta H, Shintaku Y, Kimura N, Ogawa Y, Sogabe K, Mori S, Okano HJ, Hamada Y, Shibata S, Okano H, Oishi K, “The Japan Monkey Centre Primates Brain Imaging Repository for comparative neuroscience: an archive of digital records including records for endangered species.” Primates. 2018 Nov;59(6):553-570. doi: 10.1007/s10329-018-0694-3. PMID: 30357587 |
| 109. | Nagoshi N, Khazaei M, Ahlfors JE, Ahuja CS, Nori S, Wang J, Shibata S, Fehlings MG. "Human spinal oligodendrogenic neural progenitor cells promote functional recovery after spinal cord injury by axonal remyelination and tissue sparing" Stem Cells Transl Med. 2018 Nov;7(11):806-818. doi: 10.1002/sctm.17-0269. PMID: 30085415 |
| 110. | Kimura H*, Ouchi T*, Shibata S*, Amemiya T, Nagoshi N, Nakagawa T, Matsumoto M, Okano H, Nakamura M, Sato K. “Stem cells purified from human induced pluripotent stem cell-derived neural crest-like cells promote peripheral nerve regeneration.” Scientific Reports. 2018 Jul 3;8(1):10071. doi: 10.1038/s41598-018-27952-7. PMID: 29968745 (*equally contributed first author) |
| 111. | Ouchi T, Morikawa S, Shibata S, Takahashi M, Yoshikawa M, Soma T, Miyashita H, Muraoka W, Kameyama K, Kawana H, Arima Y, Saya H, Okano H, Nakagawa T, Asoda S. “Recurrent Spindle Cell Carcinoma Shows Features of Mesenchymal Stem Cells.” J Dent Res. 2018 Jul;97(7):779-786. doi: 10.1177/0022034518759278. PMID: 29494307 |
| 112. | He J, Yamane M, Shibata S, Fukui M, Shimizu E, Yano T, Mukai S, Kawakami Y, Li S, Tsubota K, Ogawa Y. “Ocular Surface and Tear Film Characteristics in a Sclerodermatous Chronic Graft-Versus-Host Disease Mouse Model.”, Cornea. 2018 Apr;37(4):486-494. doi: 10.1097/ICO.0000000000001487. PMID: 29341972 |
2017年
| 113. | Fukuhara S, Masaoka T, Nishimura S, Nakamura M, Matsuzaki J, Tsugawa H, Miyoshi S, Mori H, Kawase S, Shibata S, Okano H, Kanai T, Suzuki H. “Enteric Glial Dysfunction Evoked by Apolipoprotein E Deficiency Contributes to Delayed Gastric Emptying”, Dig Dis Sci. 2017 Dec;62(12):3359-3369. doi: 10.1007/s10620-017-4820-7. Epub 2017 Nov 2. PMID: 29098550 |
| 114. | Mori T, Sukeda A, Sekine S, Shibata S, Ryo E, Okano H, Suzuki S, and Hiraoka N. “SOX10 expression as well as BRAF and GNAQ/11 mutations distinguish pigmented ciliary epithelium neoplasms from uveal melanomas”, Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5445-5451. doi: 10.1167/iovs.17-22362. PMID: 29059311 |
| 115. | Suzuki H, Ahuja CS, Salewski RP, Li L, Satkunendrarajah K, Nagoshi N, Shibata S, Fehlings MG. “Neural stem cell mediated recovery is enhanced by Chondroitinase ABC pretreatment in chronic cervical spinal cord injury.”, PLoS One. 2017 Aug 3;12(8):e0182339. doi: 10.1371/journal.pone.0182339. eCollection 2017. PMID: 28771534 |
| 116. | Kodo K, Shibata S, Miyagawa-Tomita S, Ong SG, Takahashi H, Kume T, Okano H, Matsuoka R, Yamagishi H. “Regulation of Sema3c and the Interaction between Cardiac Neural Crest and Second Heart Field during Outflow Tract Development.” Scientific Reports, 2017 Jul 28;7(1):6771. doi: 10.1038/s41598-017-06964-9. PMID: 28754980 |
| 117. | Morizawa YM, Hirayama Y, Ohno N, Shibata S, Shigetomi E, Sui Y, Nabekura J, Sato K, Okajima F, Takebayashi H, Okano H, Koizumi S. “Reactive astrocytes function as a phagocyte after brain ischemia via ABCA1-mediated pathway.” Nat Commun. 2017 Jun 22;8(1):28. doi: 10.1038/s41467-017-00037-1. PMID: 28642575 |
| 118. | Takano M, Kawabata S, Shibata S, Yasuda A, Nori S, Tsuji O, Nagoshi N, Iwanami A, Ebise H, Horiuchi K, Okano H, Nakamura M. “Enhanced Functional Recovery from Spinal Cord Injury in Aged Mice after Stem Cell Transplantation through HGF Induction.” Stem Cell Reports. 2017 Mar 14;8(3):509-518. doi: 10.1016/j.stemcr.2017.01.013. Epub 2017 Feb 16. PMID: 28216143 |
| 119. | Inagaki E, Hatou S, Higa K, Yoshida S, Shibata S, Okano H, Tsubota K, Shimmura S. “Skin-Derived Precursors as a Source of Progenitors for Corneal Endothelial Regeneration.” Stem Cells Transl Med. 2017 Mar;6(3):788-798. doi: 10.1002/sctm.16-0162. PMID: 28186681 |
| 120. | Takayama Y, Wakabayashi T, Kushige H, Saito Y, Shibuya Y, Shibata S, Akamatsu W, Okano H, Kida YS. “Brief exposure to small molecules allows induction of mouse embryonic fibroblasts into neural crest-like precursors.” FEBS Lett. 2017 Feb;591(4):590-602. doi: 10.1002/1873-3468.12572. Epub 2017 Feb 9. PMID: 28129669 |
2016年
| 121. | Shinozaki M, Iwanami A, Fujiyoshi K, Tashiro S, Kitamura K, Shibata S, Fujita H, Nakamura M, Okano H. “Combined treatment with chondroitinase ABC and treadmill rehabilitation for chronic severe spinal cord injury in adult rats.” Neurosci Res. 2016 Dec;113:37-47. doi: 10.1016/j.neures.2016.07.005. PMID: 27497528 |
| 122. | Ouchi T, Morikawa S, Shibata S, Fukuda K, Okuno H, Fujimura T, Kuroda T, Ohyama M, Akamatsu W, Nakagawa T Okano H. “LNGFR+THY-1+ Human Pluripotent Stem Cell-derived Neural Crest-Like Cells Have the Potential to Develop Into Mesenchymal Stem Cells.” Differentiation. 2016 Dec;92(5):270-280. doi: 10.1016/j.diff.2016.04.003. Epub 2016 May 10. PMID: 27178356 |
| 123. | Komaki Y, Hikishima K, Shibata S, Konomi T, Seki F, Yamada M, Miyasaka N, Fujiyoshi K, Okano HJ, Nakamura M, *Okano H. “Functional brain mapping using specific sensory-circuit stimulation and a theoretical graph network analysis in mice with neuropathic allodynia.” Scientific Reports, 2016 Nov 29;6:37802. doi: 10.1038/srep37802. PMID: 27898057 |
| 124. | Futatsugi K, Tokuyama H, Shibata S, Naitoh M, Kanda T, Minakuchi H, Yamaguchi S, Hayashi K, Minamishima YA, Yanagita M, Wakino S, *Itoh H. “Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules.” Scientific Reports, 2016 Nov 9;6:36533. doi: 10.1038/srep36533. PMID: 27827416 |
| 125. | Fujimura K, Mitsuhashi T, Shibata S, Shimozato S, *Takahashi T. “In utero exposure to valproic acid induces neocortical dysgenesis via dysregulation of neural progenitor cell proliferation/differentiation.” J Neurosci.. 2016 Oct 19;36(42):10908-10919. doi: 10.1523/JNEUROSCI.0229-16.2016. PMID: 27798144 |
| 126. | Narumi S, Amano N, Ishii T, Katsumata N, Muroya K, Adachi M, Toyoshima K, Tanaka Y, Fukuzawa R, Miyako K, Kinjo S, Ohga S, Ihara K, Inoue H, Kinjo T, Hara T, Kohno M, Yamada S, Urano H, Kitagawa Y, Tsugawa K, Higa A, Miyawaki M, Okutani T, Kizaki Z, Hamada H, Kihara M, Shiga K, Yamaguchi T, Kenmochi M, Kitajima H, Fukami M, Shimizu A, Kudoh J, Shibata S, Okano H, Miyake N, Matsumoto N, Hasegawa T. “Syndromic Adrenal Hypoplasia Caused by Activating SAMD9 Mutations” Nature Genetics 2016 Jul;48(7):792-797. doi: 10.1038/ng.3569. Epub 2016 May 16. PMID: 27182967 |
| 127. | Fox RG, Lytle NK, Jaquish DV, Park FD, Ito T, Bajaj J, Koechlein CS, Zimdahl B, Yano M, Kopp JL, Kritzik M, Sicklick JK, Sander M, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek MA, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod AR, Lowy AM, Reya T. “Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma.” Nature. 2016 Jun 6;534(7607):407-411. doi: 10.1038/nature17988. PMID: 27281208 |
| 128. | Inagaki Y, Fujioka M, Kanzaki S, Watanabe K, Oishi N, Itakura G, Yasuda A, Shibata S, Nakamura M, Okano HJ, Okano H, Ogawa K. “Sustained Effect of Hyaluronic Acid in Subcutaneous Administration to the Cochlear Spiral Ganglion.” PLoS One. 2016 Apr 21;11(4):e0153957. doi: 10.1371/journal.pone.0153957. eCollection 2016. PMID: 27099926 |
| 129. | Fujimura T*, Shibata S*, Shimojima N, Morikawa Y, Okano H, Kuroda T. “Fluorescence Visualization of the Enteric Nervous Network in a Chemically Induced Aganglionosis Model” PLoS One. 2016 Mar 4;11(3):e0150579. doi: 10.1371/journal.pone.0150579. eCollection 2016. PMID: 26943905
(*equally contributed first author) |
| 130. | Fujiyoshi K, Hikishima K, Nakahara J, Tsuji O, Hata J, Konomi T, Nagai T, Shibata S, Kaneko S, Iwanami A, Momoshima S, Takahashi S, Jinzaki M, Suzuki N, Toyama Y, Nakamura M, Okano H. “Application of q-Space Diffusion MRI for the Visualization of White Matter” J Neurosci. 2016 Mar 2;36(9):2796-808. doi: 10.1523/JNEUROSCI.1770-15.2016. PMID: 26937016 |
| 131. | Morikawa S, Ouchi T, Shibata S, Fujimura T, Kawana H, Okano H, Nakagawa T. “Applications of Mesenchymal Stem Cells and Neural Crest Cells in Craniofacial Skeletal Research.” Stem Cells International, 2016; 2016:2849879. doi: 10.1155/2016/2849879. Epub 2016 Feb 24. PMID: 27006661 |
| 132. | Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, Nakamura M, Okano H, “Grafted human iPS cell-derived oligodendrocyte precursor cells contribute to robust remyelination of demyelinated axons after spinal cord injury”. Stem Cell Reports. 2016 Jan 12;6(1):1-8. doi: 10.1016/j.stemcr.2015.11.013. PMID: 26724902 |
2015年
| 133. | Shibata S*, Murota Y, Yoshimura M, Nagai T, Okano H, Siomi MC*. “Immuno-Electron Microscopy and Electron Microscopic In Situ Hybridization for Visualizing piRNA Biogenesis Bodies in Drosophila Ovaries.” Methods in Mol Biol. 2015;1328:163-78. doi: 10.1007/978-1-4939-2851-4_12. PMID: 26324437,
(*co-corresponding author) |
| 134. | Kanzaki S, Watanabe K, Fujioka M, Shibata S, Nakamura M, Okano HJ, Okano H, Ogawa K. “Novel in vivo imaging analysis of an inner ear drug delivery system: drug availability in inner ear following different dose of systemic drug injections.” Hearing Research. 2015 Dec;330(Pt A):142-6. doi: 10.1016/j.heares.2015.09.018. PMID: 26435094 |
| 135. | Nishikawa R, Hotta R, Shimojima N, Shibata S, Nagoshi N, Nakamura M, Matsuzaki Y, Okano HJ, Kuroda T, Okano H, Morikawa Y. “Migration and differentiation of transplanted enteric neural crest-derived cells in murine model of Hirschsprung's disease.” Cytotechnology. 2015 Aug;67(4):661-70. doi: 10.1007/s10616-014-9754-8. PMID: 25230796 |
| 136. | Iwai H, Shimada H, Nishimura S, Kobayashi Y, Itakura G, Hori K, Hikishima K, Ebise H, Negishi N, Shibata S, Habu S, Toyama Y, Nakamura M, Okano H. ” Allogeneic Neural Stem/Progenitor Cells Derived From Embryonic Stem Cells Promote Functional Recovery After Transplantation Into Injured Spinal Cord of Nonhuman Primates” Stem Cells Transl Med. 2015 Jul;4(7):708-19. doi: 10.5966/sctm.2014-0215. PMID: 26019226 |
| 137. | Lin ZY, Hirano T, Shibata S, Seki NM, Kitajima R; Sedohara A, Siomi MC, Sasaki E, Siomi H, Imamura M, Okano H. “Gene expression ontogeny of spermatogenesis in the marmoset uncovers primate characteristics during testicular development” Developmental Biology. 2015 Apr 1;400(1):43-58. doi: 10.1016/j.ydbio.2015.01.014. PMID: 25624265 |
| 138. | Shibata S, Komaki Y, Seki F, Inouye MO, Nagai T, Okano H, “Connectomics: Comprehensive approaches for whole brain mapping” Microscopy. 2015 Feb;64(1):57-67. doi: 10.1093/jmicro/dfu103. pii: dfu103. PMID: 25527636 |
2014年
| 139. | Nishimura S, Sasaki T, Shimizu A, Yoshida K, Iwai H, Koya I, Kobayashi Y, Itakura G, Shibata S, Ebise H, Horiuchi K, Kudoh J, Toyama Y, Anderson AJ, Okano H, Nakamura M. “Global gene expression analysis following spinal cord injury in non-human primates.” Exp Neurol. 2014 Nov;261:171-179. doi: 10.1016/j.expneurol.2014.05.021. Epub 2014 May 27. PMID: 24873731 |
| 140. | Murota Y, Ishizu H, Nakagawa S, Iwasaki YW, Shibata S, Kamatani MK, Saito K, Okano H, Siomi H, Siomi MC. “Yb Integrates piRNA Intermediates and Processing Factors into Perinuclear Bodies to Enhance piRISC Assembly.” Cell Report. 2014 Jul 10;8(1):103-13. pii: S2211-1247(14)00437-9. doi: 10.1016/j.celrep.2014.05.043. PMID: 24953657 |
| 141. | Zhang L, Kaneko S, Kikuchi K, Sano A, Maeda M, Kishino A, Shibata S, Mukaino M, Toyama Y, Liu M, Kimura T, Okano H, Nakamura M. “Rewiring of regenerated axons by combining treadmill training with semaphorin3A inhibition.” Molecular Brain. 2014 Mar 10;7(1):14. doi: 10.1186/1756-6606-7-14. PMID: 24618249 |
| 142. | Takano M, Kawabata S, Komaki Y, Shibata S, Hikishima K, Toyama Y, Okano H, Nakamura M. “Inflammatory cascades mediate synapse elimination in spinal cord compression.” J of Neuroinflammation. 2014 Mar 4;11(1):40. doi: 10.1186/1742-2094-11-40. PMID: 24589419 |
| 143. | Kuroiwa-Numasawa Y, Okada Y, Shibata S, Kishi N, Akamatsu W, Shoji M, Nakanishi A, Oyama M, Osaka H, Inoue K, Takahashi K, Yamanaka S, Kosaki K, Takahashi T, Okano H. “Involvement of ER stress in dysmyelination of Pelizaeus-Merzbacher disease with PLP1 missense mutations shown by iPSC-derived oligodendrocytes” Stem Cell Reports, 2014 Apr 24;2(5):648-61. doi: 10.1016/j.stemcr.2014.03.007. PMID: 24936452 |
2013年
| 144. | Ohtomo R, Mori T, Shibata S, Tsuta K, Maeshima M, Akazawa C, Honda K, Yamada T, Yoshimoto S, Asai M, Okano H, Kanai Y, Tsuda H. “Sox10 is a novel marker of acinus and intercalated duct differentiation in salivary gland tumors: A clue to the histogenesis and diagnosis” Modern Pathology 2013, Aug;26(8):1041-50. doi: 10.1038/modpathol.2013.54. PMID: 23558573, |
| 145. | Nishimoto Y, Nakagawa S, Hirose T, Okano HJ, Takao M, Shibata S, Suyama S, Kuwako K, Imai T, Murayama S, Suzuki N, Okano H. “The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.” Molecular Brain. 2013 Jul 8;6:31. doi: 10.1186/1756-6606-6-31. PMID: 23835137, |
| 146. | Sato H, Shibata M, Shimizu T, Shibata S, Toriumi H, Ebine T, Kuroi T, Iwashita T, Funakubo M, Kayama Y, Akazawa C, Wajima K, Nakagawa T, Okano H, Suzuki N. “Differential cellular localization of antioxidant enzymes in the trigeminal ganglion.” Neuroscience. 2013 Jun 15;248C:345-358. doi: 10.1016/j.neuroscience.2013.06.010. PMID: 23774632, |
| 147. | Fukuda T, Takeda S, Xu R, Ochi H, Sunamura S, Sato T, Shibata S, Yoshida Y, Gu Z, Kimura A, Ma C, Xu C, Bando W, Fujita K, Shinomiya K, Hirai T, Asou Y, Enomoto M, Okano H, Okawa A, Itoh H. “Sema3A regulates bone-mass accrual through sensory innervations.” Nature. 2013 May 23;497(7450):490-3. doi: 10.1038/nature12115. PMID: 23644455, |
| 148. | Takahashi T, Suzuki H, Imai T, Shibata S, Tabuchi Y, Tsuchimoto K, Okano H, Hibi T. “Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain-containing m-Numb protein expression in regenerating gastric mucosa.” PLoS One. 2013;8(1):e53540. doi: 10.1371/journal.pone.0053540. PMID: 23308249 |
2012年
| 149. | Takagi T, Kimura Y, Shibata S, Saito H, Ishii K, Okano HJ, Toyama Y, Okano H, Tabata Y, Nakamura M. “Sustained bFGF-Release Tubes for Peripheral Nerve Regeneration: Comparison with Autograft.” Plast Reconstr Surg. 2012 Oct;130(4):866-76. doi: 10.1097/PRS.0b013e318262f36e. PMID: 23018697 |
| 150. | Takano M, Hikishima K, Fujiyoshi K, Shibata S, Yasuda A, Konomi T, Hayashi A, Baba H, Honke K, Toyama Y, Okano H, Nakamura M. “MRI characterization of paranodal junction failure and related spinal cord changes in mice” PLoS One. 2012;7(12):e52904. doi: 10.1371/journal.pone.0052904. PMID: 23300814, |
| 151. | Kanzaki S, Fujioka M, Yasuda A, Shibata S, Nakamura M, Okano HJ, Ogawa K, Okano H. “Novel in vivo imaging analysis of an inner ear drug delivery system in mice: Comparison of inner ear drug concentrations over time after transtympanic and systemic injections” PLoS One. 2012;7(12):e48480. doi: 10.1371/journal.pone.0048480. PMID: 23251331 |
| 152. | Omoto M, Yoshida S, Miyashita H, Kawakita T, Yoshida K, Kishino A, Kimura T, Shibata S, Tsubota K, Okano H, Shimmura S. “The Semaphorin 3A Inhibitor SM-345431 Accelerates Peripheral Nerve Regeneration and Sensitivity in a Murine Corneal Transplantation Model.” PLoS One. 2012;7(11):e47716. doi: 10.1371/journal.pone.0047716. PMID: 23152758 |
| 153. | Shibata S, Umei M, Kawahara H, Yano M, Makino S, Okano H. “Characterization of the RNA-binding protein Musashi1 in zebrafish.” Brain Research. 2012 Jun 26;1462:162-73. Epub 2012 Feb 3, doi: 10.1016/j.brainres.2012.01.068, PMID: 22429745, |
2011年
| 154. | Yasuda A, Tsuji O, Shibata S, Nori S, Takano M, Kobayashi Y, Takahashi Y, Fujiyoshi K, Hara CM, Miyawaki A, Okano HJ, Toyama Y, Nakamura M, Okano H. “Significance of remyelination by neural stem/progenitor cells transplanted into the injured spinal cord.” Stem Cells. 2011 Dec;29(12):1983-94. doi: 10.1002/stem.767. PMID: 22028197 |
| 155. | Renault-Mihara F, Katoh H, Ikegami T, Iwanami A, Mukaino M, Yasuda A, Nori S, Mabuchi Y, Tada H, Shibata S, Saito K, Matsushita M, Kaibuchi K, Okada S, Toyama Y, Nakamura M, Okano H. “Beneficial compaction of spinal cord lesion by migrating astrocytes through glycogen synthase kinase-3 inhibition.” EMBO Molecular Medicine. 2011 Nov;3(11):682-96. doi: 10.1002/emmm.201100179. PMID: 21898827 |
| 156. | Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M. “Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice.” Journal of Clinical Investigation. 2011 Oct;121(10):3981-90. doi: 10.1172/JCI57301. PMID: 21911936 |
| 157. | Katoh H, Shibata S, Fukuda K, Sato M, Satoh E, Nagoshi N, Minematsu T, Matsuzaki Y, Akazawa C, Toyama Y, Nakamura M, Okano H. “The dual origin of the peripheral olfactory system: placode and neural crest.” Molecular Brain. 2011 Sep 23;4:34. doi: 10.1186/1756-6606-4-34, PMID: 21943152, PMCID: PMC3215936 |
| 158. | Takagi T, Ishii K, Shibata S, Yasuda A, Sato M, Nagoshi N, Saito H, Okano HJ, Toyama Y, Okano H, Nakamura M. “Schwann-spheres derived from injured peripheral nerves in adult mice--their in vitro characterization and therapeutic potential.” PLoS One. 2011;6(6):e21497. doi: 10.1371/journal.pone.0021497, PMID: 21720551, PMCID: PMC3123355 |
| 159. | Hosoya M, Fujioka M, Matsuda S, Ohba H, Shibata S, Nakagawa F, Watabe T, Wakabayashi KI, Saga Y, Ogawa K, Okano HJ, Okano H. “Expression and Function of Sox21 During Mouse Cochlea Development.” Neurochem Res. 2011 Jul;36(7):1261-9. doi: 10.1007/s11064-011-0416-3. PMID: 21287267 |
| 160. | Nagoshi N, Shibata S, Hamanoue M, Mabuchi Y, Matsuzaki Y, Toyama Y, Nakamura M, Okano H. “Schwann cell plasticity after spinal cord injury shown by neural crest lineage tracing.” Glia 2011 May;59(5):771-84. doi: 10.1002/glia.21150. Epub 2011 Feb 23, PMID: 21351159 |
2010年
| 161. | Shibata S, Yasuda A, Renault-Mihara F, Suyama S, Katoh H, Inoue T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, Okano H. “Sox10-Venus mice: a new tool for real time labelling of neural crest lineage and oligodendrocytes.” Molecular Brain. 2010 Oct 31; 3(1):31. doi: 10.1186/1756-6606-3-31. PMID: 21034515 |
| 162. | Aihara Y, Hayashi Y, Hirata M, Ariki N, Shibata S, Nagoshi N, Nakanishi M, Ohnuma K, Warashina M, Michiue T, Uchiyama H, Okano H, Asashima M, Furue MK. “Induction of neural crest cells from mouse embryonic stem cells in a serum-free monolayer culture” Int. J. Dev. Biol. 2010;54(8-9):1287-94. doi: 10.1387/ijdb.103173ya. PMID: 20711997, |
| 163. | Suzuki S, Namiki J, Shibata S, Mastuzaki Y, Okano H. “The Neural Stem/progenitor Cell Marker Nestin is Expressed in Proliferative Endothelial Cells, but Not in Mature Vasculature” J Histochem Cytochem. 2010 Aug;58(8):721-30. doi: 10.1369/jhc.2010.955609. PMID: 20421592 |
| 164. | Wakabayashi K, Fujioka M, Kanzaki S, Okano HJ, Shibata S, Yamashita D, Masuda M, Mihara M, Ohsugi Y, Ogawa K, Okano H. “Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea.” Neurosci Res. 2010 Apr;66(4):345-52. doi: 10.1016/j.neures.2009.12.008. PMID: 20026135 |
| 165. | Tada H, Okano HJ, Takagi H, Shibata S, Yao I, Matsumoto M, Saiga T, Nakayama KI, Kashima H, Takahashi T, Setou M, Okano H. “Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.” J Biol Chem. 2010 Feb 5;285(6):3840-9. doi: 10.1074/jbc.M109.046284. PMID: 19996097 |
2009年
| 166. | Kumagai G, Okada Y, Yamane J, Nagoshi N, Kitamura K, Mukaino M, Tsuji O, Fujiyoshi K, Katoh H, Okada S, Shibata S, Matsuzaki Y, Toh S, Toyama Y, Nakamura M, Okano H. “Roles of ES cell-derived gliogenic neural stem/progenitor cells in functional recovery after spinal cord injury.” PLoS One. 2009 Nov 6;4(11):e7706. doi: 10.1371/journal.pone.0007706. PMID: 19893739 |
| 167. | Hamanoue M, Matsuzaki Y, Sato KI, Okano HJ, Shibata S, Sato I, Suzuki S, Ogawara M, Takamatsu K, Okano H. “Cell surface N-glycans mediated isolation of mouse neural stem cells.” Journal of Neurochemistry. 2009 Sep;110(5):1575-84. doi: 10.1111/j.1471-4159.2009.06256.x. PMID: 19573022 |
| 168. | Nagoshi N, Shibata S, Nakamura M, Matsuzaki Y, Toyama Y, Okano H. “Neural crest-derived stem cells display a wide variety of characteristics” J Cell Biochem. 2009 Aug 15;107(6):1046-52. doi: 10.1002/jcb.22213. PMID: 19479900 |
2008年
| 169. | Susaki K, Kaneko J, Yamano Y, Nakamura K, Inami W, Yoshikawa T, Ozawa Y, Shibata S, Matsuzaki O, Okano H, Chiba C, “Musashi-1, an RNA-binding protein, is indispensable for survival of photoreceptors” Experimental Eye Research 2009 Mar;88(3):347-55. doi: 10.1016/j.exer.2008.06.019. PMID: 18662689 |
| 170. | Takagi T, Nakamura M, Yamada M, Hikishima K, Momoshima S, Fujiyoshi K, Shibata S, Okano HJ, Toyama Y, Okano H. “Visualization of peripheral nerve degeneration and regeneration: Monitoring with diffusion tensor tractography.” Neuroimage. 2009 Feb 1;44(3):884-92. doi: 10.1016/j.neuroimage.2008.09.022. PMID: 18948210 |
| 171. | Renault-Mihara F, Okada S, Shibata S, Nakamura M, Toyama Y, Okano H. “Spinal cord injury: emerging beneficial role of reactive astrocytes' migration.” Int J Biochem Cell Biol. 2008;40(9):1649-53. doi: 10.1016/j.biocel.2008.03.009. PMID: 18434236 |
| 172. | Nagoshi N, Shibata S, Kubota Y, Nakamura M, Nagai Y, Satoh E, Morikawa S, Okada Y, Mabuchi Y, Katoh H, Okada S, Fukuda K, Suda T, Matsuzaki Y, Toyama Y, Okano H. “Ontogeny and multipotency of neural crest-derived stem cells in mouse bone marrow, dorsal root ganglia, and whisker pad.” Cell Stem Cell. 2008 Apr 10;2(4):392-403. doi: 10.1016/j.stem.2008.03.005. PMID: 18397758 |
2007年
| 173. | Kitamuta K., Iwanami A., Nakamura M., Yamane J, Kota W, Suzuki Y, Miyakawa D, Shibata S, Funakoshi H, Miyatakae S, Coffin R, Nakamura T, Toyama Y, Okano H: “Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury.” J. Neurosci Res. 2007 Aug 15;85(11):2332-42. DOI: 10.1002/jnr.21372, PMID: 17549731 |
2006年
| 174. | Kaneko S, Iwanami A, Nakamura M, Kishino A, Kikuchi K, Shibata S, Okano HJ, Ikegami T, Moriya A, Konishi O, Nakayama C, Kumagai K, Kimura T, Sato Y, Goshima Y, Taniguchi M, Ito M, He Z, Toyama Y, Okano H. “A selective Sema3A inhibitor enhances regenerative responses and functional recovery of the injured spinal cord.” Nat Med. 2006 Dec;12(12):1380-9. DOI: 10.1038/nm1505, PMID: 17099709 |
| 175. | Sugiyama-Nakagiri Y, Akiyama M, Shibata S, Okano H, Shimizu H. “Expression of RNA-binding protein Musashi in hair follicle development and hair cycle progression.” Am J Pathology 2006 Jan; 168(1): 80-92. DOI: 10.2353/ajpath.2006.050469, PMID: 16400011 |
2005年
| 176. | Okano H., Kawahara H., Toriya M., Nakao K., Shibata S. and Imai T. “Function of RNA binding protein Musashi-1 in stem cells.” Exp. Cell Res. 2005 Jun 10;306(2):349-56. DOI: 10.1016/j.yexcr.2005.02.021 PMID: 15925591 |
| 177. | Akamatsu W, Fujihara H, Mitsuhashi T, Yano M, Shibata S, Hayakawa Y, Okano HJ, Sakakibara SI, Takano H, Takano T, Takahashi T, Noda T, Okano H. “The RNA-binding protein HuD regulates neuronal cell identity and maturation.” Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4625-30. doi: 10.1073/pnas.0407523102. Epub 2005 Mar 11. PMID: 15764704 |
2002年
| 178. | Sakakibara S, Nakamura Y, Yoshida T, Shibata S, Koike M, Takano H, Ueda S, Uchiyama Y, Noda T, Okano H. “RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation.” Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15194-9. doi: 10.1073/pnas.232087499. Epub 2002 Oct 29. PMID: 12407178PMID: 12407178 |
2000年
| 179. | Fujino T, Hasegawa M, Shibata S, Kishimoto T, Imai SI, Takano T. “PCCX1, a novel DNA-binding protein with PHD finger and CXXC domain, is regulated by proteolysis.” Biochem Biophys Res Commun. 2000 May 10;271(2):305-10. doi: 10.1006/bbrc.2000.2614. PMID: 10799292 |
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