新潟大学大学院医歯学総合研究科
機能制御学分野

Hva22, a REEP family protein in fission yeast, promotes reticulophagy in collaboration with a receptor protein.
Fukuda T*, Saigusa T, Furukawa K, Inoue K, Yamashita SI, Kanki T*.
Autophagy. 2023; DOI: 10.1080/15548627.2023.2214029.

The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy.
Fukuda T#, Furukawa K#, Maruyama T#, Yamashita SI, Noshiro D, Song C, Ogasawara Y, Okuyama K, Alam JM, Hayatsu M, Saigusa T, Inoue K, Ikeda K, Takai A, Chen L, Lahiri V, Okada Y, Shibata S, Murata K, Klionsky DJ, Noda NN*, Kanki T*.
Mol Cell. 2023; DOI:https://doi.org/10.1016/j.molcel.2023.04.022.
#Equal contribution
*Corresponding authors

TIM23 facilitates PINK1 activation by safeguarding against OMA1-mediated degradation in damaged mitochondria.
Akabane S, Watanabe K, Kosako H, Yamashita SI, Nishino K, Kato M, Sekine S, Kanki T, Matsuda N, Endo T, Oka T*.
Cell Rep. 2023; DOI:https://doi.org/10.1016/j.celrep.2023.112454.