研究業績(原著論文)
Mutation and functional analysis of ABCC2/multidrug resistance protein 2 in a Japanese patient with Dubin-Johnson syndrome.
Uchiumi T, Tanamachi H, Kuchiwaki K, Kajita M, Matsumoto S, Yagi M, Kanki T, Kang D.
Hepatol Res. 2013; 43(5): 569-575.
2012
Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients.
Fang J, Uchiumi T, Yagi M, Matsumoto S, Amamoto R, Saito T, Takazaki S, Kanki T, Yamaza H, Nonaka K, Kang D.
Biosci Rep. 2012; 32(6): 631-639.
p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability.
Yagi M, Uchiumi T, Takazaki S, Okuno B, Nomura M, Yoshida S, Kanki T, Kang D.
Nucleic Acids Res. 2012; 40(19): 9717-9737.
Localization of mRNAs encoding human mitochondrial oxidative phosphorylation proteins.
Matsumoto S, Uchiumi T, Saito T, Yagi M, Takazaki S, Kanki T, Kang D.
Mitochondrion. 2012; 12(3): 391-398.
Ribonucleoprotein Y-box-binding protein-1 regulates mitochondrial oxidative phosphorylation (OXPHOS) protein expression after serum stimulation through binding to OXPHOS mRNA.
Matsumoto S, Uchiumi T, Tanamachi H, Saito T, Yagi M, Takazaki S, Kanki T, Kang D.
Biochem J. 2012; 443(2): 573-584.
Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast.
Kurihara Y, Kanki T, Aoki Y, Hirota Y, Saigusa T, Uchiumi T, Kang D.
J Biol Chem. 2012; 287(5): 3265-3272.
2011
Phosphorylation of Serine 114 on Atg32 mediates mitophagy.
Aoki Y, Kanki T, Hirota Y, Kurihara Y, Saigusa T, Uchiumi T, Kang D.
Mol Biol Cell. 2011; 22(17): 3206-3217.
2009
A genomic screen for yeast mutants defective in selective mitochondria autophagy.
Kanki T, Wang K, Baba M, Bartholomew CR, Lynch-Day MA, Du Z, Geng J, Mao K, Yang Z, Yen WL, Klionsky DJ.
Mol Biol Cell. 2009; 20(22): 4730-4738.
Atg32 is a mitochondrial protein that confers selectivity during mitophagy.
Kanki T, Wang K, Cao Y, Baba M, Klionsky DJ.
Dev Cell. 2009; 17(1): 98-109.
2008
Mitophagy in yeast occurs through a selective mechanism.
Kanki T, Klionsky DJ.
J Biol Chem. 2008; 283(47): 32386-32393.